1 3
Topics in Current Chemistry (2020) 378:40
234. Zheng XC, Ren W, Zhang S, Zhong T, Duan XC, Yin YF, Xu MQ, Hao YL, Li ZT, Li H, Liu
M, Li ZY, Zhang X (2018) The theranostic efficiency of tumor-specific, pH-responsive, peptidemodified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles. Int J
Nanomed 13:1495–1504. https ://doi.org/10.2147/IJN.S1570 82
235. Caro C, García-Martín ML, Pernia Leal M (2017) Manganese-based nanogels as pH switches
for magnetic resonance imaging. Biomacromol 18(5):1617–1623. https ://doi.org/10.1021/acs.
bioma c.7b002 24
236. Riedinger A, Pernia Leal M, Deka SR, George C, Franchini IR, Falqui A, Cingolani R, Pellegrino T (2011) "nanohybrids" based on pH-responsive hydrogels and inorganic nanoparticles
for drug delivery and sensor applications. Nano Lett 11(8):3136–3141
237. Jalili NA, Jaiswal MK, Peak CW, Cross LM, Gaharwar AK (2017) Injectable nanoengineered
stimuli-responsive hydrogels for on-demand and localized therapeutic delivery. Nanoscale
9(40):15379–15389. https ://doi.org/10.1039/c7nr0 2327h
238. Peng N, Ding X, Wang Z, Cheng Y, Gong Z, Xu X, Gao X, Cai Q, Huang S, Liu Y (2019)
Novel dual responsive alginate-based magnetic nanogels for onco-theranostics. Carbohyd
Polym 204:32–41. https ://doi.org/10.1016/j.carbp ol.2018.09.084
239. Li W, Xue B, Shi K, Qu Y, Chu B, Qian Z (2019) Magnetic iron oxide nanoparticles/10-hydroxy
camptothecin co-loaded nanogel for enhanced photothermal-chemo therapy. Appl Mater Today
14:84–95. https ://doi.org/10.1016/j.apmt.2018.11.008
240. Sun W, Yang J, Zhu J, Zhou Y, Li J, Zhu X, Shen M, Zhang G, Shi X (2016) Immobilization of
iron oxide nanoparticles within alginate nanogels for enhanced MR imaging applications. Biomater Sci 4(10):1422–1430. https ://doi.org/10.1039/c6bm0 0370b
241. Hao X, Xu B, Chen H, Wang X, Zhang J, Guo R, Shi X, Cao X (2019) Stem cell-mediated
delivery of nanogels loaded with ultrasmall iron oxide nanoparticles for enhanced tumor MR
imaging. Nanoscale 11(11):4904–4910. https ://doi.org/10.1039/c8nr1 0490e
242. Hwang J, Lee E, Kim J, Seo Y, Lee KH, Hong JW, Gilad AA, Park H, Choi J (2016) Effective
delivery of immunosuppressive drug molecules by silica coated iron oxide nanoparticles. Colloids Surf B 142:290–296. https ://doi.org/10.1016/j.colsu rfb.2016.01.040
243. Monaco I, Arena F, Biffi S, Locatelli E, Bortot B, La Cava F, Marini GM, Severini GM, Terreno
E, Comes Franchini M (2017) Synthesis of lipophilic core-shell Fe 3 O 4 @SiO 2 @Au nanoparticles and polymeric entrapment into nanomicelles: a novel nanosystem for in vivo active targeting and magnetic resonance-photoacoustic dual imaging. Bioconjug Chem 28(5):1382–1390.
https ://doi.org/10.1021/acs.bioco njche m.7b000 76
244. Guisasola E, Asín L, Beola L, de la Fuente JM, Baeza A, Vallet-Regí M (2018) Beyond traditional hyperthermia: in vivo cancer treatment with magnetic-responsive mesoporous silica
nanocarriers. ACS Appl Mater Interfaces 10(15):12518–12525. https ://doi.org/10.1021/acsam
i.8b023 98
245. Hurley KR, Ring HL, Etheridge M, Zhang J, Gao Z, Shao Q, Klein ND, Szlag VM, Chung C,
Reineke TM, Garwood M, Bischof JC, Haynes CL (2016) Predictable heating and positive MRI
contrast from a mesoporous silica-coated iron oxide nanoparticle. Mol Pharm 13(7):2172–2183.
