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different consequences on the entire life span of an individual. Different assays are
used to check PAHs both qualitatively and quantitatively in various samples.
Keywords Polycyclic aromatic hydrocarbons · Ecosystem · Endocrine-disrupting
chemicals · Obesogens
Introduction
The endocrine system is a large network of hormones whose function is to regulate
multiple cells functions harmoniously. Hormones are needed in a very minute
amount and at a particular instant to control different functions of the body. This
complex network has numerous stimulation points and retro-action loops in chains
to set various physiological parameters including lipedema, glycemia, hydromineral regulation, etc. and physiological functions, e.g. development, growth,
reproduction, etc. at a suitable range to maintain body homeostasis and survival of
the species.
Endocrine-Disrupting Chemicals (EDCs)
Environmental contaminants that disturb hormonal system are named as endocrinedisrupting chemicals (EDCs). Scientifically, EDCs are exogenous substance or mixture that restrains or stimulates any hormonal actions. EDCs were defined by WHO
in 2002 as “an exogenous mixture or substance that changes endocrine system
function(s) and accordingly results in abnormal health issues in whole organism, or
in its descendants, or (sub)populations.” EDCs are natural or synthetic molecules
that interfere and provoke harmful dysregulation of hormonal parameters or functions which are controlled physiologically [1].
Effect of EDCs on Endocrine System
Endocrine disruptors combat and interfere with the physiology of endocrine systems (hormones), and thus results in the hazardous effects which occur for a long
time although the exposure has stopped. Endocrine disruptors have long lasting
effects on survival and can even have obvious consequences on the next generation.
According to WHO, most of potential EDCs are synthetic and are components of
numerous materials including additives or contaminants in food, pesticides, personal care products, and metals. Exposure of human beings occurs via ingestion of
EDCs contaminated food, drinking water, and dust particles, via inhalation of
A. Khan et al.
different consequences on the entire life span of an individual. Different assays are
used to check PAHs both qualitatively and quantitatively in various samples.
Keywords Polycyclic aromatic hydrocarbons · Ecosystem · Endocrine-disrupting
chemicals · Obesogens
Introduction
The endocrine system is a large network of hormones whose function is to regulate
multiple cells functions harmoniously. Hormones are needed in a very minute
amount and at a particular instant to control different functions of the body. This
complex network has numerous stimulation points and retro-action loops in chains
to set various physiological parameters including lipedema, glycemia, hydromineral regulation, etc. and physiological functions, e.g. development, growth,
reproduction, etc. at a suitable range to maintain body homeostasis and survival of
the species.
Endocrine-Disrupting Chemicals (EDCs)
Environmental contaminants that disturb hormonal system are named as endocrinedisrupting chemicals (EDCs). Scientifically, EDCs are exogenous substance or mixture that restrains or stimulates any hormonal actions. EDCs were defined by WHO
in 2002 as “an exogenous mixture or substance that changes endocrine system
function(s) and accordingly results in abnormal health issues in whole organism, or
in its descendants, or (sub)populations.” EDCs are natural or synthetic molecules
that interfere and provoke harmful dysregulation of hormonal parameters or functions which are controlled physiologically [1].
Effect of EDCs on Endocrine System
Endocrine disruptors combat and interfere with the physiology of endocrine systems (hormones), and thus results in the hazardous effects which occur for a long
time although the exposure has stopped. Endocrine disruptors have long lasting
effects on survival and can even have obvious consequences on the next generation.
According to WHO, most of potential EDCs are synthetic and are components of
numerous materials including additives or contaminants in food, pesticides, personal care products, and metals. Exposure of human beings occurs via ingestion of
EDCs contaminated food, drinking water, and dust particles, via inhalation of
A. Khan et al.