132
L. Schorr et al.
40. Greer, F.R., Shannon, M.: Infant methemoglobinemia: the role of dietary nitrate in food and
water. Pediatrics 116, 784–786 (2005). https://doi.org/10.1542/peds.2005-1497
41. Guidelines for Drinking-Water Quality, 4th edn.: World Health Organization, Geneva (2017)
42. Gupta, A. B.: Thiosphaera pantotropha: a sulphur bacterium capable of simultaneous
heterotrophic nitrification and aerobic denitrification. Enzyme Micro. Technol. 21(8), S.
589–595 (1997). https://doi.org/10.1016/S0141-0229(97)00070-7
43. Gupta, S.K., Gupta, C., Gupta, A.B., Seth, A.K., Bassin, J.K., Gupta, A.: Recurrent acute
respiratory tract infections in areas with high nitrate concentrations in drinking water. Environ.
Health Perspect. 108, 363–366 (2000). https://doi.org/10.1289/ehp.00108363
44. Hahn, J., Katja Becker, K.: Dimensionen der antimikrobiellen Resistenz. Nova Acta Leopold.
NF Nr. 424, 147–165 (2019)
45. Halling-Sorensen, B., Jorgensen, S.E.: The removal of nitrogen from wastewater. In: Studies
in Environmental Science, vol. 54, 1st edn., pp. 43–53. Elsevier (1993). https://doi.org/10.
1016/S0166-1116(08)70524-7
46. Härtig, E., Schiek, U., Vollack, K.U., Zumft, W.G.: Nitrate and nitrite control of respiratory
nitrate reduction in denitrifying Pseudomonas stutzeri by a two-component regulatory system
homologous to NarXL of Escherichia coli. J. Bacteriol. 181, 3658–3665 (1999)
47. Holmes, D.E., Dang, Y., Smith, J.A.: Nitrogen cycling during wastewater treatment. Adv.
Appl. Microbiol. 106, 113–192 (2019). https://doi.org/10.1016/bs.aambs.2018.10.003
48. Hossain, M.I., Paparini, A., Cord-Ruwisch, R.: Rapid adaptation of activated sludge bacteria
into a glycogen accumulating biofilm enabling anaerobic BOD uptake. Bioresour. Technol.
228, 1–8 (2017). https://doi.org/10.1016/j.biortech.2016.11.102
49. Hsu, T., Welner, D.H., Russ, Z.N., Cervantes, B., Prathuri, R.L., Adams, P.D., Dueber, J.E.:
Employing a biochemical protecting group for a sustainable indigo dyeing strategy. Nat.
Chem. Biol. 14, 256–261 (2018). https://doi.org/10.1038/nchembio.2552
50. Hutchison, Clyde, A., Chuang, R,-Y., Noskov, Vladimir, N., Assad-Garcia, N., Deerinck,
Thomas. J., Ellisman, M.H.. et al.: Design and synthesis of a minimal bacterial genome. In:
Science (New York, N.Y.), vol. 351 (6280), aad6253. (2016). https://doi.org/10.1126/science.
aad6253
51. Hwang, J.H., Oleszkiewicz, J.A.: Effect of cold-temperature shock on nitrification. Water
Environ. Res. 79, 964–968 (2007). https://doi.org/10.2175/106143007X176022
52. iGEM Team Virginia 2017; http://2017.igem.org/Team, Virginia (as of August 2020)
53. iGEM Team Marburg (2018) http://2018.igem.org/Team, Marburg (as of August 2020)
54. iGEM Foundation: iGEM Foundation. 27 Drydock Avenue, Suite 27E-230, Boston, MA
02210 (2019). https://2019.igem.org/Main_Page
55. Jetten, M.S.M., Sliekers, O., Kuypers, M., Dalsgaard, T., van Niftrik, L., Cirpus, I., van
de Pas-Schoonen, K.T., Lavik, G., Thamdrup, B., Le Paslier, D., Op den Camp, H.J.M.,
Hulth, S., Nielsen, L.P., Abma, W., Third, K., Engström, P., Kuenen, J.G., Jørgensen, B.B.,
Canfield, D., Sinninghe-Damste, J.S., Revsbech, N.P., Fuerst, J., Weissenbach, J., Wagner,
M., Schmidt, I., Schmid, M., Strous, M.: Anaerobic ammonium oxidation by marine and
freshwater planctomycete-like bacteria. Appl. Microbiol. Biotechnol. 63, 107–114 (2003).
https://doi.org/10.1007/s00253-003-1422-4
56. Kartal, B., Almeida, N.M., Maalcke, W.J., Op den Camp, H.J.M., Jetten, M.S.M., Keltjens,
J.T.: How to make a living from anaerobic ammonium oxidation. FEMS Microbiol. Rev.
37(3), 428–461 (2013). https://doi.org/10.1111/1574-6976.12014
57. Katz, L., Chen, Y.Y., Gonzalez, R., Peterson, T.C., Zhao, H., Baltz, R.H.: Synthetic biology
advances and applications in the biotechnology industry: a perspective. J. Ind. Microbiol.
Biotechnol. 45, 449 (2018). https://doi.org/10.1007/s10295-018-2056-y
58. Khosla, C., Bailey, J.E.: Characterization of the oxygen-dependent promoter of the Vitreoscilla
hemoglobin gene in Escherichia coli. J. Bacteriol. 171, 5995–6004 (1989). https://doi.org/10.
