1 3
Topics in Current Chemistry (2020) 378:13
developed based on the magnetic behavior of MNPs and the special recognition
properties of DNA.
The appropriate selection of the delivery vector is a key factor in drug and gene
delivery systems. DNA molecules and their interaction with the surface of MNPs
should be carefully designed taking into acount the the final purpose and all the
aspects related to the host cell environment. Future perspectives in vaccination routines will probably include DNA vaccine involving nanoparticles as a novel method
to generate antigen-specific antibodies and cell-mediated immunity. However, many
aspects still need to be optimized, such as the nanoparticle–DNA vaccine efficiency
and cell viability, together with their complete clinical assays in human subjects to
validate immunogenicity.
Compliance with ethical standards
Conflict of interest The authors declare no conflict of interest.
References
1. Jeevanandam J, Barhoum A, Chan YS et al (2018) Review on nanoparticles and nanostructured
materials: history, sources, toxicity and regulations. Beilstein J Nanotechnol 9:1050–1074. https ://
doi.org/10.3762/bjnan o.9.98
2. Ahsan MA, Jabbari V, Islam MT et al (2019) Sustainable synthesis and remarkable adsorption
capacity of MOF/graphene oxide and MOF/CNT based hybrid nanocomposites for the removal
of Bisphenol A from water. Sci Total Environ 673:306–317. https ://doi.org/10.1016/j.scito
tenv.2019.03.219
3. Ahsan MA, Jabbari V, Imam MA et al (2020) Nanoscale nickel metal organic framework decorated
over graphene oxide and carbon nanotubes for water remediation. Sci Total Environ 698:134214.
https ://doi.org/10.1016/j.scito tenv.2019.13421 4
4. Ahsan MA, Deemer E, Fernandez-Delgado O et al (2019) Fe nanoparticles encapsulated in MOFderived carbon for the reduction of 4-nitrophenol and methyl orange in water. Catal Commun
130:105753. https ://doi.org/10.1016/j.catco m.2019.10575 3
5. Ahsan MA, Fernandez-Delgado O, Deemer E et al (2019) Carbonization of Co-BDC MOF results
in magnetic C@Co nanoparticles that catalyze the reduction of methyl orange and 4-nitrophenol in
water. J Mol Liq 290:111059. https ://doi.org/10.1016/j.molli q.2019.11105 9
6. Ahsan MA, Jabbari V, El-Gendy AA et al (2019) Ultrafast catalytic reduction of environmental
pollutants in water via MOF-derived magnetic Ni and Cu nanoparticles encapsulated in porous
carbon. Appl Surf Sci 497:143608. https ://doi.org/10.1016/j.apsus c.2019.14360 8
7. Franco A, Cebrián-García S, Rodríguez-Padrón D et al (2018) Encapsulated laccases as effective
electrocatalysts for oxygen reduction reactions. ACS Sustain Chem Eng 6:11058–11062. https ://
doi.org/10.1021/acssu schem eng.8b025 29
8. Cova CM, Zuliani A, Puente Santiago AR et al (2018) Microwave-assisted preparation of Ag/Ag 2 S
carbon hybrid structures from pig bristles as efficient HER catalysts. J Mater Chem A 6:21516–
21523. https ://doi.org/10.1039/C8TA0 6417B
9. Ostovar S, Franco A, Puente-Santiago AR et al (2018) Efficient mechanochemical bifunctional nanocatalysts for the conversion of isoeugenol to vanillin. Front Chem 6:1–7. https ://doi.
org/10.3389/fchem .2018.00077
10. Rodríguez-Padrón D, Puente-Santiago AR, Balu AM et al (2019) Environmental catalysis: present
and future. ChemCatChem 11:18–38. https ://doi.org/10.1002/cctc.20180 1248
11. Feng S, Li D, Low Z et al (2017) ALD-seeded hydrothermally-grown Ag/ZnO nanorod PTFE
membrane as efficient indoor air filter. J Memb Sci 531:86–93. https ://doi.org/10.1016/j.memsc
i.2017.02.042
39
Reprinted from the journal
Topics in Current Chemistry (2020) 378:13
developed based on the magnetic behavior of MNPs and the special recognition
properties of DNA.
