38. WHO (2003) Cyanobacterial toxins: Microcystin-LR in drinking-water. In: World Health
Organization (ed) Background document for preparation of WHO Guidelines for drinkingwater quality. World Health Organization, Geneva
39. Bratbak G, Thingstad T (1985) Phytoplankton-bacteria interactions: an apparent paradox?
Analysis of a model system with both competition and commensalism. Mar Ecol Prog Ser
25:23–30
40. Fish SA, Codd GA (1994) Bioactive compound production by thermophilic and thermotolerant cyanobacteria (blue-green algae). World J Microbiol Biotechnol 10:338–341
41. Berry JP, Gantar M, Gawley RE, Wang M, Rein KS (2004) Pharmacology and toxicology of
pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the
Florida Everglades. Comp Biochem Physiol Part C: Toxicol Pharmacol 139:231–238
42. Volk R-B, Furkert FH (2006) Antialgal, antibacterial and antifungal activity of two metabolites
produced and excreted by cyanobacteria during growth. Microbiol Res 161:180–186
43. Dias F, Antunes JT, Ribeiro T, Azevedo J, Vasconcelos V, Leão PN (2017) Cyanobacterial
allelochemicals but not cyanobacterial cells markedly reduce microbial community diversity.
Front Microbiol 8:1495
44. Scheffer M, Hosper SH, Meijer ML, Moss B, Jeppesen E (1993) Alternative equilibria in
shallow lakes. Trends Ecol Evol 8:275–279
45. Hilt S, Gross EM (2008) Can allelopathically active submerged macrophytes stabilise clearwater states in shallow lakes? Basic Appl Ecol 9:422–432
46. Hilt S (2015) Regime shifts between macrophytes and phytoplankton–concepts beyond
shallow lakes, unravelling stabilizing mechanisms and practical consequences. Limnetica
34:467–480
47. Mohamed ZA (2017) Macrophytes-cyanobacteria allelopathic interactions and their implications for water resources management – a review. Limnologica 63:122–132
48. Zheng GL, Xu RB, Chang XX, Hilt S, Wu C (2013) Cyanobacteria can allelopathically inhibit
submerged macrophytes: effects of Microcystis aeruginosa extracts and exudates on
Potamogeton malaianus. Aquat Bot 109:1–7
49. Xu RB, Wu F, Hilt S, Wu C, Wang XL, Chang XX (2015) Recovery limitation of endangered
Ottelia acuminata by allelopathic interaction with cyanobacteria. Aquat Ecol 49:333–342
50. Chislock MF, Sarnelle O, Jernigan LM, Wilson AE (2013) Do high concentrations of
microcystin prevent Daphnia control of phytoplankton? Water Res 47:1961–1970
51. Leitão E, Ger KA, Panosso R (2018) Selective grazing by a tropical copepod (Notodiaptomus
iheringi) facilitates Microcystis dominance. Front Microbiol 9:301
52. Scotti T, Mimura M, Wakano JY (2015) Avoiding toxic prey may promote harmful algal
blooms. Ecol Complex 21:157–165
53. Jungmann D (1995) Isolation, purification, and characterization of new Daphnia-toxic compound from axenic Microcystis flos-aquae strain PCC7806. J Chem Ecol 21:1665–1676
54. Rohrlack T, Christoffersen K, Hansen PE, Zhang W, Czarnecki O, Henning M, Fastner J,
Erhard M, Neilan BA, Kaebernick M (2003) Isolation, characterization, and quantitative
analysis of microviridin J, a new Microcystis metabolite toxic to Daphnia. J Chem Ecol
29:1757–1770
55. Wiegand C, Peuthert A, Pflugmacher S, Carmeli S (2002) Effects of microcin SF608 and
microcystin-LR, two cyanotobacterial compounds produced by Microcystis sp., on aquatic
organisms. Environ Toxicol 17:400–406
56. Gustafsson S, Hansson L-A (2004) Development of tolerance against toxic cyanobacteria in
Daphnia. Aquat Ecol 38:37–44
57. Smutná M, Priebojová J, Večerková J, Hilscherová K (2017) Retinoid-like compounds
produced by phytoplankton affect embryonic development of Xenopus laevis. Ecotoxicol
Environ Saf 138:32–38
58. Zi J, Pan X, MacIsaac HJ, Yang J, Xu R, Chen S, Chang X (2018) Cyanobacteria blooms
induce embryonic heart failure in an endangered fish species. Aquat Toxicol 194:78–85
