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Topics in Current Chemistry (2020) 378:12
NHS
N-hydroxysuccinimide
NPs
Nanoparticles
OA
Octanoic acid
pACC
Pediatric adrenocortical carcinoma
PDVB
Polydivinylbenzene
PEDOT:PSS Poly(3,4-ethylenedioxythiophene) polystyrene sulfonate
PEG
Polyethylene glycol
PEI
Polyethyleneimine
PPy
Polypyrrole
PSA
Prostate-specific antigen
PVA
Polyvinylalcohol
PVP
Polyvinylpyrrolidone
RGO
Reduced graphene oxide
RIL
Rilpivirine
RSD
Relative standard deviation
SAM
Self-assembled monolayer
SPR
Surface plasmon resonance
t B
Brownian relaxation time
t N
Neel relaxation time
TOAB
Tetraoctylammonium bromide
TOPO
Tri-n-octyl phosphine oxide
Tris
Tris(hydroxymethyl)aminomethane
WP
Whatman filter paper
ZnONRs
Zinc oxide nanorods
ΔG
Variation of Gibbs free energy
1 Introduction
Nanoscience and nanotechnology have allowed major breakthroughs in the development and use of new devices. Nanoparticles (NPs) have played an important role
in the design of new materials for application in areas related to medicine [1, 2],
water treatment [3, 4], electrochemical and optical sensing [5], catalysis [6–11] and
electrocatalysis [12, 13]. Their outstanding position in current chemistry is due to
the numerous advantages they confer, including biocompatibility and ease of functionalization [14], along with the possibility to make biosensors with increased sensitivity, reproducibility and reduced assay times [15, 16]. Among the many nanosystems now available, gold and silver NPs are the most well known, and possess
a wide variety of interesting optical and electrochemical properties [17–20]. Likewise, iron oxide NPs have become widely employed because of their magnetic and
electrochemical properties [21–24]. The excellent properties of NPs can be boosted
by conjugation with biomolecules, allowing exploitation of the natural specificity
of the biological component, while the NP scaffold provides increased stability and
frequently improves the biological properties of the biomolecule as compared to its
native state [25–29]. The wide variety of methodologies used to conjugate biomolecules to NPs guarantees innumerable applications of the bioconjugates obtained.
95
Reprinted from the journal
Topics in Current Chemistry (2020) 378:12
NHS
N-hydroxysuccinimide
NPs
Nanoparticles
OA
Octanoic acid
pACC
Pediatric adrenocortical carcinoma
PDVB
Polydivinylbenzene
PEDOT:PSS Poly(3,4-ethylenedioxythiophene) polystyrene sulfonate
PEG
Polyethylene glycol
PEI
Polyethyleneimine
PPy
Polypyrrole
PSA
Prostate-specific antigen
PVA
Polyvinylalcohol
PVP
Polyvinylpyrrolidone
RGO
Reduced graphene oxide
RIL
Rilpivirine
RSD
Relative standard deviation
SAM
Self-assembled monolayer
SPR
Surface plasmon resonance
t B
Brownian relaxation time
t N
Neel relaxation time
TOAB
Tetraoctylammonium bromide
TOPO
Tri-n-octyl phosphine oxide
Tris
Tris(hydroxymethyl)aminomethane
WP
Whatman filter paper
ZnONRs
Zinc oxide nanorods
ΔG
Variation of Gibbs free energy
1 Introduction
Nanoscience and nanotechnology have allowed major breakthroughs in the development and use of new devices. Nanoparticles (NPs) have played an important role
in the design of new materials for application in areas related to medicine [1, 2],
water treatment [3, 4], electrochemical and optical sensing [5], catalysis [6–11] and
electrocatalysis [12, 13]. Their outstanding position in current chemistry is due to
the numerous advantages they confer, including biocompatibility and ease of functionalization [14], along with the possibility to make biosensors with increased sensitivity, reproducibility and reduced assay times [15, 16]. Among the many nanosystems now available, gold and silver NPs are the most well known, and possess
a wide variety of interesting optical and electrochemical properties [17–20]. Likewise, iron oxide NPs have become widely employed because of their magnetic and
electrochemical properties [21–24]. The excellent properties of NPs can be boosted
by conjugation with biomolecules, allowing exploitation of the natural specificity
of the biological component, while the NP scaffold provides increased stability and
frequently improves the biological properties of the biomolecule as compared to its
native state [25–29]. The wide variety of methodologies used to conjugate biomolecules to NPs guarantees innumerable applications of the bioconjugates obtained.
95
Reprinted from the journal