295
62. McKinlay R, Plant JA, Bell JNB, Voulvoulis N. Calculating human exposure to endocrine
disrupting pesticides via agricultural and non-agricultural exposure routes. Sci Total Environ.
2008;398(1):1–12.
63. Weber D, Davies MJ, Grune T. Determination of protein carbonyls in plasma, cell extracts,
tissue homogenates, isolated proteins: focus on sample preparation and derivatization conditions. Redox Biol. 2015;5:367–80.
64. Clasen B, Loro VL, Cattaneo R, Moraes B, Lopes T, de Avila LA, et al. Effects of the commercial formulation containing fipronil on the non-target organism Cyprinus carpio: implications for rice- fish cultivation. Ecotoxicol Environ Saf. 2012;77:45–51.
65. Chamorro-García R, Shoucri BM, Willner S, Käch H, Janesick A, Blumberg B. Effects of
perinatal exposure to dibutyltin chloride on fat and glucose metabolism in mice, and molecular mechanisms, in vitro. Environ Health Perspect. 2018;126(5):057006.
66. Mimoto MS, Nadal A, Sargis RM. Polluted pathways: mechanisms of metabolic disruption
by endocrine disrupting chemicals. Curr Environ Health Rep. 2017;4(2):208–22.
67. Yu J, Yang X, Yang X, Yang M, Wang P, Yang Y, et al. Nonylphenol aggravates non-alcoholic
fatty liver disease in high sucrose-high fat diet-treated rats. Sci Rep. 2018;8(1):1–9.
68. Guo L-W, Wu Q, Green B, Nolen G, Shi L, LoSurdo J, et al. Cytotoxicity and inhibitory
effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal
stem cells. Toxicol Appl Pharmacol. 2012;262(2):117–23.
69. Zhang W, Shen X-Y, Zhang W-W, Chen H, Xu W-P, Wei W. The effects of di 2-ethyl hexyl
phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms
in the molecular level. Toxicol Mech Methods. 2017;27(4):245–52.
70. Guan Y, Gao J, Zhang Y, Chen S, Yuan C, Wang Z. Effects of bisphenol A on lipid metabolism in rare minnow Gobiocypris rarus. Comp Biochem Physiol Part C Toxicol Pharmacol.
2016;179:144–9.
71. Lonare M, Kumar M, Raut S, More A, Doltade S, Badgujar P, et al. Evaluation of ameliorative effect of curcumin on imidacloprid-induced male reproductive toxicity in wistar rats.
Environ Toxicol. 2016;31(10):1250–63.
72. Khan S, Jan M, Kumar D, Telang A. Firpronil induced spermotoxicity is associated with oxidative stress, DNA damage and apoptosis in male rats. Pestic Biochem Physiol. 2015;124:8–14.
73. Lopez-Antia A, Ortiz-Santaliestra ME, Camarero PR, Mougeot F, Mateo R. Assessing the
risk of fipronil-treated seed ingestion and associated adverse effects in the red-legged partridge. Environ Sci Technol. 2015;49(22):13649–57.
74. Kocaman AY, Rencüzoğulları E, Topaktaş M. In vitro investigation of the genotoxic and
cytotoxic effects of thiacloprid in cultured human peripheral blood lymphocytes. Environ
Toxicol. 2014;29(6):631–41.
75. Chen J, Li L, Su J, Li B, Zhang X, Chen T. Proteomic analysis of G2/M arrest triggered by
natural borneol/curcumin in HepG2 cells, the importance of the reactive oxygen species-p53
pathway. J Agric Food Chem. 2015;63(28):6440–9.
76. Wang X-q, Li Y-g, Zhong S, Zhang H, Wang X-y, Qi P-p, et al. Oxidative injury is involved
in fipronil-induced G2/M phase arrest and apoptosis in Spodoptera frugiperda (Sf9) cell line.
Pestic Biochem Physiol. 2013;105(2):122–30.
77. Speakman JR, O’Rahilly S. Fat: an evolving issue. Cambridge: The Company of Biologists
Ltd; 2012.
78. Newbold RR, Padilla-Banks E, Jefferson WN, Heindel JJ. Effects of endocrine disruptors on
obesity. Int J Androl. 2008;31(2):201–8.
79. Toschke A, Koletzko B, Slikker W, Hermann M, von Kries R. Childhood obesity is associated
with maternal smoking in pregnancy. Eur J Pediatr. 2002;161(8):445–8.
80. Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, et al. Endocrine-disrupting
organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol.
2006;20(9):2141–55.
81. Newbold RR, Padilla-Banks E, Snyder RJ, Jefferson WN. Developmental exposure to estrogenic compounds and obesity. Birth Defects Res A Clin Mol Teratol. 2005;73(7):478–80.
