Wang X, He Q, Yang Y, Wang J, Haning K, Hu Y et al (2018) Advances and prospects in metabolic
engineering of Zymomonas mobilis. Metab Eng 50:57–73
Widiastuti H, Kim JY, Selvarasu S, Karimi IA, Kim H, Seo JS, Lee DY (2011) Genome-scale
modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Biotechnol
Bioeng 108(3):655–665
Winkler JD, Kao KC (2014) Recent advances in the evolutionary engineering of industrial
biocatalysts. Genomics 104(6 Pt A):406–411
Wirawan F, Cheng CL, Lo YC, Chen CY, Chang JS, Leu SY, Lee DJ (2020) Continuous cellulosic
bioethanol co-fermentation by immobilized Zymomonas mobilis and suspended Pichia stipitis
in a two-stage process. Appl Energy 266:114871
Yang S, Pelletier DA, Lu TYS, Brown SD (2010a) The Zymomonas mobilis regulator hfq
contributes to tolerance against multiple lignocellulosic pretreatment inhibitors. BMC Microbiol
10(1):135
Yang S, Land ML, Klingeman DM, Pelletier DA, Lu TY, Martin SL et al (2010b) Paradigm for
industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis
and Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107:10395–10400
Yang S, Fei Q, Zhang Y, Contreras LM, Utturkar SM, Brown SD et al (2016a) Zymomonas mobilis
as a model system for production of biofuels and biochemicals. Microb Biotechnol 9
(6):699–717
Yang S, Mohagheghi A, Franden MA, Chou Y-C, Chen X, Dowe N et al (2016b) Metabolic
engineering of Zymomonas mobilis for 2, 3-butanediol production from lignocellulosic biomass
sugars. Biotechnol Biofuels 9(1):189
Yang JW, Kim J, Yoo G, Lee H, Lim J, Kim CW et al (2013) Methods of downstream processing
for the production of biodiesel from microalgae. Biotechnol Adv 31(6):862–876
Yang Y, Shen W, Huang J, Li R, Xiao Y, Wei H et al (2019) Prediction and characterization of
promoters and ribosomal binding sites of Zymomonas mobilis in system biology era. Biotechnol
Biofuels 12(1):52
Yi X, Gu H, Gao Q, Liu ZL, Bao J (2015) Transcriptome analysis of Zymomonas mobilis ZM4
reveals mechanisms of tolerance and detoxification of phenolic aldehyde inhibitors from
lignocellulose pretreatment. Biotechnol Biofuels 8(1):153
Zhang X, Huang G, Chen F, Wei D, Chen G (2010) Biodiesel production by microalgal biotechnology. Appl Energy 87(1):38–46
Zhang J, Lynd LR (2010) Ethanol production from paper sludge by simultaneous saccharification
and co-fermentation using recombinant xylose-fermenting microorganisms. Biotechnol Bioeng
107:235–244
Zhang M, Eddy C, Deanda K, Finkelstein M, Picataggio S (1995) Metabolic engineering of a
pentose metabolism pathway in ethanologenic Zymomonas mobilis. Science 267
(5195):240–243
Zhang M, Chou Y-C, Picataggio SK, Finkelstein M (1998) Single Zymomonas mobilis strain for
xylose and arabinose fermentation. Google Patents
Zhang X, Wang T, Zhou W, Jia X, Wang H (2013) Use of a Tn5-based transposon system to create
a cost-effective Zymomonas mobilis for ethanol production from lignocelluloses. Microb Cell
Factories 12(1):41
Zhang T, Hu Y, Jiang W, Fang L, Guan X, Chen J et al (2015) Sequencing of allotetraploid cotton
(Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement. Nat Biotechnol
33(5):531–537
Zhang K, Lu X, Li Y, Jiang X, Liu L, Wang H (2019) New technologies provide more metabolic
engineering strategies for bioethanol production in Zymomonas mobilis. Appl Microbiol
Biotechnol 103(5):2087–2099
Zheng Y, Pan Z, Zhang R (2009) Overview of biomass pretreatment for cellulosic ethanol
production. Int J Agric Biol Eng 2(3):51–68
