199
tetrasaccharide were observed: C 17 H 26 N 3 O 4
+
at m/z 336.1242, B 1
+
at m/z 260.0739,
[B 1  – H 2 O]
+
at m/z 242.0709,
2,5
A 1
+
at m/z 230.0719, C 11 H 16 N 3 O 2
+
at m/z 222.0670
and [C 1  – C 5 H 11 NO 2 ]
+
at m/z 159.0486 (Fig. 11.8). Accordingly, the fragmentation
of the carbohydrate portion allowed to confirm its structure and contributed to
Fig. 11.8 (a) MALDI-TOF/TOF-MS/MS spectra of the glycated peptide ALK*AWSVAR (Lys
265) at m/z 1951.0130. (b) Different product ions involving the fragmentation of the carbohydrate
hapten observed during the MALDI-TOF/TOF-MS/MS analysis of the glycated peptide
ALK*AWSVAR (Lys 235) at m / z 1951.0130 [69]
11 Defense Against Biological Terrorism: Vaccines and Their Characterizations