Figueroa RA, MacKay AA (2005) Sorption of oxytetracycline to iron oxides and iron oxide-rich
soils. Environ Sci Technol 39(17):6664–6671. https://doi.org/10.1021/es048044l
Figueroa RA, Leonard A, MacKay AA (2004) Modeling tetracycline antibiotic sorption to clays.
Environ Sci Technol 38(2):476–483. https://doi.org/10.1021/es0342087
Fischer S, Klüver N, Burkhardt-Medicke K et al (2013) Abcb4 acts as multixenobiotic transporter
and active barrier against chemical uptake in zebrafish (Danio rerio) embryos. BMC Biol
11(1):69. https://doi.org/10.1186/1741-7007-11-69
Fischer FC, Abele C, Droge STJ et al (2018) Cellular uptake kinetics of neutral and charged
chemicals in in vitro assays measured by fluorescence microscopy. Chem Res Toxicol 31
(8):646–657. https://doi.org/10.1021/acs.chemrestox.8b00019
Flewelling RF, Hubbell WL (1986a) Hydrophobic ion interactions with membranes. Thermodynamic analysis of tetraphenylphosphonium binding to vesicles. Biophys J 49(2):531–540.
https://doi.org/10.1016/S0006-3495(86)83663-3
Flewelling RF, Hubbell WL (1986b) The membrane dipole potential in a total membrane
potential model. Applications to hydrophobic ion interactions with membranes. Biophys J
49(2):541–552. https://doi.org/10.1016/S0006-3495(86)83664-5
Franco A, Ferranti A, Davidsen C, Trapp S (2010) An unexpected challenge: ionizable compounds
in the REACH chemical space. Int J Life Cycle Assess 15(4):321–325. https://doi.org/10.1007/
s11367-010-0165-6
Geisler A, Endo S, Goss K-U (2012) Partitioning of organic chemicals to storage lipids: elucidating
the dependence on fatty acid composition and temperature. Environ Sci Technol
46(17):9519–9524. https://doi.org/10.1021/es301921w
Goss KU, Bittermann K, Henneberger L, Linden L (2018) Equilibrium biopartitioning of organic
anions – a case study for humans and fish. Chemosphere 199:174–181. https://doi.org/10.1016/
j.chemosphere.2018.02.026
Gulde R, Anliker S, Kohler H-PE, Fenner K (2018) Ion trapping of amines in protozoa: a novel
removal mechanism for micropollutants in activated sludge. Environ Sci Technol 52(1):52–60.
https://doi.org/10.1021/acs.est.7b03556
Haftka JJH, Scherpenisse P, Jonker MTO, Hermens JLM (2013) Using polyacrylate-coated SPME
fibers to quantify sorption of polar and ionic organic contaminants to dissolved organic carbon.
Environ Sci Technol 47(9):4455–4462. https://doi.org/10.1021/es400236a
Haftka JJH, Hammer J, Hermens JLM (2015) Mechanisms of neutral and anionic surfactant
sorption to solid-phase microextraction fibers. Environ Sci Technol 49(18):11053–11061.
https://doi.org/10.1021/acs.est.5b02901
Hallén B, Sundwall A, Sandquist S (1985) Ion pair formation and gastrointestinal absorption of
emepronium. Acta Pharmacol Toxicol 57(4):271–278. https://doi.org/10.1111/j.1600-0773.
1985.tb00042.x
Hammer J, Haftka JJH, Scherpenisse P, Hermens JLM, de Voogt P (2018) Investigating hydrophilic
and electrostatic properties of surfactants using retention on two mixed-mode liquid chromatographic columns. J Chromatogr A 1571:185–192. https://doi.org/10.1016/j.chroma.2018.08.
024
Heikkinen AT, Mönkkönen J, Korjamo T (2009) Kinetics of cellular retention during Caco-2
permeation experiments: role of lysosomal sequestration and impact on permeability estimates.
J Pharmacol Exp Ther 328(3):882
Henneberger L, Goss KU, Endo S (2016a) Equilibrium sorption of structurally diverse organic ions
to bovine serum albumin. Environ Sci Technol 50(10):5119–5126. https://doi.org/10.1021/acs.
est.5b06176
Henneberger L, Goss KU, Endo S (2016b) Partitioning of organic ions to muscle protein: experimental data, modeling, and implications for in vivo distribution of organic ions. Environ Sci
Technol 50(13):7029–7036. https://doi.org/10.1021/acs.est.6b01417
Henneberger L, Mühlenbrink M, Fischer FC, Escher BI (2019) C18-coated solid-phase
microextraction fibers for the quantification of partitioning of organic acids to proteins, lipids,
and cells. Chem Res Toxicol 32(1):168–178. https://doi.org/10.1021/acs.chemrestox.8b00249
60
L. Henneberger and K.-U. Goss
soils. Environ Sci Technol 39(17):6664–6671. https://doi.org/10.1021/es048044l
Figueroa RA, Leonard A, MacKay AA (2004) Modeling tetracycline antibiotic sorption to clays.
