9. Xu Z, Tan H, Wang F, Hou X, Xiong A (2014)
CarrotDB: a genomic and transcriptomic database for carrot. Database 2014
10. Iorizzo M, Ellison S, Senalik D, Zeng P,
Satapoomin P, Huang J, Bowman M,
Iovene M, Sanseverino W, Cavagnaro P,
Yildiz M, Macko-Podgno ´ rni A, Moranska E,
Grzebelus E, Grzebelus D, Ashrafi H,
Zheng Z, Cheng S, Spoonder D, Van
Deynze A, Simon P (2016) A high-quality carrot genome assembly provides new insights
into carotenoid accumulation and asterid
genome evolution. Nat Genet 48:657–666
11. Ellison S, Luby C, Corak K, Coe K, Senalik D,
Iorizzo M, Goldman I, Simon P, Dawson J
(2018) Carotenoid presence is associated with
the or gene in domesticated carrot. Genetics
210:1497–1508
12. Stange C, Fuentes P, Handford M, Pizarro L
(2008) Daucus carota as a novel model to evaluate the effect of light on carotenogenic gene
expression. Biol Res 41:289–301
13. Fuentes P, Pizarro L, Moreno J, Handford M,
Rodriguez-Concepcion M, Stange C (2012)
Light-dependent changes in plastid differentiation influence carotenoid gene expression and
accumulation in carrot roots. Pant Mol Biol
79:47–59
14. Moreno J, Pizarro L, Fuentes P, Handford M,
Cifuentes V, Stange C (2013) Levels of lycopene β-cyclase 1 modulate carotenoid gene
expression and accumulation in Daucus carota.
PLoS One 8:e58144
15. Simpson
K,
Quiroz
L,
RodriguezConcepcio ´ n M, Stange C (2016b) Differential
contribution of the first two enzymes of the
MEP pathway to the supply of metabolic precursors for carotenoid and chlorophyll biosynthesis in carrot (Daucus carota). Front Plant Sci
7:1344
16. Simpson K, Fuentes P, Quiroz-Iturra L, FloresOrtiz C, Contreras R, Handford M, Stange C
(2018) Unraveling the induction of phytoene
synthase 2 expression by salt stress and abscisic
acid in Daucus carota. J Exp Bot
69:4113–4126
17. Jayaraj J, Devlin R, Punja Z (2008) Metabolic
engineering of novel ketocarotenoid production in carrot plants. Transgenic Res
17:489–501
18. Luchakivskaya
Y,
Kishchenko
O,
Gerasymenko I, Olevinskaya Z, Simonenko Y,
Spivak M, Kuchuk M (2011) High-level
expression of human interferon alpha-2b in
transgenic carrot (Daucus carota L.) plants.
Plant Cell Rep 30:407–415
19. Chen W, Punja Z (2002) Transgenic herbicideand disease-tolerant carrot (Daucus carota L.)
plants obtained through agrobacteriummediated transformation. Plant Cell Rep
20:929–935
20. Wally O, Punja Z (2010) Enhanced disease
resistance in transgenic carrot (Daucus carota
L.) plants over-expressing a rice cationic peroxidase. Planta 232:1229–1239
21. Klimek-Chodacka
M,
Oleszkiewicz
T,
Lowder L, Qi Y, Baranski R (2018) Efficient
CRISPR/Cas9-based genome editing in carrot
cells. Plant Cell Rep 37(4):575–586
22. Scott R, Draper J (1987) Transformation of
carrot tissues derived from proembryogenic
suspension cells: a useful model system for
gene expression studies in plants. Plant Mol
Biol 8:265–274
23. Pawlicki N, Sangwan R, Sangwan-Norreel B
(1992) Factors influencing the agrobacterium
tumefaciens-mediated transformation of carrot
(Daucus carota L.). Plant Cell Tissue Organ
Cult 31:129–139
24. Hardegger M, Sturm A (1998) Transformation
and regeneration of carrot (Daucus carota L.).
