N
X
C
O
N
S
Hal
Solvents
Natural
Products
P Si
C
C
C C
C
C
214
5 1 H NMR
1 H Chemical Shifts and Coupling Constants of Cyclic Ethers (δ in
ppm, J in Hz)
In derivatives:
2 J gem 5–6
3 J cis 4.5
3 J trans 3.1
Throughout:
J cis > J trans
2.54
2.78
3.07
4.73
2.72
3.34
1.47
4.31
4.63
6.34
6.17
7.89
7.77
3.96
4.64
4.63
6.34
6.43
6.38
1.85
1.98
2.66
7.56
6.31
4.95
2.58
5.89
O
O CH 3
H
H
H
O
O
O
O
O
3.67
2.87
1.92
N
H
O
3.88
2.57
S
O
O
O
O
O
O
O
O
O
a
a
a
a
a
a
a
a
a
e
e
d
b
b
b
b
d
d
c
d
c
c
c
b
b
c
c
d
d
b
b
b
c
c
d
3 J ab 5.2
3 J bc 4.2
3 J bd 3.3
2 J cd 4.2
3 J ab 6.2
4 J ac 2.0
3 J bc 3.8
4 J bd 0.6
3 J ab 7.0
4 J ac 1.7
4 J ae 1.5
3 J bc 3.4
3 J ab 5.0
4 J ac 2.4
5 J ad 1.2
3 J bc 6.3
4 J bd 1.5
3 J cd 9.4
3 J ab 6.0
5 J ac 0.3
4 J ad 2.7
4 J bc 1.1
2 J a,gem -5.8
2 J b,gem -11.0
3 J cis
8.7
3 J trans
6.6
| 4 J ac | <0.3
3 J ab,cis 8.3
3 J ab,trans 10.7
3 J bc
2.5
4 J bd
2.6
3 J cd
2.6
3 J ab
1.6
4 J ac
-2.5
4 J ad,cis 7.1
4 J ad,trans 4.6
3 J bc
6.3
a
b
c
CDCl 3 DMSO
a 3.74
3.60
b 1.85
1.76
CDCl 3 DMSO
a 3.65
3.53
b 1.57
1.47
c 1.64
1.58
CDCl 3 DMSO D 2 O
3.71
3.57
3.75