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Hierarchy of controlling ailment due to environmental factors is given in
Table 3.10.
Kyasanur Forest disease (monkey fever) is an exemplar of ailment of development linked with deforestation in southern part of India (Nichter 1987). In the
1950s, there was a significant increase in the human population in the Sagar taluk of
Shimoga district in the Karnataka State of India, which resulted in noteworthy
changes in the local ecosystem giving rise to conditions favoring expression of a
hidden enzootic process (Boshell 1969), and the disease, which was earlier endemic
to Karnataka state, has been detected from neighboring states as well (Chaubal
et al. 2018).
Theoretically the control of ailment due to the environmental factors may look
simple, but in reality the issues such as disasters, institutional capacity, fund availability, skills and knowledge, and corruption of country/community will guide the
end results, which are far from satisfactory. Consequently, the subsequent chapter
discusses the theory of environmental health issues and established/possible solution along with deviations in practice.
The pathogenesis (manner of development of a disease) of many ailments
involves host, genetic, and environmental factors. Apart from other health disorders,
these factors disturb the innate system besides adaptive immune systems as well as
composition of the intestinal microbiota. Epidemiologic and migration studies supporting environmental risk factors for Crohn’s disease (CD) include childhood
hygiene, air pollution, breastfeeding, smoking, diet, stress, exercise, seasonal variation, and appendectomy (surgical removal of the appendix; Dam et al. 2013).
Although several neurodegenerative (associated with loss of neuronal structure
and function) diseases have been linked to the environmental exposures, single
environmental factor accounting for a noteworthy number of cases has not been
identified. Exposure to pesticides, herbicides, fungicides, organochlorines,
organophosphates, and carbamates have been linked to Parkinson’s disease (Cannon
and Greenamyre 2011). Exposure to lead, mercury, and pesticides have all been
cited as potential risk factors for amyotrophic lateral sclerosis (ALS; Johnson and
Atchison 2009).
3 Fundamentals of Biology for Environmental and Medical Professionals
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