De Jong LPA, van Dijk C, Berhitoe D, Benschop HP (1993) Hydrolysis and binding of a toxic
stereoisomer of soman in plasma and tissue homogenates from rat, guinea pig and marmoset,
and in human plasma. Biochem Pharmacol 46(8):1413–1419
Devlin JP, Edwards OE, Gorham PR, Hunter NR, Pike RK, Stavric B (1977) Anatoxin-a, a toxic
alkaloid from Anabaena flos-aquae NRC-44h. Can J Chem 55(8):1367–1371
Driscoll HC, Matson SW, Sayer JM, Kroth H, Jerina DM, Brosh Jr RM (2003) Inhibition of Werner
syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both
strand-and stereoisomer-dependent. J Biol Chem 278(42):41126–41135
Duan L, Zhang Y, Wang B, Deng S, Huang J, Wang Y, Yu G (2018) Occurrence, elimination,
enantiomeric distribution and intra-day variations of chiral pharmaceuticals in major wastewater
treatment plants in Beijing, China. Environ Pollut 239:473–482
Etheridge SM (2010) Paralytic shellfish poisoning: seafood safety and human health perspectives.
Toxicon 56(2):108–122
Evans SE, Kasprzyk-Hordern B (2014) Applications of chiral chromatography coupled with mass
spectrometry in the analysis of chiral pharmaceuticals in the environment. Trends Environ Anal
Chem 1:e34–e51
Ezzariai A, Hafidi M, Khadra A, Aemig Q, El Fels L, Barret M, Merlina G, Patureau D, Pinelli E
(2018) Human and veterinary antibiotics during composting of sludge or manure: global
perspectives on persistence, degradation, and resistance genes. J Hazard Mater 359:465–481
Fawell JK, Mitchell RE, Hill RE, Everett DJ (1999) The toxicity of cyanobacterial toxins in the
mouse: II Anatoxin-a. Hum Exp Toxicol 18(3):168–173
Fiedler H, Kallenborn R, de Boer J, Sydnes L, K. (2019) The Stockholm Convention: a tool for the
global regulation of persistent organic pollutants. Chem Int 41(2):4–11
Frysinger GS, Gaines RB, Xu L, Reddy CM (2003) Resolving the unresolved complex mixture in
petroleum-contaminated sediments. Environ Sci Technol 37(8):1653–1662
Fuerhacker M (2009) EU Water Framework Directive and Stockholm Convention. Environ Sci
Pollut Res 16(1):92–97
Gao B, Zhao S, Zhang Z, Li L, Hu K, Kaziem AE, He Z, Hua X, Shi H, Wang M (2019a) A
potential biomarker of isofenphos-methyl in humans: a chiral view. Environ Int 127:694–703
Gao J, Wang F, Wang P, Jiang W, Zhang Z, Liu D, Zhou Z (2019b) Enantioselective toxic effects
and environmental behavior of ethiprole and its metabolites against Chlorella pyrenoidosa.
Environ Pollut 244:757–765
Garrison AW (2006) Probing the enantioselectivity of chiral pesticides. Environ Sci Technol 40
(1):16–23
Garrison AW, Cyterski M, Roberts KD, Burdette D, Williamson J, Avants JK (2014) Occurrences
and fate of DDT principal isomers/metabolites, DDA, and o,p
0 -DDD enantiomers in fish,
sediment and water at a DDT-impacted Superfund site. Environ Pollut 194:224–234
Gasser G, Pankratov I, Elhanany S, Werner P, Gun J, Gelman F, Lev O (2012) Field and laboratory
studies of the fate and enantiomeric enrichment of venlafaxine and O-desmethylvenlafaxine
under aerobic and anaerobic conditions. Chemosphere 88(1):98–105
Godduhn A, Duffy LK (2003) Multi-generation health risks of persistent organic pollution in the far
north: use of the precautionary approach in the Stockholm Convention. Environ Sci Policy 6
(4):341–353
Goto T, Kishi Y, Takahashi S, Hirata Y (1965) Tetrodotoxin. Tetrahedron 21(8):2059–2088
Guo F, Tang Q, Xie J, Zhao L, Liu K, Liu W (2018) Enantioseparation and identification for the
rationalization of the environmental impact of 4 polychlorinated biphenyls. Chirality 30
(4):475–483
Gupta RC (2006) Toxicology of organophosphate and carbamate compounds. Elsevier Academic,
Boston
Hamm JT, Chen CY, Birnbaum LS (2003) A mixture of dioxins, furans, and non-ortho PCBs based
upon consensus toxic equivalency factors produces dioxin-like reproductive effects. Toxicol Sci
74(1):182–191
296
10 Chirality in Environmental Toxicity and Fate Assessments
stereoisomer of soman in plasma and tissue homogenates from rat, guinea pig and marmoset,
and in human plasma. Biochem Pharmacol 46(8):1413–1419
Devlin JP, Edwards OE, Gorham PR, Hunter NR, Pike RK, Stavric B (1977) Anatoxin-a, a toxic
alkaloid from Anabaena flos-aquae NRC-44h. Can J Chem 55(8):1367–1371
Driscoll HC, Matson SW, Sayer JM, Kroth H, Jerina DM, Brosh Jr RM (2003) Inhibition of Werner
syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both
strand-and stereoisomer-dependent. J Biol Chem 278(42):41126–41135
Duan L, Zhang Y, Wang B, Deng S, Huang J, Wang Y, Yu G (2018) Occurrence, elimination,
enantiomeric distribution and intra-day variations of chiral pharmaceuticals in major wastewater
treatment plants in Beijing, China. Environ Pollut 239:473–482
Etheridge SM (2010) Paralytic shellfish poisoning: seafood safety and human health perspectives.
