118
A. Bagaria and S. Ramakumar
Fig. 18 The figure shows the head-to-tail hydrogen bonding seen in the AF molecule. The side
chains not involved in interactions have been omitted for clarity
3.3.6 Discussions About Dipeptide III (AF)
The dipeptide III (AF) was characterized using various techniques apart from
X-ray crystallography. No tubular assembly was suggested by these techniques as
well. The crystal packing reveals the division of the dipeptide assembly into two
layers: hydrophilic and hydrophobic. The hydrophobic layers are formed by
the peptide side chain while the hydrophilic layers are formed by the peptide
main chain moieties and a water molecule.
The molecular packing depicted by AF is similar to its counterpart L -alanylL phenylalanyl (AF) with a co-crystallized organic solvent molecule (Görbitz 1999).
The peptide AF did not display any tubular structure as seen using different imaging
techniques (at the concentration at which Phe-Phe was investigated ~1 mg/ml).
4 Conclusion
Self-assembly has recently become a major thrust for material scientists. This process
of self-assembly ultimately would give us the potential to create artificial molecules,
whose architecture and function are not limited by the paradigms found in nature but
A. Bagaria and S. Ramakumar
Fig. 18 The figure shows the head-to-tail hydrogen bonding seen in the AF molecule. The side
chains not involved in interactions have been omitted for clarity
3.3.6 Discussions About Dipeptide III (AF)
The dipeptide III (AF) was characterized using various techniques apart from
X-ray crystallography. No tubular assembly was suggested by these techniques as
well. The crystal packing reveals the division of the dipeptide assembly into two
layers: hydrophilic and hydrophobic. The hydrophobic layers are formed by
the peptide side chain while the hydrophilic layers are formed by the peptide
main chain moieties and a water molecule.
The molecular packing depicted by AF is similar to its counterpart L -alanylL phenylalanyl (AF) with a co-crystallized organic solvent molecule (Görbitz 1999).
The peptide AF did not display any tubular structure as seen using different imaging
techniques (at the concentration at which Phe-Phe was investigated ~1 mg/ml).
4 Conclusion
Self-assembly has recently become a major thrust for material scientists. This process
of self-assembly ultimately would give us the potential to create artificial molecules,
whose architecture and function are not limited by the paradigms found in nature but