17 Role of Pesticides as EDCs in Metabolic Disorders
62. McKinlay R, Plant JA, Bell JNB, Voulvoulis N. Calculating human exposure to endocrine
disrupting pesticides via agricultural and non-agricultural exposure routes. Sci Total Environ.
2008;398(1):1–12.
63. Weber D, Davies MJ, Grune T. Determination of protein carbonyls in plasma, cell extracts,
tissue homogenates, isolated proteins: focus on sample preparation and derivatization conditions. Redox Biol. 2015;5:367–80.
64. Clasen B, Loro VL, Cattaneo R, Moraes B, Lopes T, de Avila LA, et al. Effects of the commercial formulation containing fipronil on the non-target organism Cyprinus carpio: implications for rice- fish cultivation. Ecotoxicol Environ Saf. 2012;77:45–51.
65. Chamorro-García R, Shoucri BM, Willner S, Käch H, Janesick A, Blumberg B. Effects of
perinatal exposure to dibutyltin chloride on fat and glucose metabolism in mice, and molecular mechanisms, in vitro. Environ Health Perspect. 2018;126(5):057006.
66. Mimoto MS, Nadal A, Sargis RM. Polluted pathways: mechanisms of metabolic disruption
by endocrine disrupting chemicals. Curr Environ Health Rep. 2017;4(2):208–22.
67. Yu J, Yang X, Yang X, Yang M, Wang P, Yang Y, et al. Nonylphenol aggravates non-alcoholic
fatty liver disease in high sucrose-high fat diet-treated rats. Sci Rep. 2018;8(1):1–9.
68. Guo L-W, Wu Q, Green B, Nolen G, Shi L, LoSurdo J, et al. Cytotoxicity and inhibitory
effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal
stem cells. Toxicol Appl Pharmacol. 2012;262(2):117–23.
69. Zhang W, Shen X-Y, Zhang W-W, Chen H, Xu W-P, Wei W. The effects of di 2-ethyl hexyl
phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms
in the molecular level. Toxicol Mech Methods. 2017;27(4):245–52.
70. Guan Y, Gao J, Zhang Y, Chen S, Yuan C, Wang Z. Effects of bisphenol A on lipid metabolism in rare minnow Gobiocypris rarus. Comp Biochem Physiol Part C Toxicol Pharmacol.
2016;179:144–9.
71. Lonare M, Kumar M, Raut S, More A, Doltade S, Badgujar P, et al. Evaluation of ameliorative effect of curcumin on imidacloprid-induced male reproductive toxicity in wistar rats.
Environ Toxicol. 2016;31(10):1250–63.
72. Khan S, Jan M, Kumar D, Telang A. Firpronil induced spermotoxicity is associated with oxidative stress, DNA damage and apoptosis in male rats. Pestic Biochem Physiol. 2015;124:8–14.
73. Lopez-Antia A, Ortiz-Santaliestra ME, Camarero PR, Mougeot F, Mateo R. Assessing the
risk of fipronil-treated seed ingestion and associated adverse effects in the red-legged partridge. Environ Sci Technol. 2015;49(22):13649–57.
74. Kocaman AY, Rencüzoğulları E, Topaktaş M. In vitro investigation of the genotoxic and
cytotoxic effects of thiacloprid in cultured human peripheral blood lymphocytes. Environ
Toxicol. 2014;29(6):631–41.
75. Chen J, Li L, Su J, Li B, Zhang X, Chen T. Proteomic analysis of G2/M arrest triggered by
natural borneol/curcumin in HepG2 cells, the importance of the reactive oxygen species-p53
pathway. J Agric Food Chem. 2015;63(28):6440–9.
76. Wang X-q, Li Y-g, Zhong S, Zhang H, Wang X-y, Qi P-p, et al. Oxidative injury is involved
in fipronil-induced G2/M phase arrest and apoptosis in Spodoptera frugiperda (Sf9) cell line.
Pestic Biochem Physiol. 2013;105(2):122–30.
77. Speakman JR, O’Rahilly S. Fat: an evolving issue. Cambridge: The Company of Biologists
Ltd; 2012.
78. Newbold RR, Padilla-Banks E, Jefferson WN, Heindel JJ. Effects of endocrine disruptors on
obesity. Int J Androl. 2008;31(2):201–8.
79. Toschke A, Koletzko B, Slikker W, Hermann M, von Kries R. Childhood obesity is associated
with maternal smoking in pregnancy. Eur J Pediatr. 2002;161(8):445–8.
80. Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, et al. Endocrine-disrupting
organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol.
2006;20(9):2141–55.
81. Newbold RR, Padilla-Banks E, Snyder RJ, Jefferson WN. Developmental exposure to estrogenic compounds and obesity. Birth Defects Res A Clin Mol Teratol. 2005;73(7):478–80.
17 Role of Pesticides as EDCs in Metabolic Disorders