• Unveiling the presynaptic mechanism involved in vesicle release as function of
the presynaptic spike sequence.
• Decoding of the synaptic EPSP sequence as function of the presynaptic spike
sequence and its relationship with the presynaptic stimuli which determine the
sequence.
• Decoding the real integration systems which relate the information arriving
from different areas and their integration at the dendritic level in order to
produce the postsynaptic spike sequence.
• Establishing the relationship between the dendritic excitation produced by
thousands of synapses and the single synaptic event. This is necessary to
understand the real contribution of a single event and of a single presynaptic
sequence of spikes in building the postsynaptic EPSP sequence and
consequently its participation to the postsynaptic spike sequences
(postsynaptic neural code).
All these challenges are very hard, and each of them will need still years of
investigation in the field of the information processing in the brain.
Author details
Vito Di Maio* and Silvia Santillo
Institute of Applied Science and Intelligent Systems (ISASI) of CNR,
Pozzuoli (NA), Italy
*Address all correspondence to: vito.dimaio@cnr.it
© 2020 The Author(s). Licensee IntechOpen. Distributed under the terms of the Creative
Commons Attribution - NonCommercial 4.0 License (https://creativecommons.org/
licenses/by-nc/4.0/), which permits use, distribution and reproduction for
non-commercial purposes, provided the original is properly cited.
–NC
104
Advances in Neural Signal Processing
the presynaptic spike sequence.
• Decoding of the synaptic EPSP sequence as function of the presynaptic spike
sequence and its relationship with the presynaptic stimuli which determine the
sequence.
• Decoding the real integration systems which relate the information arriving
from different areas and their integration at the dendritic level in order to
produce the postsynaptic spike sequence.
• Establishing the relationship between the dendritic excitation produced by
thousands of synapses and the single synaptic event. This is necessary to
understand the real contribution of a single event and of a single presynaptic
sequence of spikes in building the postsynaptic EPSP sequence and
consequently its participation to the postsynaptic spike sequences
(postsynaptic neural code).
All these challenges are very hard, and each of them will need still years of
investigation in the field of the information processing in the brain.
Author details
Vito Di Maio* and Silvia Santillo
Institute of Applied Science and Intelligent Systems (ISASI) of CNR,
Pozzuoli (NA), Italy
*Address all correspondence to: vito.dimaio@cnr.it
© 2020 The Author(s). Licensee IntechOpen. Distributed under the terms of the Creative
Commons Attribution - NonCommercial 4.0 License (https://creativecommons.org/
licenses/by-nc/4.0/), which permits use, distribution and reproduction for
non-commercial purposes, provided the original is properly cited.
–NC
104
Advances in Neural Signal Processing