https ://doi.org/10.1021/acs.molph armac eut.5b008 66
246. Park W, Yang HN, Ling D, Yim H, Kim KS, Hyeon T, Na K, Park KH (2014) Multi-modal
transfection agent based on monodisperse magnetic nanoparticles for stem cell gene delivery and tracking. Biomaterials 35(25):7239–7247. https ://doi.org/10.1016/j.bioma teria
ls.2014.05.010
247. Lassenberger A, Bixner O, Gruenewald T, Lichtenegger H, Zirbs R, Reimhult E (2016) Evaluation
of high-yield purification methods on monodisperse PEG-grafted iron oxide nanoparticles. Langmuir 32(17):4259–4269. https ://doi.org/10.1021/acs.langm uir.6b009 19
248. Pernia Leal M, Rivera-Fernández S, Franco JM, Pozo D, de la Fuente JM, García-Martín ML
(2015) Long-circulating PEGylated manganese ferrite nanoparticles for MRI-based molecular
imaging. Nanoscale 7(5):2050–2059. https ://doi.org/10.1039/C4NR0 5781C
249. Pernia Leal M, Caro C, García-Martín ML (2017) Shedding light on zwitterionic magnetic nanoparticles: limitations for in vivo applications. Nanoscale 9(24):8176–8184. https ://doi.org/10.1039/
C7NR0 1607G
250. Leal MP, Muñoz-Hernández C, Berry CC, García-Martín ML (2015) In vivo pharmacokinetics of
T2 contrast agents based on iron oxide nanoparticles: optimization of blood circulation times. RSC
Adv 5(94):76883–76891. https ://doi.org/10.1039/C5RA1 5680G
87
Reprinted from the journal
Topics in Current Chemistry (2020) 378:40
234. Zheng XC, Ren W, Zhang S, Zhong T, Duan XC, Yin YF, Xu MQ, Hao YL, Li ZT, Li H, Liu
M, Li ZY, Zhang X (2018) The theranostic efficiency of tumor-specific, pH-responsive, peptidemodified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles. Int J
Nanomed 13:1495–1504. https ://doi.org/10.2147/IJN.S1570 82
235. Caro C, García-Martín ML, Pernia Leal M (2017) Manganese-based nanogels as pH switches
for magnetic resonance imaging. Biomacromol 18(5):1617–1623. https ://doi.org/10.1021/acs.
bioma c.7b002 24
236. Riedinger A, Pernia Leal M, Deka SR, George C, Franchini IR, Falqui A, Cingolani R, Pellegrino T (2011) "nanohybrids" based on pH-responsive hydrogels and inorganic nanoparticles
for drug delivery and sensor applications. Nano Lett 11(8):3136–3141
237. Jalili NA, Jaiswal MK, Peak CW, Cross LM, Gaharwar AK (2017) Injectable nanoengineered
stimuli-responsive hydrogels for on-demand and localized therapeutic delivery. Nanoscale
9(40):15379–15389. https ://doi.org/10.1039/c7nr0 2327h
238. Peng N, Ding X, Wang Z, Cheng Y, Gong Z, Xu X, Gao X, Cai Q, Huang S, Liu Y (2019)
Novel dual responsive alginate-based magnetic nanogels for onco-theranostics. Carbohyd
Polym 204:32–41. https ://doi.org/10.1016/j.carbp ol.2018.09.084
239. Li W, Xue B, Shi K, Qu Y, Chu B, Qian Z (2019) Magnetic iron oxide nanoparticles/10-hydroxy
camptothecin co-loaded nanogel for enhanced photothermal-chemo therapy. Appl Mater Today
14:84–95. https ://doi.org/10.1016/j.apmt.2018.11.008
240. Sun W, Yang J, Zhu J, Zhou Y, Li J, Zhu X, Shen M, Zhang G, Shi X (2016) Immobilization of
