97. Beresovsky D, Hadas O, Livne A, Sukenik A, Kaplan A, Carmeli S (2006) Toxins and
biologically active secondary metabolites of Microcystis sp. isolated from Lake Kinneret. Isr
J Chem 46:79–87
98. Jaja-Chimedza A, Sanchez K, Gantar M, Gibbs P, Schmale M, Berry JP (2017) Carotenoid
glycosides from cyanobacteria are teratogenic in the zebrafish (Danio rerio) embryo model.
Chemosphere 174:478–489
99. Micallef ML, Sharma D, Bunn BM, Gerwick L, Viswanathan R, Moffitt MC (2014) Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution
of indole-isonitrile biosynthesis from cyanobacteria. BMC Microbiol 14:213–213
100. Volk R-B, Mundt S (2007) Cytotoxic and non-cytotoxic exometabolites of the cyanobacterium
Nostoc insulare. J Appl Phycol 19:55–62
101. Volk R-B (2007) Studies on culture age versus exometabolite production in batch cultures of
the cyanobacterium Nostoc insulare. J Appl Phycol 19:491–495
102. Hirata K, Yoshitomi S, Dwi S, Iwabe O, Mahakhant A, Polchai J, Miyamoto K (2003)
Bioactivities of nostocine a produced by a freshwater cyanobacterium Nostoc spongiaeforme
TISTR 8169. J Biosci Bioeng 95:512–517
103. Doan NT, Rickards RW, Rothschild JM, Smith GD, Doan NT, Rickards RW, Rothschild JM,
Smith GD (2000) Allelopathic actions of the alkaloid 12-epi-hapalindole E isonitrile and
calothrixin A from cyanobacteria of the genera Fischerella and Calothrix. J Appl Phycol
12:409–416
104. Rickards RW, Rothschild JM, Willis AC, de Chazal NM, Kirk J, Kirk K, Saliba KJ, Smith
GD (1999) Calothrixins A and B, novel pentacyclic metabolites from Calothrix
cyanobacteria with potent activity against malaria parasites and human cancer cells. Tetrahedron 55:13513–13520
105. Etchegaray A, Rabello E, Dieckmann R, Moon DH, Fiore MF, von Döhren H, Tsai SM,
Neilan BA (2004) Algicide production by the filamentous cyanobacterium Fischerella sp.
CENA 19. J Appl Phycol 16:237–243
106. Walton K, Gantar M, Gibbs PDL, Schmale MC, Berry JP (2014) Indole alkaloids from
Fischerella inhibit vertebrate development in the zebrafish (Danio rerio) embryo model.
Toxins 6:3568–3581
107. Abarzua S, Jakubowski S, Eckert S, Fuchs P (1999) Biotechnological investigation for the
prevention of marine biofouling II. Blue-green algae as potential producers of biogenic agents
for the growth inhibition of microfouling organisms. Bot Mar 42:459–465
108. Gleason FK, Paulson JL (1984) Site of action of the natural algicide, cyanobacterin, in the
blue-green alga, Synechococcus sp. Arch Microbiol 138:273–277
109. Mason CP, Edwards KR, Carlson RE, Pignatello J, Gleason FK, Wood JM (1982) Isolation of
chlorine-containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni.
Science (New York) 215:400–402
110. Jaja-Chimedza A, Gantar M, Gibbs PDL, Schmale MC, Berry JP (2012) Polymethoxy-1alkenes from Aphanizomenon ovalisporum inhibit vertebrate development in the zebrafish
(Danio rerio) embryo model. Mar Drugs 10:2322–2336
111. Sukenik A, Eshkol R, Livne A, Hadas O, Rom M, Tchernov D, Vardi A, Kaplan A (2002)
Inhibition of growth and photosynthesis of the dinoflagellate Peridinium gatunense by
Microcystis sp. (cyanobacteria): a novel allelopathic mechanism. Limnol Oceanogr
47:1656–1663
112. Pflugmacher S, Aulhorn M, Grimm B (2007) Influence of a cyanobacterial crude extract
containing microcystin-LR on the physiology and antioxidative defence systems of different
spinach variants. New Phytol 175:482–489
113. Ma Z, Fang T, Thring RW, Li Y, Yu H, Zhou Q, Zhao M (2015) Toxic and non-toxic strains of
Microcystis aeruginosa induce temperature dependent allelopathy toward growth and photosynthesis of Chlorella vulgaris. Harmful Algae 48:21–29
114. Zhang TT, Liu L, Yang XH, Zhang SJ, Xia WT, Li C (2014) Allelopathic control of freshwater
phytoplankton by the submerged macrophyte Najas minor All. Acta Ecol Sin 34:351–355
14 Effects of Cyanobacterial Secondary Metabolites on Phytoplankton Community. . . 343
biologically active secondary metabolites of Microcystis sp. isolated from Lake Kinneret. Isr
J Chem 46:79–87
98. Jaja-Chimedza A, Sanchez K, Gantar M, Gibbs P, Schmale M, Berry JP (2017) Carotenoid
glycosides from cyanobacteria are teratogenic in the zebrafish (Danio rerio) embryo model.