Toxicon 56(2):108–122
Evans SE, Kasprzyk-Hordern B (2014) Applications of chiral chromatography coupled with mass
spectrometry in the analysis of chiral pharmaceuticals in the environment. Trends Environ Anal
Chem 1:e34–e51
Ezzariai A, Hafidi M, Khadra A, Aemig Q, El Fels L, Barret M, Merlina G, Patureau D, Pinelli E
(2018) Human and veterinary antibiotics during composting of sludge or manure: global
perspectives on persistence, degradation, and resistance genes. J Hazard Mater 359:465–481
Fawell JK, Mitchell RE, Hill RE, Everett DJ (1999) The toxicity of cyanobacterial toxins in the
mouse: II Anatoxin-a. Hum Exp Toxicol 18(3):168–173
Fiedler H, Kallenborn R, de Boer J, Sydnes L, K. (2019) The Stockholm Convention: a tool for the
global regulation of persistent organic pollutants. Chem Int 41(2):4–11
Frysinger GS, Gaines RB, Xu L, Reddy CM (2003) Resolving the unresolved complex mixture in
petroleum-contaminated sediments. Environ Sci Technol 37(8):1653–1662
Fuerhacker M (2009) EU Water Framework Directive and Stockholm Convention. Environ Sci
Pollut Res 16(1):92–97
Gao B, Zhao S, Zhang Z, Li L, Hu K, Kaziem AE, He Z, Hua X, Shi H, Wang M (2019a) A
potential biomarker of isofenphos-methyl in humans: a chiral view. Environ Int 127:694–703
Gao J, Wang F, Wang P, Jiang W, Zhang Z, Liu D, Zhou Z (2019b) Enantioselective toxic effects
and environmental behavior of ethiprole and its metabolites against Chlorella pyrenoidosa.
Environ Pollut 244:757–765
Garrison AW (2006) Probing the enantioselectivity of chiral pesticides. Environ Sci Technol 40
(1):16–23
Garrison AW, Cyterski M, Roberts KD, Burdette D, Williamson J, Avants JK (2014) Occurrences
and fate of DDT principal isomers/metabolites, DDA, and o,p
0 -DDD enantiomers in fish,
sediment and water at a DDT-impacted Superfund site. Environ Pollut 194:224–234
Gasser G, Pankratov I, Elhanany S, Werner P, Gun J, Gelman F, Lev O (2012) Field and laboratory
studies of the fate and enantiomeric enrichment of venlafaxine and O-desmethylvenlafaxine
under aerobic and anaerobic conditions. Chemosphere 88(1):98–105
Godduhn A, Duffy LK (2003) Multi-generation health risks of persistent organic pollution in the far
north: use of the precautionary approach in the Stockholm Convention. Environ Sci Policy 6
(4):341–353
Goto T, Kishi Y, Takahashi S, Hirata Y (1965) Tetrodotoxin. Tetrahedron 21(8):2059–2088
Guo F, Tang Q, Xie J, Zhao L, Liu K, Liu W (2018) Enantioseparation and identification for the
rationalization of the environmental impact of 4 polychlorinated biphenyls. Chirality 30
(4):475–483
Gupta RC (2006) Toxicology of organophosphate and carbamate compounds. Elsevier Academic,
Boston
Hamm JT, Chen CY, Birnbaum LS (2003) A mixture of dioxins, furans, and non-ortho PCBs based
upon consensus toxic equivalency factors produces dioxin-like reproductive effects. Toxicol Sci
74(1):182–191
296
10 Chirality in Environmental Toxicity and Fate Assessments