iron oxide nanoparticles within alginate nanogels for enhanced MR imaging applications. Biomater Sci 4(10):1422–1430. https ://doi.org/10.1039/c6bm0 0370b
241. Hao X, Xu B, Chen H, Wang X, Zhang J, Guo R, Shi X, Cao X (2019) Stem cell-mediated
delivery of nanogels loaded with ultrasmall iron oxide nanoparticles for enhanced tumor MR
imaging. Nanoscale 11(11):4904–4910. https ://doi.org/10.1039/c8nr1 0490e
242. Hwang J, Lee E, Kim J, Seo Y, Lee KH, Hong JW, Gilad AA, Park H, Choi J (2016) Effective
delivery of immunosuppressive drug molecules by silica coated iron oxide nanoparticles. Colloids Surf B 142:290–296. https ://doi.org/10.1016/j.colsu rfb.2016.01.040
243. Monaco I, Arena F, Biffi S, Locatelli E, Bortot B, La Cava F, Marini GM, Severini GM, Terreno
E, Comes Franchini M (2017) Synthesis of lipophilic core-shell Fe 3 O 4 @SiO 2 @Au nanoparticles and polymeric entrapment into nanomicelles: a novel nanosystem for in vivo active targeting and magnetic resonance-photoacoustic dual imaging. Bioconjug Chem 28(5):1382–1390.
https ://doi.org/10.1021/acs.bioco njche m.7b000 76
244. Guisasola E, Asín L, Beola L, de la Fuente JM, Baeza A, Vallet-Regí M (2018) Beyond traditional hyperthermia: in vivo cancer treatment with magnetic-responsive mesoporous silica
nanocarriers. ACS Appl Mater Interfaces 10(15):12518–12525. https ://doi.org/10.1021/acsam
i.8b023 98
245. Hurley KR, Ring HL, Etheridge M, Zhang J, Gao Z, Shao Q, Klein ND, Szlag VM, Chung C,
Reineke TM, Garwood M, Bischof JC, Haynes CL (2016) Predictable heating and positive MRI
contrast from a mesoporous silica-coated iron oxide nanoparticle. Mol Pharm 13(7):2172–2183.
https ://doi.org/10.1021/acs.molph armac eut.5b008 66
246. Park W, Yang HN, Ling D, Yim H, Kim KS, Hyeon T, Na K, Park KH (2014) Multi-modal
transfection agent based on monodisperse magnetic nanoparticles for stem cell gene delivery and tracking. Biomaterials 35(25):7239–7247. https ://doi.org/10.1016/j.bioma teria
ls.2014.05.010
247. Lassenberger A, Bixner O, Gruenewald T, Lichtenegger H, Zirbs R, Reimhult E (2016) Evaluation
of high-yield purification methods on monodisperse PEG-grafted iron oxide nanoparticles. Langmuir 32(17):4259–4269. https ://doi.org/10.1021/acs.langm uir.6b009 19
248. Pernia Leal M, Rivera-Fernández S, Franco JM, Pozo D, de la Fuente JM, García-Martín ML
(2015) Long-circulating PEGylated manganese ferrite nanoparticles for MRI-based molecular
imaging. Nanoscale 7(5):2050–2059. https ://doi.org/10.1039/C4NR0 5781C
249. Pernia Leal M, Caro C, García-Martín ML (2017) Shedding light on zwitterionic magnetic nanoparticles: limitations for in vivo applications. Nanoscale 9(24):8176–8184. https ://doi.org/10.1039/
C7NR0 1607G
250. Leal MP, Muñoz-Hernández C, Berry CC, García-Martín ML (2015) In vivo pharmacokinetics of
T2 contrast agents based on iron oxide nanoparticles: optimization of blood circulation times. RSC
Adv 5(94):76883–76891. https ://doi.org/10.1039/C5RA1 5680G
87
Reprinted from the journal