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42. Yu Z, Pan Y, Wang Z, Wang J, Lin Q (2012) Genetically encoded cyclopropene directs rapid,
photoclick-chemistry-mediated protein labeling in mammalian cells. Angew Chemie Int Ed
51:10600–10604
43. An P, Wu H-Y, Lewandowski TM, Lin Q (2018) Hydrophilic azaspiroalkenes as robust
bioorthogonal reporters. Chem Commun 54:14005–14008
44. Zhang L, Zhang X, Yao Z, Jiang S, Deng J, Li B, Yu Z (2018) Discovery of fluorogenic
diarylsydnone-alkene photoligation: conversion of ortho-dual-twisted diarylsydnones into
planar pyrazolines. J Am Chem Soc 140:7390–7394
45. Zhang X, Wu X, Jiang S, Gao J, Yao Z, Deng J, Zhang L, Yu Z (2019) Photo-accelerated
“Click” reaction between Diarylsydnones and ring-strained alkynes for bioorthogonal ligation.
Chem Commun 55:7187–7190
46. Kamber DN, Nazarova LA, Liang Y, Lopez SA, Patterson DM, Shih H-W, Houk KN, Prescher
JA (2013) Isomeric cyclopropenes exhibit unique bioorthogonal reactivities. J Am Chem Soc
135:13680–13683
47. Wang Y, Hu WJ, Song W, Lim RKV, Lin Q (2008) Discovery of long-wavelength photoactivatable diaryltetrazoles for bioorthogonal 1,3-dipolar cycloaddition reactions. Org Lett
10:3725–3728
48. An P, Yu Z, Lin Q (2013) Design and synthesis of laser-activatable tetrazoles for a fast and
fluorogenic red-emitting 1,3-dipolar cycloaddition reaction. Org Lett 15:5496–5499
49. An P, Yu Z, Lin Q (2013) Design of Oligothiophene-based tetrazoles for laser-triggered
photoclick chemistry in living cells. Chem Commun 49:9920
50. An P, Lewandowski T, Erbay TG, Liu P, Lin Q (2018) A sterically shielded, stabilized nitrile
imine for rapid bioorthogonal protein labeling in live cells. J Am Chem Soc 140:4860–4868
51. An P, Lin Q (2018) Sterically shielded tetrazoles for a fluorogenic photoclick reaction: tuning
cycloaddition rate and product fluorescence. Org Biomol Chem 16:5241–5244
52. Zhang Y, Liu W, Zhao Z (2013) Nucleophilic trapping Nitrilimine generated by photolysis of
diaryltetrazole in aqueous phase. Molecules 19:306–315
53. Siti W, Khan AK, de Hoog H-PM, Liedberg B, Nallani M (2015) Photo-induced conjugation
of Tetrazoles to modified and native proteins. Org Biomol Chem 13:3202–3206
54. Li Z, Qian L, Li L, Bernhammer JC, Huynh HV, Lee J-S, Yao SQ (2015) Tetrazole photoclick
chemistry: reinvestigating its suitability as a bioorthogonal reaction and potential applications.
Angew Chem Int Ed Engl 55:2002–2006
55. Zhao S, Dai J, Hu M, Liu C, Meng R, Liu X, Wang C, Luo T (2016) Photo-induced coupling reactions of Tetrazoles with carboxylic acids in aqueous solution: application in protein
labelling. Chem Commun 52:4702–4705
56. Herner A, Marjanovic J, Lewandowski TM, Marin V, Patterson M, Miesbauer L, Ready D,
Williams J, Vasudevan A, Lin Q (2016) 2-Aryl-5-carboxytetrazole as a new photoaffinity
label for drug target identification. J Am Chem Soc 138:14609–14615
57. Tian Y, Jacinto MP, Zeng Y, Yu Z, Qu J, Liu WR, Lin Q (2017) Genetically encoded 2-Aryl-5carboxytetrazoles for site-selective protein photo-cross-linking. J Am Chem Soc 139:6078–
6081
58. Tian Y, Lin Q (2018) Genetic encoding of 2-Aryl-5-carboxytetrazole-based protein photocross-linkers. Chem Commun 54:4449–4452
59. Li Z, Cheng K, Lee J-S, Yao SQ, Ding K (2017) Tetrazole-based probes for integrated
phenotypic screening, affinity-based proteome profiling and sensitive detection of a cancer
biomarker. Angew Chemie Int Ed 56:15044–15048
60. Lau YH, de Andrade P, Wu Y, Spring DR (2015) Peptide stapling techniques based on different
macrocyclisation chemistries. Chem Soc Rev 44:91–102
61. Madden MM, Rivera Vera CI, Song W, Lin Q (2009) Facile synthesis of stapled, structurally reinforced peptide helices via a photoinduced intramolecular 1,3-dipolar cycloaddition
reaction. Chem Commun 2009:5588–5590
62. Madden MM, Muppidi A, Li Z, Li X, Chen J, Lin Q (2011) Synthesis of cell-permeable stapled
peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition.
Bioorg Med Chem Lett 21:1472–1475