new crystal structures with the incomplete data that come with using the DAC. This
was a particular challenge due to the low symmetry of the known ambient pressure
form (P1) [1]. Real-space structure solution packages such as DASH and FOX were
Fig. 11 Chemical diagrams for some pharmaceutical materials investigated using pressure.
(I) chlorothiazide; (II) chlorpropamide; (III) dalcetrapib; (IV) tolazamide; (V) ibuprofen;
(VI) indomethacin; (VII) fluconazole; (VIII) paracetamol
Crystallography Under High Pressures
169