Chemosphere 174:478–489
99. Micallef ML, Sharma D, Bunn BM, Gerwick L, Viswanathan R, Moffitt MC (2014) Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution
of indole-isonitrile biosynthesis from cyanobacteria. BMC Microbiol 14:213–213
100. Volk R-B, Mundt S (2007) Cytotoxic and non-cytotoxic exometabolites of the cyanobacterium
Nostoc insulare. J Appl Phycol 19:55–62
101. Volk R-B (2007) Studies on culture age versus exometabolite production in batch cultures of
the cyanobacterium Nostoc insulare. J Appl Phycol 19:491–495
102. Hirata K, Yoshitomi S, Dwi S, Iwabe O, Mahakhant A, Polchai J, Miyamoto K (2003)
Bioactivities of nostocine a produced by a freshwater cyanobacterium Nostoc spongiaeforme
TISTR 8169. J Biosci Bioeng 95:512–517
103. Doan NT, Rickards RW, Rothschild JM, Smith GD, Doan NT, Rickards RW, Rothschild JM,
Smith GD (2000) Allelopathic actions of the alkaloid 12-epi-hapalindole E isonitrile and
calothrixin A from cyanobacteria of the genera Fischerella and Calothrix. J Appl Phycol
12:409–416
104. Rickards RW, Rothschild JM, Willis AC, de Chazal NM, Kirk J, Kirk K, Saliba KJ, Smith
GD (1999) Calothrixins A and B, novel pentacyclic metabolites from Calothrix
cyanobacteria with potent activity against malaria parasites and human cancer cells. Tetrahedron 55:13513–13520
105. Etchegaray A, Rabello E, Dieckmann R, Moon DH, Fiore MF, von Döhren H, Tsai SM,
Neilan BA (2004) Algicide production by the filamentous cyanobacterium Fischerella sp.
CENA 19. J Appl Phycol 16:237–243
106. Walton K, Gantar M, Gibbs PDL, Schmale MC, Berry JP (2014) Indole alkaloids from
Fischerella inhibit vertebrate development in the zebrafish (Danio rerio) embryo model.
Toxins 6:3568–3581
107. Abarzua S, Jakubowski S, Eckert S, Fuchs P (1999) Biotechnological investigation for the
prevention of marine biofouling II. Blue-green algae as potential producers of biogenic agents
for the growth inhibition of microfouling organisms. Bot Mar 42:459–465
108. Gleason FK, Paulson JL (1984) Site of action of the natural algicide, cyanobacterin, in the
blue-green alga, Synechococcus sp. Arch Microbiol 138:273–277
109. Mason CP, Edwards KR, Carlson RE, Pignatello J, Gleason FK, Wood JM (1982) Isolation of
chlorine-containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni.
Science (New York) 215:400–402
110. Jaja-Chimedza A, Gantar M, Gibbs PDL, Schmale MC, Berry JP (2012) Polymethoxy-1alkenes from Aphanizomenon ovalisporum inhibit vertebrate development in the zebrafish
(Danio rerio) embryo model. Mar Drugs 10:2322–2336
111. Sukenik A, Eshkol R, Livne A, Hadas O, Rom M, Tchernov D, Vardi A, Kaplan A (2002)
Inhibition of growth and photosynthesis of the dinoflagellate Peridinium gatunense by
Microcystis sp. (cyanobacteria): a novel allelopathic mechanism. Limnol Oceanogr
47:1656–1663
112. Pflugmacher S, Aulhorn M, Grimm B (2007) Influence of a cyanobacterial crude extract
containing microcystin-LR on the physiology and antioxidative defence systems of different
spinach variants. New Phytol 175:482–489
113. Ma Z, Fang T, Thring RW, Li Y, Yu H, Zhou Q, Zhao M (2015) Toxic and non-toxic strains of
Microcystis aeruginosa induce temperature dependent allelopathy toward growth and photosynthesis of Chlorella vulgaris. Harmful Algae 48:21–29
114. Zhang TT, Liu L, Yang XH, Zhang SJ, Xia WT, Li C (2014) Allelopathic control of freshwater
phytoplankton by the submerged macrophyte Najas minor All. Acta Ecol Sin 34:351–355
14 Effects of Cyanobacterial Secondary Metabolites on Phytoplankton Community. . . 343