90. Zhang M, Dong JF, Jin HH, Sun LN, Xu MJ (2011) Ultraviolet-B-induced flavonoid accumulation in Betula pendula leaves is dependent upon nitrate reductase-mediated nitric oxide
signaling. Tree Physiol 31(8):798–807. https://doi.org/10.1093/treephys/tpr070
91. Krasylenko YA, Yemets AI, Sheremet YA, Blume YB (2012) Nitric oxide as a critical factor
for perception of UV-B irradiation by microtubules in Arabidopsis. Physiol Plant 145(4):
505–515. https://doi.org/10.1111/j.1399-3054.2011.01530.x
92. Tossi V, Lombardo C, Cassia R, Lamattina L (2012) Nitric oxide and flavonoids are systemically induced by UV-B in maize leaves. Plant Sci 103:193–194. https://doi.org/10.1016/j.
plantsci.2012.05.012
93. Cui JX, Zhou YH, Ding JG, Xia XJ, Shi KAI, Chen SC, . . . Yu JQ (2011) Role of nitric oxide in
hydrogen peroxide-dependent induction of abiotic stress tolerance by brassinosteroids in cucumber. Plant Cell Environ 34(2):347–358. https://doi.org/10.1111/j.1365-3040.2010. 02248.x
94. Xu MJ (2007) Nitric oxide: a potential key point of the signaling network leading to plant
secondary metabolite biosynthesis. Prog Nat Sci 17(12):1397–1404
95. Zhang B, Zheng LP, Wang JW (2012) Nitric oxide elicitation for secondary metabolite
production in cultured plant cells. Appl Microbiol Biotechnol 93(2):455–466. https://doi.
org/10.1007/s00253-011-3658-8
96. Xu M, Dong J (2005) Elicitor-induced nitric oxide burst is essential for triggering
catharanthine synthesis in Catharanthus roseus suspension cells. Appl Microbiol Biotechnol
67(1):40–44. https://doi.org/10.1007/s00253-004-1737-9
97. ZhangJ XM (2006) Effects of nitric oxide and methyljasmonate on the baicalin production and
cell growth in suspension cultures of Scutellaria baicalensis. Chin Sci Bull 23:374–379
98. Liao W, Xiao H, Zhang M (2009) Role and relationship of nitric oxide and hydrogen peroxide
in adventitious root development of marigold. Acta Physiol Plant 31(6):1279–1289. https://
doi.org/10.1007/s11738-009-0367-3
99. Xu MJ, Dong JF (2008) Synergistic action between jasmonic acid and nitric oxide in inducing
matrine accumulation of Sophora flavescens suspension cells. J Integr Plant Biol 50(1):
92–101. https://doi.org/10.1111/j.1744-7909.2007.00570.x
100. Wu SJ, Qi JL, Zhang WJ, Liu SH, Xiao FH, Zhang MS, . . . Shen HG (2008) Nitric oxide
regulates shikonin formation in suspension-cultured Onosma paniculatum cells. Plant Cell
Physiol 50(1):118–128. https://doi.org/10.1093/pcp/pcn178
101. Ai J, Zhou B, Jia J (2009) The effects of NO and AgNO 3 on cell growth and salidroside
synthesis in Rhodiola sachalinensis A. Bor. cell suspension culture. J Microbial Biochem
Technol 1(1):11–14
102. Zheng LP, Guo YT, Wang JW, Tan RX (2008) Nitric oxide potentiates oligosaccharideinduced artemisinin production in Artemisia annua hairy roots. J Integr Plant Biol 50(1):
49–55. https://doi.org/10.1111/j.1744-7909.2007.00589.x
103. Wang Y, Dai C, Zhao Y, Peng Y (2011) Fungal endophyte-induced volatile oil accumulation in
Atractylodes lancea plantlets is mediated by nitric oxide, salicylic acid and hydrogen peroxide.
Process Biochem 46(3):730–735. https://doi.org/10.1016/j.procbio.2010.11.020
104. Fang F, Dai C, Wang Y (2009) Role of nitric oxide and hydrogen peroxide in the essential
oil increasing of suspension cells from Atractylodes lancea induced by endophytic fungal
Cunninghamella sp. AL4 elicitor. Sheng Wu Gong Cheng Xue Bao 25(10):1490–1496
105. Xu MJ, Dong JF, Zhu MY (2005) Nitric oxide mediates the fungal elicitor-induced hypericin
production of Hypericum perforatum cell suspension cultures through a jasmonic-acid-dependent signal pathway. Plant Physiol 139(2):991–998. https://doi.org/10.1104/pp.105.066407
106. Hao G, Du X, Zhao F, Shi R, Wang J (2009) Role of nitric oxide in UV-B-induced activation of
PAL and stimulation of flavonoid biosynthesis in Ginkgo biloba callus. Plant Cell Tissue Org
Cult 97(2):175–185. https://doi.org/10.1007/s11240-009-9513-2
107. Qu Y, Feng H, Wang Y, Zhang M, Cheng J, Wang X, An L (2006) Nitric oxide functions as a
signal in ultraviolet-B induced inhibition of pea stems elongation. Plant Sci 170(5):994–1000.
