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79. Zhu W, Wang Y, Yao Y, Chang J, Graber HL, Barbour RL (1997) Iterative total least-squares
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81. Yu DF, Fessler JA (1998) Edge-preserving tomographic reconstruction with nonlocal regularization. IEEE Trans Med Imaging 21(2):159–173
82. Darne C, Lu Y, Sevick-Muraca EM (2014) Small animal fluorescence and bioluminescence
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83. Han D, Tian J, Zhu S, Feng J, Qin C, Zhang B, Yang X (2010) A fast reconstruction algorithm
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84. Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V
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85. Ntziachristos V (2010) Going deeper than microscopy: the optical imaging frontier in biology.
Nat Methods 7(8):603–614
86. Ale A, Ermolayev V, Herzog E, Cohrs C, de Angelis MH, Ntziachristos V (2012) FMT-XCT:
in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed
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87. Mohajerani P, Hipp A, Willner M, Marschner M, Trajkovic-Arsic M, Ma X, Burton NC,
Klemm U, Radrich K, Ermolayev V, Tzoumas S, Siveke JT, Bech M, Pfeiffer F,
Ntziachristos V (2014) FMT-PCCT: hybrid fluorescence molecular tomography-x-ray
phase-contrast CT imaging of mouse models. IEEE Trans Med Imaging 33(7):1434–1446
88. Mohajerani P, Ntziachristos V (2016) An inversion scheme for hybrid fluorescence molecular
tomography using a fuzzy inference system. IEEE Trans Med Imaging 35(2):381–390
89. Berninger MT, Mohajerani P, Kimm M, Masius S, Ma X, Wildgruber M, Haller B, Anton M,
Imhoff AB, Ntziachristos V, Henning TD, Meier R (2017) Fluorescence molecular tomography of DiR-labeled mesenchymal stem cell implants for osteochondral defect repair in rabbit
knees. Eur Radiol 27(3):1105–1113
90. Allard M, Côté D, Davidson L, Dazai J, Henkelman RM (2007) Combined magnetic
resonance and bioluminescence imaging of live mice. J Biomed Opt 12(3):034018
91. Cao X, Yang J, Gao Y, Guo Y, Wu G, Shen D (2017) Dual-core steered non-rigid registration
for multi-modal images via bi-directional image synthesis. Med Image Anal 41:18–31
92. Phillips EH, Di Achille P, Bersi MR, Humphrey JD, Goergen CJ (2017) Multi-modality
imaging enables detailed hemodynamic simulations in dissecting aneurysms in mice.
IEEE Trans Med Imaging 36(6):1297–1305
93. Chen ZY, Wang YX, Yang F, Lin Y, Zhou QL, Liao YY (2014) New researches and
application progress of commonly used optical molecular imaging technology. Biomed Res
Int 2014:429198
94. Zhang Y, Zhang B, Liu F, Luo J, Bai J (2014) In vivo tomographic imaging with fluorescence
and MRI using tumor-targeted dual-labeled nanoparticles. Int J Nanomedicine 9:33–41
95. Wang K, Chi CW, Hu ZH, Liu MH, Hui H, Shang WT, Peng D, Zhang S, Ye JZ, Liu HX,
Tian J (2015) Optical molecular imaging frontiers in oncology: the pursuit of accuracy and
sensitivity. Engineering 1(3):309–323
Fluorescence Molecular Imaging of Medicinal Chemistry in Cancer
29
reconstruction for spectrally-resolved bioluminescence tomography with sparse a priori information. Opt Express 17(10):8062–8080
78. An Y, Liu J, Zhang G, Jiang S, Ye J, Chi C, Tian J (2017) Compactly supported radial basis
function-based meshless method for photon propagation model of fluorescence molecular
tomography. IEEE Trans Med Imaging 36(2):366–373
79. Zhu W, Wang Y, Yao Y, Chang J, Graber HL, Barbour RL (1997) Iterative total least-squares
image reconstruction algorithm for optical tomography by the conjugate gradient method.