The appropriate selection of the delivery vector is a key factor in drug and gene
delivery systems. DNA molecules and their interaction with the surface of MNPs
should be carefully designed taking into acount the the final purpose and all the
aspects related to the host cell environment. Future perspectives in vaccination routines will probably include DNA vaccine involving nanoparticles as a novel method
to generate antigen-specific antibodies and cell-mediated immunity. However, many
aspects still need to be optimized, such as the nanoparticle–DNA vaccine efficiency
and cell viability, together with their complete clinical assays in human subjects to
validate immunogenicity.
Compliance with ethical standards
Conflict of interest The authors declare no conflict of interest.
References
1. Jeevanandam J, Barhoum A, Chan YS et al (2018) Review on nanoparticles and nanostructured
materials: history, sources, toxicity and regulations. Beilstein J Nanotechnol 9:1050–1074. https ://
doi.org/10.3762/bjnan o.9.98
2. Ahsan MA, Jabbari V, Islam MT et al (2019) Sustainable synthesis and remarkable adsorption
capacity of MOF/graphene oxide and MOF/CNT based hybrid nanocomposites for the removal
of Bisphenol A from water. Sci Total Environ 673:306–317. https ://doi.org/10.1016/j.scito
tenv.2019.03.219
3. Ahsan MA, Jabbari V, Imam MA et al (2020) Nanoscale nickel metal organic framework decorated
over graphene oxide and carbon nanotubes for water remediation. Sci Total Environ 698:134214.
https ://doi.org/10.1016/j.scito tenv.2019.13421 4
4. Ahsan MA, Deemer E, Fernandez-Delgado O et al (2019) Fe nanoparticles encapsulated in MOFderived carbon for the reduction of 4-nitrophenol and methyl orange in water. Catal Commun
130:105753. https ://doi.org/10.1016/j.catco m.2019.10575 3
5. Ahsan MA, Fernandez-Delgado O, Deemer E et al (2019) Carbonization of Co-BDC MOF results
in magnetic C@Co nanoparticles that catalyze the reduction of methyl orange and 4-nitrophenol in
water. J Mol Liq 290:111059. https ://doi.org/10.1016/j.molli q.2019.11105 9
6. Ahsan MA, Jabbari V, El-Gendy AA et al (2019) Ultrafast catalytic reduction of environmental
pollutants in water via MOF-derived magnetic Ni and Cu nanoparticles encapsulated in porous
carbon. Appl Surf Sci 497:143608. https ://doi.org/10.1016/j.apsus c.2019.14360 8
7. Franco A, Cebrián-García S, Rodríguez-Padrón D et al (2018) Encapsulated laccases as effective
electrocatalysts for oxygen reduction reactions. ACS Sustain Chem Eng 6:11058–11062. https ://
doi.org/10.1021/acssu schem eng.8b025 29
8. Cova CM, Zuliani A, Puente Santiago AR et al (2018) Microwave-assisted preparation of Ag/Ag 2 S
carbon hybrid structures from pig bristles as efficient HER catalysts. J Mater Chem A 6:21516–
21523. https ://doi.org/10.1039/C8TA0 6417B
9. Ostovar S, Franco A, Puente-Santiago AR et al (2018) Efficient mechanochemical bifunctional nanocatalysts for the conversion of isoeugenol to vanillin. Front Chem 6:1–7. https ://doi.
org/10.3389/fchem .2018.00077
10. Rodríguez-Padrón D, Puente-Santiago AR, Balu AM et al (2019) Environmental catalysis: present
and future. ChemCatChem 11:18–38. https ://doi.org/10.1002/cctc.20180 1248
11. Feng S, Li D, Low Z et al (2017) ALD-seeded hydrothermally-grown Ag/ZnO nanorod PTFE
membrane as efficient indoor air filter. J Memb Sci 531:86–93. https ://doi.org/10.1016/j.memsc
i.2017.02.042
39
Reprinted from the journal