101
3.10 Ligularia melanothyrsa Handel-Mazzetti
Samples 1 and 2 of L. melanothyrsa were collected, in turn, in Sichuan and Yunnan
Provinces, China (Table 13, Plates 11a and 11b). However, the phytochemical studies conducted revealed the constituents of these two samples to be quite different in
their composition. Sample 1 produced 11 eremophilanolides (344, 350, 353 (melanothyrsin A), 354 (melanothyrsin E), 359, 367, 368, 370 (melanothyrsin B), 371
(melanothyrsin C), 538 (eremofarfugin C), and 541 (melanothyrsin D)), three rearranged lactones (557, 559 (subspicatolide), and 560 (subspicatolide acetate)), three
bicyclic eremophilanes (9, 33, and 39), secobakkane A (151), three
Fig. 28 2-Oxoeremophil-1(10)-en-12,8-olides
Table 13 Samples 1 and 2 of L. melanothyrsa and their chemical constituents
No
Specimen
number
Collection
place
Elevation
(m)
Bicyclic
eremophilanes
10H Tricyclic
eremophilanes
Others Ref.
1. 2007-51
Jiulong (S) 3400
9, 33, 39, 131,
132, 136
344, 350, 353, 354,
359, 367, 368, 370,
371, 538, 541, 557,
559, 560
151,
629
[44]
2 2008-08
Shangri-La
(Y)
4000
4
198, 199, 200, 211,
212
−
[21]
Chemical Constituents of Ligularia Species (Asteraceae) and Their Diversity…