Environ Sci Technol 38(2):476–483. https://doi.org/10.1021/es0342087
Fischer S, Klüver N, Burkhardt-Medicke K et al (2013) Abcb4 acts as multixenobiotic transporter
and active barrier against chemical uptake in zebrafish (Danio rerio) embryos. BMC Biol
11(1):69. https://doi.org/10.1186/1741-7007-11-69
Fischer FC, Abele C, Droge STJ et al (2018) Cellular uptake kinetics of neutral and charged
chemicals in in vitro assays measured by fluorescence microscopy. Chem Res Toxicol 31
(8):646–657. https://doi.org/10.1021/acs.chemrestox.8b00019
Flewelling RF, Hubbell WL (1986a) Hydrophobic ion interactions with membranes. Thermodynamic analysis of tetraphenylphosphonium binding to vesicles. Biophys J 49(2):531–540.
https://doi.org/10.1016/S0006-3495(86)83663-3
Flewelling RF, Hubbell WL (1986b) The membrane dipole potential in a total membrane
potential model. Applications to hydrophobic ion interactions with membranes. Biophys J
49(2):541–552. https://doi.org/10.1016/S0006-3495(86)83664-5
Franco A, Ferranti A, Davidsen C, Trapp S (2010) An unexpected challenge: ionizable compounds
in the REACH chemical space. Int J Life Cycle Assess 15(4):321–325. https://doi.org/10.1007/
s11367-010-0165-6
Geisler A, Endo S, Goss K-U (2012) Partitioning of organic chemicals to storage lipids: elucidating
the dependence on fatty acid composition and temperature. Environ Sci Technol
46(17):9519–9524. https://doi.org/10.1021/es301921w
Goss KU, Bittermann K, Henneberger L, Linden L (2018) Equilibrium biopartitioning of organic
anions – a case study for humans and fish. Chemosphere 199:174–181. https://doi.org/10.1016/
j.chemosphere.2018.02.026
Gulde R, Anliker S, Kohler H-PE, Fenner K (2018) Ion trapping of amines in protozoa: a novel
removal mechanism for micropollutants in activated sludge. Environ Sci Technol 52(1):52–60.
https://doi.org/10.1021/acs.est.7b03556
Haftka JJH, Scherpenisse P, Jonker MTO, Hermens JLM (2013) Using polyacrylate-coated SPME
fibers to quantify sorption of polar and ionic organic contaminants to dissolved organic carbon.
Environ Sci Technol 47(9):4455–4462. https://doi.org/10.1021/es400236a
Haftka JJH, Hammer J, Hermens JLM (2015) Mechanisms of neutral and anionic surfactant
sorption to solid-phase microextraction fibers. Environ Sci Technol 49(18):11053–11061.
https://doi.org/10.1021/acs.est.5b02901
Hallén B, Sundwall A, Sandquist S (1985) Ion pair formation and gastrointestinal absorption of
emepronium. Acta Pharmacol Toxicol 57(4):271–278. https://doi.org/10.1111/j.1600-0773.
1985.tb00042.x
Hammer J, Haftka JJH, Scherpenisse P, Hermens JLM, de Voogt P (2018) Investigating hydrophilic
and electrostatic properties of surfactants using retention on two mixed-mode liquid chromatographic columns. J Chromatogr A 1571:185–192. https://doi.org/10.1016/j.chroma.2018.08.
024
Heikkinen AT, Mönkkönen J, Korjamo T (2009) Kinetics of cellular retention during Caco-2
permeation experiments: role of lysosomal sequestration and impact on permeability estimates.
J Pharmacol Exp Ther 328(3):882
Henneberger L, Goss KU, Endo S (2016a) Equilibrium sorption of structurally diverse organic ions
to bovine serum albumin. Environ Sci Technol 50(10):5119–5126. https://doi.org/10.1021/acs.
est.5b06176
Henneberger L, Goss KU, Endo S (2016b) Partitioning of organic ions to muscle protein: experimental data, modeling, and implications for in vivo distribution of organic ions. Environ Sci
Technol 50(13):7029–7036. https://doi.org/10.1021/acs.est.6b01417
Henneberger L, Mühlenbrink M, Fischer FC, Escher BI (2019) C18-coated solid-phase
microextraction fibers for the quantification of partitioning of organic acids to proteins, lipids,
and cells. Chem Res Toxicol 32(1):168–178. https://doi.org/10.1021/acs.chemrestox.8b00249
60
L. Henneberger and K.-U. Goss