2.6 Conclusions
The current book chapter tries to review the global efforts by scientists regarding
their investigation on natural bioactive compounds from medicinal plants that will
serve as a novel chemotherapeutants and their general applications in various fields.
Alongside, this provides a prospect for further research in order to find novel
antimicrbial agents, their potentials, modes of action and synergistic effects for the
eventual formulation of herbal mixtures and their combination with synthetic
medicines. Such efforts will be more lucrative if their toxicological effects are
confirmed by necessary and careful studies. It will be more scientific to standardize
techniques of extraction, in vitro and in vivo antimicrobial efficacy testing so that
the search for new biologically active compounds could be more systematic and
results interpretation would be facilitated. The phytochemicals responsible for the
potential properties of the bioactive natural compounds are mainly phenolic acids,
alkaloids, flavonoids, saponins, glycosides, polysaccharides, tannins and stilbenes.
Notwithstaanding, the phytochemical composition in plant depend highly on several factors, including plant specie, genetic traits, plant organs used, and the
growing, drying, and storing condition. Moreover, new techniques must be
employed to get excellent plant products in high amounts and to determine their
potential applications more accurately in food industry, traditional medicine, cosmetics, drugs development and plant based pesticides and agrochemical industry.
References
Abdolshahi A, Naybandi-Atashi S, Heydari-Majd M, Salehi B, Kobarfard F, Ayatollahi SA,
Ata A, Tabanelli G, Sharifi-Rad M, Montanari C (2018) Antibacterial activity of some
lamiaceae species against Staphylococcus aureus in yoghurt-based drink (doogh). Cell Mol
Biol (Noisy Le Grand) 64
Abhishek T, Sharma N, Sharma V, Afroz AA (2013) review on conventional and
non-conventional methods to manage postharvest diseases of perishables. Researcher 5:6–19
Abid Ali Khan MM, Naqvi TS, Naqvi MS (2012) Identification of phytosaponins as novel
biodynamic agents: an updated overview. Asian J Exp Biol Sci 3:459–467
Abu-Darwish MS, Cabral C, Gonçalves MJ, Cavaleiro C, Cruz MT, Zulfiqar A, Khan IA,
Efferth T, Salgueiro L (2016) Chemical composition and biological activities of Artemisia
judaica essential oil from southern desert of jordan. J. Ethnopharmacol 191:161–168
Adedapo AA, Ofuegbe SO (2014) The evaluation of the hypoglycemic effect of soft drink leaf
extract of Phyllanthus amarus (euphorbiaceae) in rats. J Basic Clin Physiol Pharmacol 25:47–57
Adefegha SA, Oboh G, Adefegha OM, Boligon AA, Athayde ML (2014) Antihyperglycemic,
hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium
aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model. J Sci
Food Agric 94:2726–2737
Adeneye AA (2008) Methanol seed extract of Citrus paradisi macfad lowers blood glucose, lipids
and cardiovascular disease risk indices in normal wistar rats. Nig Q J Hosp Med 18:16–20
Ahad A, Mujeeb M, Ahsan H, Siddiqui WA (2014) Prophylactic effect of baicalein against renal
dysfunction in type 2 diabetic rats. Biochimie 106:101–110
78
T. Ahmadu and K. Ahmad
The current book chapter tries to review the global efforts by scientists regarding
their investigation on natural bioactive compounds from medicinal plants that will
serve as a novel chemotherapeutants and their general applications in various fields.
Alongside, this provides a prospect for further research in order to find novel
antimicrbial agents, their potentials, modes of action and synergistic effects for the
eventual formulation of herbal mixtures and their combination with synthetic
medicines. Such efforts will be more lucrative if their toxicological effects are
confirmed by necessary and careful studies. It will be more scientific to standardize
techniques of extraction, in vitro and in vivo antimicrobial efficacy testing so that
the search for new biologically active compounds could be more systematic and
results interpretation would be facilitated. The phytochemicals responsible for the
potential properties of the bioactive natural compounds are mainly phenolic acids,
alkaloids, flavonoids, saponins, glycosides, polysaccharides, tannins and stilbenes.
Notwithstaanding, the phytochemical composition in plant depend highly on several factors, including plant specie, genetic traits, plant organs used, and the
growing, drying, and storing condition. Moreover, new techniques must be
employed to get excellent plant products in high amounts and to determine their
potential applications more accurately in food industry, traditional medicine, cosmetics, drugs development and plant based pesticides and agrochemical industry.
References
Abdolshahi A, Naybandi-Atashi S, Heydari-Majd M, Salehi B, Kobarfard F, Ayatollahi SA,
Ata A, Tabanelli G, Sharifi-Rad M, Montanari C (2018) Antibacterial activity of some
lamiaceae species against Staphylococcus aureus in yoghurt-based drink (doogh). Cell Mol
Biol (Noisy Le Grand) 64
Abhishek T, Sharma N, Sharma V, Afroz AA (2013) review on conventional and
non-conventional methods to manage postharvest diseases of perishables. Researcher 5:6–19
Abid Ali Khan MM, Naqvi TS, Naqvi MS (2012) Identification of phytosaponins as novel
biodynamic agents: an updated overview. Asian J Exp Biol Sci 3:459–467
Abu-Darwish MS, Cabral C, Gonçalves MJ, Cavaleiro C, Cruz MT, Zulfiqar A, Khan IA,
Efferth T, Salgueiro L (2016) Chemical composition and biological activities of Artemisia
judaica essential oil from southern desert of jordan. J. Ethnopharmacol 191:161–168
Adedapo AA, Ofuegbe SO (2014) The evaluation of the hypoglycemic effect of soft drink leaf
extract of Phyllanthus amarus (euphorbiaceae) in rats. J Basic Clin Physiol Pharmacol 25:47–57
Adefegha SA, Oboh G, Adefegha OM, Boligon AA, Athayde ML (2014) Antihyperglycemic,
hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium
aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model. J Sci
Food Agric 94:2726–2737
Adeneye AA (2008) Methanol seed extract of Citrus paradisi macfad lowers blood glucose, lipids
and cardiovascular disease risk indices in normal wistar rats. Nig Q J Hosp Med 18:16–20
Ahad A, Mujeeb M, Ahsan H, Siddiqui WA (2014) Prophylactic effect of baicalein against renal
dysfunction in type 2 diabetic rats. Biochimie 106:101–110
78
T. Ahmadu and K. Ahmad