https://doi.org/10.1016/j.plantsci.2006.01.003
108. Li DW, Li ML, Liu Y, Zu YG (2015) Effect of nitric oxide on the secondary metabolites of
Taxus chinensis var. mairei under UV-B exposure. Adv Mater Res 1073:114–117. Trans Tech
Publications. https://doi.org/10.4028/www.scientific.net/AMR.1073-1076.114
25 Nitric Oxide as a Signal in Inducing Secondary Metabolites During Plant Stress
619
signaling. Tree Physiol 31(8):798–807. https://doi.org/10.1093/treephys/tpr070
91. Krasylenko YA, Yemets AI, Sheremet YA, Blume YB (2012) Nitric oxide as a critical factor
for perception of UV-B irradiation by microtubules in Arabidopsis. Physiol Plant 145(4):
505–515. https://doi.org/10.1111/j.1399-3054.2011.01530.x
92. Tossi V, Lombardo C, Cassia R, Lamattina L (2012) Nitric oxide and flavonoids are systemically induced by UV-B in maize leaves. Plant Sci 103:193–194. https://doi.org/10.1016/j.
plantsci.2012.05.012
93. Cui JX, Zhou YH, Ding JG, Xia XJ, Shi KAI, Chen SC, . . . Yu JQ (2011) Role of nitric oxide in
hydrogen peroxide-dependent induction of abiotic stress tolerance by brassinosteroids in cucumber. Plant Cell Environ 34(2):347–358. https://doi.org/10.1111/j.1365-3040.2010. 02248.x
94. Xu MJ (2007) Nitric oxide: a potential key point of the signaling network leading to plant
secondary metabolite biosynthesis. Prog Nat Sci 17(12):1397–1404
95. Zhang B, Zheng LP, Wang JW (2012) Nitric oxide elicitation for secondary metabolite
production in cultured plant cells. Appl Microbiol Biotechnol 93(2):455–466. https://doi.
org/10.1007/s00253-011-3658-8
96. Xu M, Dong J (2005) Elicitor-induced nitric oxide burst is essential for triggering
catharanthine synthesis in Catharanthus roseus suspension cells. Appl Microbiol Biotechnol
67(1):40–44. https://doi.org/10.1007/s00253-004-1737-9
97. ZhangJ XM (2006) Effects of nitric oxide and methyljasmonate on the baicalin production and
cell growth in suspension cultures of Scutellaria baicalensis. Chin Sci Bull 23:374–379
98. Liao W, Xiao H, Zhang M (2009) Role and relationship of nitric oxide and hydrogen peroxide
in adventitious root development of marigold. Acta Physiol Plant 31(6):1279–1289. https://
doi.org/10.1007/s11738-009-0367-3
99. Xu MJ, Dong JF (2008) Synergistic action between jasmonic acid and nitric oxide in inducing
matrine accumulation of Sophora flavescens suspension cells. J Integr Plant Biol 50(1):
92–101. https://doi.org/10.1111/j.1744-7909.2007.00570.x
100. Wu SJ, Qi JL, Zhang WJ, Liu SH, Xiao FH, Zhang MS, . . . Shen HG (2008) Nitric oxide
regulates shikonin formation in suspension-cultured Onosma paniculatum cells. Plant Cell
Physiol 50(1):118–128. https://doi.org/10.1093/pcp/pcn178
101. Ai J, Zhou B, Jia J (2009) The effects of NO and AgNO 3 on cell growth and salidroside
synthesis in Rhodiola sachalinensis A. Bor. cell suspension culture. J Microbial Biochem
Technol 1(1):11–14
102. Zheng LP, Guo YT, Wang JW, Tan RX (2008) Nitric oxide potentiates oligosaccharideinduced artemisinin production in Artemisia annua hairy roots. J Integr Plant Biol 50(1):
49–55. https://doi.org/10.1111/j.1744-7909.2007.00589.x
103. Wang Y, Dai C, Zhao Y, Peng Y (2011) Fungal endophyte-induced volatile oil accumulation in
Atractylodes lancea plantlets is mediated by nitric oxide, salicylic acid and hydrogen peroxide.
Process Biochem 46(3):730–735. https://doi.org/10.1016/j.procbio.2010.11.020
104. Fang F, Dai C, Wang Y (2009) Role of nitric oxide and hydrogen peroxide in the essential
oil increasing of suspension cells from Atractylodes lancea induced by endophytic fungal
Cunninghamella sp. AL4 elicitor. Sheng Wu Gong Cheng Xue Bao 25(10):1490–1496
105. Xu MJ, Dong JF, Zhu MY (2005) Nitric oxide mediates the fungal elicitor-induced hypericin
production of Hypericum perforatum cell suspension cultures through a jasmonic-acid-dependent signal pathway. Plant Physiol 139(2):991–998. https://doi.org/10.1104/pp.105.066407
106. Hao G, Du X, Zhao F, Shi R, Wang J (2009) Role of nitric oxide in UV-B-induced activation of
PAL and stimulation of flavonoid biosynthesis in Ginkgo biloba callus. Plant Cell Tissue Org
Cult 97(2):175–185. https://doi.org/10.1007/s11240-009-9513-2
107. Qu Y, Feng H, Wang Y, Zhang M, Cheng J, Wang X, An L (2006) Nitric oxide functions as a
signal in ultraviolet-B induced inhibition of pea stems elongation. Plant Sci 170(5):994–1000.
https://doi.org/10.1016/j.plantsci.2006.01.003
108. Li DW, Li ML, Liu Y, Zu YG (2015) Effect of nitric oxide on the secondary metabolites of
Taxus chinensis var. mairei under UV-B exposure. Adv Mater Res 1073:114–117. Trans Tech
Publications. https://doi.org/10.4028/www.scientific.net/AMR.1073-1076.114
25 Nitric Oxide as a Signal in Inducing Secondary Metabolites During Plant Stress
619