Complete resection of enhancing tumor
(CRET), 36
Compton camera XFCT, 139
Computed tomography (CT), 34
contrast agents, 149
Confocal laser endomicroscopy (CLEM), 207
Copper nanoclusters (CuNCs), thiolateprotected, 194
Coumarins, 4, 186
CS790AM, 174
Cyan fluorescent protein (CFP), 165
Cyanine 7-azide, 217
Cyanines (Cy), 4, 35
Cyclooxygenase-2 (COX-2), 9
Cysteine (Cys), 43
D
DCDHF-β-gal, 197
DCM-β-gal, 189
Deoxyhemoglobin, 82
D1ER, 160
Diagnostic imaging, 203
Difluoroboron dipyrromethene (BODIPY),
4, 19, 35–38, 45, 47
Diketopyrrolopyrrole (DPP), 93
Disease, diagnosis, 33
Donor–acceptor chromophore-based
nanoparticle (DAP), 89
Dopamine, 162, 172
Doxorubicin, 20
Drug biodistribution, 17
Drug discovery, 3, 7, 15, 150
DsRed, 154, 158, 162, 163
Dye-doped inorganic nanoparticles, 70
Dyes, small-molecule, 81
E
Endoscopy, 205–210
autofluorescence (AFE), 206
chromo-, 205, 207
digital, 205
gastro-, 205, 207
induced fluorescence (IFE), 207
intravascular, 208
Raman, 209
white light (WLE), 204, 206
Epithelial cell adhesion molecule (EPCAM),
214
ERα, 16
Erbium (Er), 135
Estrogen receptor (ER), 8
Europium (Eu), 136
Excited-state intramolecular proton transfer
(ESIPT), 189
F
Facilitated hexose transporters (Gluts), 8
FD-1080, 89
Finite difference method (FDM), 14
Finite element method (FEM), 14
5-Aminolevulinic acid (5-ALA), 35, 36, 42,
207, 212
Flavin adenine dinucleotide (FAD), 35, 39
Fluorescein isothiocyanate (FITC), 4
Fluoresceins, 186
Fluorescence imaging, 33
dyes, 12, 149, 190
in vivo, 55
probes, 33
prodrug conjugates, 19
Fluorescence lifetime imaging microscopy
(FLIM), 39
Fluorescence molecular tomography
(FMT), 12
Fluorescence resonance energy transfer
(FRET), 149–173
sensors, 161, 165, 169
Fluorescent molecular imaging (FMI), 1
Fluorescent proteins, 149
circularly permuted, 163
pH-responsive, 158
Fluorodeoxyglucose, 216
Fluorophores, 4, 34–47, 81–120, 169,
188, 214
near-infrared, 188, 207, 214
organic, 33, 39, 56, 70
Folate receptor, 9
4-Aminonaphthalimide, 43
4-Hydroxyl-N-butyl-1,8-naphthalimide–β-gal
(NI–β-gal), 188
4-Nitrophenyl-β-D-galactopyranoside (NPGal),
196
FPNM, 17
Fructose transporter (GLUT5), 8
G
Gadolinium oxide, 1345
Gd 2 O 2 S:Eu (GOSE), 136
Gemcitabine, 20
Genetically encoded sensors (GES), 154
Glutathione (GSH), 43, 194
GLUT5 transporter, 8
226
Index
(CRET), 36
Compton camera XFCT, 139
Computed tomography (CT), 34
contrast agents, 149
Confocal laser endomicroscopy (CLEM), 207
Copper nanoclusters (CuNCs), thiolateprotected, 194
Coumarins, 4, 186
CS790AM, 174
Cyan fluorescent protein (CFP), 165
Cyanine 7-azide, 217
Cyanines (Cy), 4, 35
Cyclooxygenase-2 (COX-2), 9
Cysteine (Cys), 43
D
DCDHF-β-gal, 197
DCM-β-gal, 189
Deoxyhemoglobin, 82
D1ER, 160
Diagnostic imaging, 203
Difluoroboron dipyrromethene (BODIPY),
4, 19, 35–38, 45, 47
Diketopyrrolopyrrole (DPP), 93
Disease, diagnosis, 33
Donor–acceptor chromophore-based
nanoparticle (DAP), 89
Dopamine, 162, 172
Doxorubicin, 20
Drug biodistribution, 17
Drug discovery, 3, 7, 15, 150
DsRed, 154, 158, 162, 163
Dye-doped inorganic nanoparticles, 70
Dyes, small-molecule, 81
E
Endoscopy, 205–210
autofluorescence (AFE), 206
chromo-, 205, 207
digital, 205
gastro-, 205, 207
induced fluorescence (IFE), 207
intravascular, 208
Raman, 209
white light (WLE), 204, 206
Epithelial cell adhesion molecule (EPCAM),
214
ERα, 16
Erbium (Er), 135
Estrogen receptor (ER), 8
Europium (Eu), 136
Excited-state intramolecular proton transfer
(ESIPT), 189
F
Facilitated hexose transporters (Gluts), 8
FD-1080, 89
Finite difference method (FDM), 14
Finite element method (FEM), 14
5-Aminolevulinic acid (5-ALA), 35, 36, 42,
207, 212
Flavin adenine dinucleotide (FAD), 35, 39
Fluorescein isothiocyanate (FITC), 4
Fluoresceins, 186
Fluorescence imaging, 33
dyes, 12, 149, 190
in vivo, 55
probes, 33
prodrug conjugates, 19
Fluorescence lifetime imaging microscopy
(FLIM), 39
Fluorescence molecular tomography
(FMT), 12
Fluorescence resonance energy transfer
(FRET), 149–173
sensors, 161, 165, 169
Fluorescent molecular imaging (FMI), 1
Fluorescent proteins, 149
circularly permuted, 163
pH-responsive, 158
Fluorodeoxyglucose, 216
Fluorophores, 4, 34–47, 81–120, 169,
188, 214
near-infrared, 188, 207, 214
organic, 33, 39, 56, 70
Folate receptor, 9
4-Aminonaphthalimide, 43
4-Hydroxyl-N-butyl-1,8-naphthalimide–β-gal
(NI–β-gal), 188
4-Nitrophenyl-β-D-galactopyranoside (NPGal),
196
FPNM, 17
Fructose transporter (GLUT5), 8
G
Gadolinium oxide, 1345
Gd 2 O 2 S:Eu (GOSE), 136
Gemcitabine, 20
Genetically encoded sensors (GES), 154
Glutathione (GSH), 43, 194
GLUT5 transporter, 8
226
Index