137
existed in a racemic form and the authors resolved to determine their absolute configurations using ECD spectra. Sample 5 produced four dimeric benzofurans (965,
966, 967, and 968) [268]. The same group reported the isolation of seven aromatics
(914, euparin (952), 954, 957, 969, 973, and 974) and a eudesmane (796) from
sample 6 (the same source as sample 5) [244]. It is quite interesting to observe that
compound 969 is dimeric, 973 trimeric, and 974 tetrameric.
3.17 Ligularia alticola Voroschilov
Four scientific reports were published on the chemical constituents of L. alticola
collected in Russia (Table 20). From sample 1 (roots), furanoeremophilan-15,6αolide (major constituent) (212), a lactone (218), a 15-oic acid (199), and lupeol
(828) were obtained [135]. The polar fraction of sample 2 (leaves) was investigated,
and the glucosides 81, 82, 83, 84, 85, 86, 87, 874, and 899 of eremophilanes and
other compounds were isolated [82]. A further study of sample 3 (leaves) resulted
Fig. 61 Other compounds
Chemical Constituents of Ligularia Species (Asteraceae) and Their Diversity…