279
19 F Chemical Shifts of CHF 2 Groups (δ in ppm)
19 F Chemical Shifts of CH 2 F Groups (δ in ppm)
19 F Chemical Shifts of CF 2 R 2 , CHFR 2 , and CFR 3 (δ in ppm)
Substituent
δ
–H
-144
–CH 3
-110
–CH 2 CH 3
-120
–CH 2 CH 2 CH 3
-117
–CH 2 –phenyl
-115
–CF 3
-141
–CF 2 CF 3
-138
–cyclohexyl
-126
Substituent
δ
–CCl 3
-122
–phenyl
-111
–O–CH 3
-88
–O–CF 3
-86
–C– – – N
-120
–S–phenyl
-121
–COOH
-127
–P(CF 3 ) 2
-126
Substituent
δ
–H
-268
–CH 3
-212
–CH 2 CH 3
-212
–CH 2 CH 2 CH 3
-219
–CH 2 CH 2 CH 2 CH 3
-219
–CH 2 OH
-226
–CH 2 –phenyl
-216
–CF 3
-241
–CF 2 CF 3
-243
Substituent
δ
–CCl 3
-198
–CH=CH 2
-216
–C– – – CH
-218
–phenyl
-206
–C– – – N
-251
–CO–phenyl
-226
–COOH
-229
–COO –
-218
Substituent R
CF 2 R 2
CHFR 2
CFR 3
–CH 3
-85
-165
-131
–CH 2 CH 3
-92
-183
-156
–CF 3
-132
-77
-189
–phenyl
-89
-167
-127
–Cl
-7
-81
0
6.2 19 F NMR Spectroscopy