J Opt Soc Am A Opt Image Sci Vis 14(4):799–807
80. Paulsen KD, Jiang H (1996) Enhanced frequency-domain optical image reconstruction in
tissues through total-variation minimization. Appl Optics 35(19):3447–3458
81. Yu DF, Fessler JA (1998) Edge-preserving tomographic reconstruction with nonlocal regularization. IEEE Trans Med Imaging 21(2):159–173
82. Darne C, Lu Y, Sevick-Muraca EM (2014) Small animal fluorescence and bioluminescence
tomography: a review of approaches, algorithms and technology update. Phys Med Biol 59(1):
R1–R64
83. Han D, Tian J, Zhu S, Feng J, Qin C, Zhang B, Yang X (2010) A fast reconstruction algorithm
for fluorescence molecular tomography with sparsity regularization. Opt Express 18
(8):8630–8646
84. Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V
(2005) Volumetric tomography of fluorescent proteins through small animals in vivo.
Proc Natl Acad Sci U S A 102(51):18252–18257
85. Ntziachristos V (2010) Going deeper than microscopy: the optical imaging frontier in biology.
Nat Methods 7(8):603–614
86. Ale A, Ermolayev V, Herzog E, Cohrs C, de Angelis MH, Ntziachristos V (2012) FMT-XCT:
in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed
tomography. Nat Methods 9(6):615–620
87. Mohajerani P, Hipp A, Willner M, Marschner M, Trajkovic-Arsic M, Ma X, Burton NC,
Klemm U, Radrich K, Ermolayev V, Tzoumas S, Siveke JT, Bech M, Pfeiffer F,
Ntziachristos V (2014) FMT-PCCT: hybrid fluorescence molecular tomography-x-ray
phase-contrast CT imaging of mouse models. IEEE Trans Med Imaging 33(7):1434–1446
88. Mohajerani P, Ntziachristos V (2016) An inversion scheme for hybrid fluorescence molecular
tomography using a fuzzy inference system. IEEE Trans Med Imaging 35(2):381–390
89. Berninger MT, Mohajerani P, Kimm M, Masius S, Ma X, Wildgruber M, Haller B, Anton M,
Imhoff AB, Ntziachristos V, Henning TD, Meier R (2017) Fluorescence molecular tomography of DiR-labeled mesenchymal stem cell implants for osteochondral defect repair in rabbit
knees. Eur Radiol 27(3):1105–1113
90. Allard M, Côté D, Davidson L, Dazai J, Henkelman RM (2007) Combined magnetic
resonance and bioluminescence imaging of live mice. J Biomed Opt 12(3):034018
91. Cao X, Yang J, Gao Y, Guo Y, Wu G, Shen D (2017) Dual-core steered non-rigid registration
for multi-modal images via bi-directional image synthesis. Med Image Anal 41:18–31
92. Phillips EH, Di Achille P, Bersi MR, Humphrey JD, Goergen CJ (2017) Multi-modality
imaging enables detailed hemodynamic simulations in dissecting aneurysms in mice.
IEEE Trans Med Imaging 36(6):1297–1305
93. Chen ZY, Wang YX, Yang F, Lin Y, Zhou QL, Liao YY (2014) New researches and
application progress of commonly used optical molecular imaging technology. Biomed Res
Int 2014:429198
94. Zhang Y, Zhang B, Liu F, Luo J, Bai J (2014) In vivo tomographic imaging with fluorescence
and MRI using tumor-targeted dual-labeled nanoparticles. Int J Nanomedicine 9:33–41
95. Wang K, Chi CW, Hu ZH, Liu MH, Hui H, Shang WT, Peng D, Zhang S, Ye JZ, Liu HX,
Tian J (2015) Optical molecular imaging frontiers in oncology: the pursuit of accuracy and
sensitivity. Engineering 1(3):309–323
Fluorescence Molecular Imaging of Medicinal Chemistry in Cancer
29