Preface
We present in this volume an updated collection of reference data and rules
for the interpretation of spectra obtained with the spectroscopic methods most
important to the structure elucidation of organic compounds: NMR spectroscopy
( 1 H, 13 C, 15 N, 19 F, 29 Si, and 31 P), mass spectrometry (EI-MS and ESI-MS/MS),
and IR, Raman and UV/Vis spectroscopy. The basic idea is that a simultaneous
application of several of these techniques is much more powerful than even the
most sophisticated analysis of only one kind of spectrum. The ongoing success of
our combined approach corroborates its utility.
This new edition contains numerous new data added to existing tables and
figures. Additionally, we extended the scope of this volume taking into account new
developments in instrumentation.
We added novel collections of reference data for the interpretation of 15 N and
29 Si NMR spectra. The careful selection of relevant information from across the
literature seems to be unique in these fields.
An important recent development is the routine MS/MS analysis after soft
ionization (mainly ESI and MALDI). For this volume, we supplemented the existing
fragmentation rules for EI by rules for MS/MS analysis after soft ionization.
We thank Dr. Csaba Szántay und Áron Szigetvári (Spectroscopic Research
Department, Gedeon Richter AG, Budapest/Hungary) for critically reviewing the
new section on 15 N NMR.
In spite of great efforts and many checks to eliminate errors, it is likely that some
mistakes and inconsistencies remain. We would like to encourage our readers to
contact us with comments and suggestions.
Zürich and Minneapolis, August 2020
V
We present in this volume an updated collection of reference data and rules
for the interpretation of spectra obtained with the spectroscopic methods most
important to the structure elucidation of organic compounds: NMR spectroscopy
( 1 H, 13 C, 15 N, 19 F, 29 Si, and 31 P), mass spectrometry (EI-MS and ESI-MS/MS),
and IR, Raman and UV/Vis spectroscopy. The basic idea is that a simultaneous
application of several of these techniques is much more powerful than even the
most sophisticated analysis of only one kind of spectrum. The ongoing success of
our combined approach corroborates its utility.
This new edition contains numerous new data added to existing tables and
figures. Additionally, we extended the scope of this volume taking into account new
developments in instrumentation.
We added novel collections of reference data for the interpretation of 15 N and
29 Si NMR spectra. The careful selection of relevant information from across the
literature seems to be unique in these fields.
An important recent development is the routine MS/MS analysis after soft
ionization (mainly ESI and MALDI). For this volume, we supplemented the existing
fragmentation rules for EI by rules for MS/MS analysis after soft ionization.
We thank Dr. Csaba Szántay und Áron Szigetvári (Spectroscopic Research
Department, Gedeon Richter AG, Budapest/Hungary) for critically reviewing the
new section on 15 N NMR.
In spite of great efforts and many checks to eliminate errors, it is likely that some
mistakes and inconsistencies remain. We would like to encourage our readers to
contact us with comments and suggestions.
Zürich and Minneapolis, August 2020
V