Mol Breeding 4:119–127
25. Baranski R (2008) Genetic transformation of
carrot (Daucus carota) and other Apiaceae species. Trans Plant J 2:18–38
320
Christian Gonzalez-Calquin and Claudia Stange
CarrotDB: a genomic and transcriptomic database for carrot. Database 2014
10. Iorizzo M, Ellison S, Senalik D, Zeng P,
Satapoomin P, Huang J, Bowman M,
Iovene M, Sanseverino W, Cavagnaro P,
Yildiz M, Macko-Podgno ´ rni A, Moranska E,
Grzebelus E, Grzebelus D, Ashrafi H,
Zheng Z, Cheng S, Spoonder D, Van
Deynze A, Simon P (2016) A high-quality carrot genome assembly provides new insights
into carotenoid accumulation and asterid
genome evolution. Nat Genet 48:657–666
11. Ellison S, Luby C, Corak K, Coe K, Senalik D,
Iorizzo M, Goldman I, Simon P, Dawson J
(2018) Carotenoid presence is associated with
the or gene in domesticated carrot. Genetics
210:1497–1508
12. Stange C, Fuentes P, Handford M, Pizarro L
(2008) Daucus carota as a novel model to evaluate the effect of light on carotenogenic gene
expression. Biol Res 41:289–301
13. Fuentes P, Pizarro L, Moreno J, Handford M,
Rodriguez-Concepcion M, Stange C (2012)
Light-dependent changes in plastid differentiation influence carotenoid gene expression and
accumulation in carrot roots. Pant Mol Biol
79:47–59
14. Moreno J, Pizarro L, Fuentes P, Handford M,
Cifuentes V, Stange C (2013) Levels of lycopene β-cyclase 1 modulate carotenoid gene
expression and accumulation in Daucus carota.
PLoS One 8:e58144
15. Simpson
K,
Quiroz
L,
RodriguezConcepcio ´ n M, Stange C (2016b) Differential
contribution of the first two enzymes of the
MEP pathway to the supply of metabolic precursors for carotenoid and chlorophyll biosynthesis in carrot (Daucus carota). Front Plant Sci
7:1344
16. Simpson K, Fuentes P, Quiroz-Iturra L, FloresOrtiz C, Contreras R, Handford M, Stange C
(2018) Unraveling the induction of phytoene
synthase 2 expression by salt stress and abscisic
acid in Daucus carota. J Exp Bot
69:4113–4126
17. Jayaraj J, Devlin R, Punja Z (2008) Metabolic
engineering of novel ketocarotenoid production in carrot plants. Transgenic Res
17:489–501
18. Luchakivskaya
Y,
Kishchenko
O,
Gerasymenko I, Olevinskaya Z, Simonenko Y,
Spivak M, Kuchuk M (2011) High-level
expression of human interferon alpha-2b in
transgenic carrot (Daucus carota L.) plants.
Plant Cell Rep 30:407–415
19. Chen W, Punja Z (2002) Transgenic herbicideand disease-tolerant carrot (Daucus carota L.)
plants obtained through agrobacteriummediated transformation. Plant Cell Rep
20:929–935
20. Wally O, Punja Z (2010) Enhanced disease
resistance in transgenic carrot (Daucus carota
L.) plants over-expressing a rice cationic peroxidase. Planta 232:1229–1239
21. Klimek-Chodacka
M,
Oleszkiewicz
T,
Lowder L, Qi Y, Baranski R (2018) Efficient
CRISPR/Cas9-based genome editing in carrot
cells. Plant Cell Rep 37(4):575–586
22. Scott R, Draper J (1987) Transformation of
carrot tissues derived from proembryogenic
suspension cells: a useful model system for
gene expression studies in plants. Plant Mol
Biol 8:265–274
23. Pawlicki N, Sangwan R, Sangwan-Norreel B
(1992) Factors influencing the agrobacterium
tumefaciens-mediated transformation of carrot
(Daucus carota L.). Plant Cell Tissue Organ
Cult 31:129–139
24. Hardegger M, Sturm A (1998) Transformation
and regeneration of carrot (Daucus carota L.).
Mol Breeding 4:119–127
25. Baranski R (2008) Genetic transformation of
carrot (Daucus carota) and other Apiaceae species. Trans Plant J 2:18–38
320
Christian Gonzalez-Calquin and Claudia Stange