period. This subsequently leads to several complex diseases in humans in the form of
neurodegenerative disorders, weakened immune system, kidney malfunction, skeletal deformities, liver abnormalities, heart disorders, reproductive impairments and
sexual disorders. A health report from WHO suggests that more than 90% of the
bioaccumulated dioxins/furans come from food ingestion. A schematic representation of the sources of dioxins and furans and possible disorders of such contamination is given in Fig. 14.2.
14.7.1 Cancer
Dioxins and furans are considered to be one among the deadliest carcinogens to
humans according to a report from the WHO report. They are classified as level
1 carcinogen ever known to the history of mankind. 2,3,7,8-TCDD is the most
studied congener of all compounds known to humans. The USEPA classifies this
compound as the “strongest known carcinogen” and also as the “complete
Fig. 14.2 Schematic representation of sources of dioxins/furans and its impact on humans
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J. G. A. Jeno et al.
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