1128/jb.171.11.5995-6004.1989
59. Kim, Y., Kang, J., Shen, B., Wang, Y., He, Y., Lee, M.: Open–closed switching of synthetic
tubular pores. Nat. Commun. 6, 8650 (2015). https://doi.org/10.1038/ncomms9650
L. Schorr et al.
40. Greer, F.R., Shannon, M.: Infant methemoglobinemia: the role of dietary nitrate in food and
water. Pediatrics 116, 784–786 (2005). https://doi.org/10.1542/peds.2005-1497
41. Guidelines for Drinking-Water Quality, 4th edn.: World Health Organization, Geneva (2017)
42. Gupta, A. B.: Thiosphaera pantotropha: a sulphur bacterium capable of simultaneous
heterotrophic nitrification and aerobic denitrification. Enzyme Micro. Technol. 21(8), S.
589–595 (1997). https://doi.org/10.1016/S0141-0229(97)00070-7
43. Gupta, S.K., Gupta, C., Gupta, A.B., Seth, A.K., Bassin, J.K., Gupta, A.: Recurrent acute
respiratory tract infections in areas with high nitrate concentrations in drinking water. Environ.
Health Perspect. 108, 363–366 (2000). https://doi.org/10.1289/ehp.00108363
44. Hahn, J., Katja Becker, K.: Dimensionen der antimikrobiellen Resistenz. Nova Acta Leopold.
NF Nr. 424, 147–165 (2019)
45. Halling-Sorensen, B., Jorgensen, S.E.: The removal of nitrogen from wastewater. In: Studies
in Environmental Science, vol. 54, 1st edn., pp. 43–53. Elsevier (1993). https://doi.org/10.
1016/S0166-1116(08)70524-7
46. Härtig, E., Schiek, U., Vollack, K.U., Zumft, W.G.: Nitrate and nitrite control of respiratory
nitrate reduction in denitrifying Pseudomonas stutzeri by a two-component regulatory system
homologous to NarXL of Escherichia coli. J. Bacteriol. 181, 3658–3665 (1999)
47. Holmes, D.E., Dang, Y., Smith, J.A.: Nitrogen cycling during wastewater treatment. Adv.
Appl. Microbiol. 106, 113–192 (2019). https://doi.org/10.1016/bs.aambs.2018.10.003
48. Hossain, M.I., Paparini, A., Cord-Ruwisch, R.: Rapid adaptation of activated sludge bacteria
into a glycogen accumulating biofilm enabling anaerobic BOD uptake. Bioresour. Technol.
228, 1–8 (2017). https://doi.org/10.1016/j.biortech.2016.11.102
49. Hsu, T., Welner, D.H., Russ, Z.N., Cervantes, B., Prathuri, R.L., Adams, P.D., Dueber, J.E.:
Employing a biochemical protecting group for a sustainable indigo dyeing strategy. Nat.
Chem. Biol. 14, 256–261 (2018). https://doi.org/10.1038/nchembio.2552
50. Hutchison, Clyde, A., Chuang, R,-Y., Noskov, Vladimir, N., Assad-Garcia, N., Deerinck,
Thomas. J., Ellisman, M.H.. et al.: Design and synthesis of a minimal bacterial genome. In:
Science (New York, N.Y.), vol. 351 (6280), aad6253. (2016). https://doi.org/10.1126/science.
aad6253
51. Hwang, J.H., Oleszkiewicz, J.A.: Effect of cold-temperature shock on nitrification. Water
Environ. Res. 79, 964–968 (2007). https://doi.org/10.2175/106143007X176022
52. iGEM Team Virginia 2017; http://2017.igem.org/Team, Virginia (as of August 2020)
53. iGEM Team Marburg (2018) http://2018.igem.org/Team, Marburg (as of August 2020)
54. iGEM Foundation: iGEM Foundation. 27 Drydock Avenue, Suite 27E-230, Boston, MA
02210 (2019). https://2019.igem.org/Main_Page
55. Jetten, M.S.M., Sliekers, O., Kuypers, M., Dalsgaard, T., van Niftrik, L., Cirpus, I., van
de Pas-Schoonen, K.T., Lavik, G., Thamdrup, B., Le Paslier, D., Op den Camp, H.J.M.,
Hulth, S., Nielsen, L.P., Abma, W., Third, K., Engström, P., Kuenen, J.G., Jørgensen, B.B.,
Canfield, D., Sinninghe-Damste, J.S., Revsbech, N.P., Fuerst, J., Weissenbach, J., Wagner,
M., Schmidt, I., Schmid, M., Strous, M.: Anaerobic ammonium oxidation by marine and
freshwater planctomycete-like bacteria. Appl. Microbiol. Biotechnol. 63, 107–114 (2003).
https://doi.org/10.1007/s00253-003-1422-4
56. Kartal, B., Almeida, N.M., Maalcke, W.J., Op den Camp, H.J.M., Jetten, M.S.M., Keltjens,
J.T.: How to make a living from anaerobic ammonium oxidation. FEMS Microbiol. Rev.
37(3), 428–461 (2013). https://doi.org/10.1111/1574-6976.12014
57. Katz, L., Chen, Y.Y., Gonzalez, R., Peterson, T.C., Zhao, H., Baltz, R.H.: Synthetic biology
advances and applications in the biotechnology industry: a perspective. J. Ind. Microbiol.
Biotechnol. 45, 449 (2018). https://doi.org/10.1007/s10295-018-2056-y
58. Khosla, C., Bailey, J.E.: Characterization of the oxygen-dependent promoter of the Vitreoscilla
hemoglobin gene in Escherichia coli. J. Bacteriol. 171, 5995–6004 (1989). https://doi.org/10.
1128/jb.171.11.5995-6004.1989
59. Kim, Y., Kang, J., Shen, B., Wang, Y., He, Y., Lee, M.: Open–closed switching of synthetic
tubular pores. Nat. Commun. 6, 8650 (2015). https://doi.org/10.1038/ncomms9650