6 Engineering of Zymomonas mobilis for Enhanced Biofuel Production
181
engineering of Zymomonas mobilis. Metab Eng 50:57–73
Widiastuti H, Kim JY, Selvarasu S, Karimi IA, Kim H, Seo JS, Lee DY (2011) Genome-scale
modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Biotechnol
Bioeng 108(3):655–665
Winkler JD, Kao KC (2014) Recent advances in the evolutionary engineering of industrial
biocatalysts. Genomics 104(6 Pt A):406–411
Wirawan F, Cheng CL, Lo YC, Chen CY, Chang JS, Leu SY, Lee DJ (2020) Continuous cellulosic
bioethanol co-fermentation by immobilized Zymomonas mobilis and suspended Pichia stipitis
in a two-stage process. Appl Energy 266:114871
Yang S, Pelletier DA, Lu TYS, Brown SD (2010a) The Zymomonas mobilis regulator hfq
contributes to tolerance against multiple lignocellulosic pretreatment inhibitors. BMC Microbiol
10(1):135
Yang S, Land ML, Klingeman DM, Pelletier DA, Lu TY, Martin SL et al (2010b) Paradigm for
industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis
and Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107:10395–10400
Yang S, Fei Q, Zhang Y, Contreras LM, Utturkar SM, Brown SD et al (2016a) Zymomonas mobilis
as a model system for production of biofuels and biochemicals. Microb Biotechnol 9
(6):699–717
Yang S, Mohagheghi A, Franden MA, Chou Y-C, Chen X, Dowe N et al (2016b) Metabolic
engineering of Zymomonas mobilis for 2, 3-butanediol production from lignocellulosic biomass
sugars. Biotechnol Biofuels 9(1):189
Yang JW, Kim J, Yoo G, Lee H, Lim J, Kim CW et al (2013) Methods of downstream processing
for the production of biodiesel from microalgae. Biotechnol Adv 31(6):862–876
Yang Y, Shen W, Huang J, Li R, Xiao Y, Wei H et al (2019) Prediction and characterization of
promoters and ribosomal binding sites of Zymomonas mobilis in system biology era. Biotechnol
Biofuels 12(1):52
Yi X, Gu H, Gao Q, Liu ZL, Bao J (2015) Transcriptome analysis of Zymomonas mobilis ZM4
reveals mechanisms of tolerance and detoxification of phenolic aldehyde inhibitors from
lignocellulose pretreatment. Biotechnol Biofuels 8(1):153
Zhang X, Huang G, Chen F, Wei D, Chen G (2010) Biodiesel production by microalgal biotechnology. Appl Energy 87(1):38–46
Zhang J, Lynd LR (2010) Ethanol production from paper sludge by simultaneous saccharification
and co-fermentation using recombinant xylose-fermenting microorganisms. Biotechnol Bioeng
107:235–244
Zhang M, Eddy C, Deanda K, Finkelstein M, Picataggio S (1995) Metabolic engineering of a
pentose metabolism pathway in ethanologenic Zymomonas mobilis. Science 267
(5195):240–243
Zhang M, Chou Y-C, Picataggio SK, Finkelstein M (1998) Single Zymomonas mobilis strain for
xylose and arabinose fermentation. Google Patents
Zhang X, Wang T, Zhou W, Jia X, Wang H (2013) Use of a Tn5-based transposon system to create
a cost-effective Zymomonas mobilis for ethanol production from lignocelluloses. Microb Cell
Factories 12(1):41
Zhang T, Hu Y, Jiang W, Fang L, Guan X, Chen J et al (2015) Sequencing of allotetraploid cotton
(Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement. Nat Biotechnol
33(5):531–537
Zhang K, Lu X, Li Y, Jiang X, Liu L, Wang H (2019) New technologies provide more metabolic
engineering strategies for bioethanol production in Zymomonas mobilis. Appl Microbiol
Biotechnol 103(5):2087–2099
Zheng Y, Pan Z, Zhang R (2009) Overview of biomass pretreatment for cellulosic ethanol
production. Int J Agric Biol Eng 2(3):51–68
6 Engineering of Zymomonas mobilis for Enhanced Biofuel Production
181