340
Y. Pei et al.
Organization (ed) Background document for preparation of WHO Guidelines for drinkingwater quality. World Health Organization, Geneva
39. Bratbak G, Thingstad T (1985) Phytoplankton-bacteria interactions: an apparent paradox?
Analysis of a model system with both competition and commensalism. Mar Ecol Prog Ser
25:23–30
40. Fish SA, Codd GA (1994) Bioactive compound production by thermophilic and thermotolerant cyanobacteria (blue-green algae). World J Microbiol Biotechnol 10:338–341
41. Berry JP, Gantar M, Gawley RE, Wang M, Rein KS (2004) Pharmacology and toxicology of
pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the
Florida Everglades. Comp Biochem Physiol Part C: Toxicol Pharmacol 139:231–238
42. Volk R-B, Furkert FH (2006) Antialgal, antibacterial and antifungal activity of two metabolites
produced and excreted by cyanobacteria during growth. Microbiol Res 161:180–186
43. Dias F, Antunes JT, Ribeiro T, Azevedo J, Vasconcelos V, Leão PN (2017) Cyanobacterial
allelochemicals but not cyanobacterial cells markedly reduce microbial community diversity.
Front Microbiol 8:1495
44. Scheffer M, Hosper SH, Meijer ML, Moss B, Jeppesen E (1993) Alternative equilibria in
shallow lakes. Trends Ecol Evol 8:275–279
45. Hilt S, Gross EM (2008) Can allelopathically active submerged macrophytes stabilise clearwater states in shallow lakes? Basic Appl Ecol 9:422–432
46. Hilt S (2015) Regime shifts between macrophytes and phytoplankton–concepts beyond
shallow lakes, unravelling stabilizing mechanisms and practical consequences. Limnetica
34:467–480
47. Mohamed ZA (2017) Macrophytes-cyanobacteria allelopathic interactions and their implications for water resources management – a review. Limnologica 63:122–132
48. Zheng GL, Xu RB, Chang XX, Hilt S, Wu C (2013) Cyanobacteria can allelopathically inhibit
submerged macrophytes: effects of Microcystis aeruginosa extracts and exudates on
Potamogeton malaianus. Aquat Bot 109:1–7
49. Xu RB, Wu F, Hilt S, Wu C, Wang XL, Chang XX (2015) Recovery limitation of endangered
Ottelia acuminata by allelopathic interaction with cyanobacteria. Aquat Ecol 49:333–342
50. Chislock MF, Sarnelle O, Jernigan LM, Wilson AE (2013) Do high concentrations of
microcystin prevent Daphnia control of phytoplankton? Water Res 47:1961–1970
51. Leitão E, Ger KA, Panosso R (2018) Selective grazing by a tropical copepod (Notodiaptomus
iheringi) facilitates Microcystis dominance. Front Microbiol 9:301
52. Scotti T, Mimura M, Wakano JY (2015) Avoiding toxic prey may promote harmful algal
blooms. Ecol Complex 21:157–165
53. Jungmann D (1995) Isolation, purification, and characterization of new Daphnia-toxic compound from axenic Microcystis flos-aquae strain PCC7806. J Chem Ecol 21:1665–1676
54. Rohrlack T, Christoffersen K, Hansen PE, Zhang W, Czarnecki O, Henning M, Fastner J,
Erhard M, Neilan BA, Kaebernick M (2003) Isolation, characterization, and quantitative
analysis of microviridin J, a new Microcystis metabolite toxic to Daphnia. J Chem Ecol
29:1757–1770
55. Wiegand C, Peuthert A, Pflugmacher S, Carmeli S (2002) Effects of microcin SF608 and
microcystin-LR, two cyanotobacterial compounds produced by Microcystis sp., on aquatic
organisms. Environ Toxicol 17:400–406
56. Gustafsson S, Hansson L-A (2004) Development of tolerance against toxic cyanobacteria in
Daphnia. Aquat Ecol 38:37–44
57. Smutná M, Priebojová J, Večerková J, Hilscherová K (2017) Retinoid-like compounds
produced by phytoplankton affect embryonic development of Xenopus laevis. Ecotoxicol
Environ Saf 138:32–38
58. Zi J, Pan X, MacIsaac HJ, Yang J, Xu R, Chen S, Chang X (2018) Cyanobacteria blooms
induce embryonic heart failure in an endangered fish species. Aquat Toxicol 194:78–85
340
Y. Pei et al.