17. Luo Y et al (2014) A review on the occurrence of micropollutants in the aquatic environment
and their fate and removal during wastewater treatment. Sci Total Environ 473–474:619–641
18. Salgado R, Marques R, Noronha JP, Mexia JT, Carvalho G, Oehmen A, Reis MA (2011)
Assessing the diurnal variability of pharmaceutical and personal care products in a full-scale
activated sludge plant. Environ Pollut 159(10):2359–2367
19. Farré M et al (2008) First interlaboratory exercise on non-steroidal anti-inflammatory drugs
analysis in environmental samples. Talanta 76(3):580–590
20. Petrovic M et al (2009) Fate and removal of pharmaceuticals and illicit drugs in conventional
and membrane bioreactor wastewater treatment plants and by riverbank filtration. Philos Trans
R Soc A 367(1904):3979–4003
21. Nishi I, Kawakami T, Onodera S (2015) Monitoring the concentrations of nonsteroidal antiinflammatory drugs and cyclooxygenase-inhibiting activities in the surface waters of the Tone
Canal and Edo River basin. J Environ Sci Health Part A Toxic Hazard Subst Environ Eng 50
(11):1108–1115
22. Lolić A, Paíga P, Santos LHMLM, Ramos S, Correia M, Delerue-Matos C (2015) Assessment
of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of
Portugal: Occurrence and environmental risk. Sci Total Environ 508:240–250
23. Pomiès M, Choubert JM, Wisniewski C, Coquery M (2013) Modelling of micropollutant
removal in biological wastewater treatments: a review. Sci Total Environ 443:733–748
24. Schröder HF, Tambosi JL, Sena RF, Moreira RFPM, José HJ, Pinnekamp J (2012) The removal
and degradation of pharmaceutical compounds during membrane bioreactor treatment. Water
Sci Technol 65(5):833–839
25. Kruglova A et al (2016) Comparative study of emerging micropollutants removal by aerobic
activated sludge of large laboratory-scale membrane bioreactors and sequencing batch reactors
under low-temperature conditions. Bioresour Technol 214:81–88
26. Feng L, van Hullebusch ED, Rodrigo MA, Esposito G, Oturan MA (2013) Removal of residual
anti-inflammatory and analgesic pharmaceuticals from aqueous systems by electrochemical
advanced oxidation processes. A review. Chem Eng J 228:944–964
27. Vieno N, Tuhkanen T, Kronberg L (2007) Elimination of pharmaceuticals in sewage treatment
plants in Finland. Water Res 41(5):1001–1012
28. Cuerda-Correa EM, Domínguez-Vargas JR, Olivares-Marín FJ, de Heredia JB (2010) On the
use of carbon blacks as potential low-cost adsorbents for the removal of non-steroidal antiinflammatory drugs from river water. J Hazard Mater 177(1–3):1046–1053
29. Gundogdu-Hizliates C, Alyuruk H, Gocmenturk M, Ergun Y, Cavas L (2014) Synthesis of new
ibuprofen derivatives with their in silico and in vitro cyclooxygenase-2 inhibitions. Bioorg
Chem 52:8–15
30. Narsinghani T, Sharma R (2014) Lead optimization on conventional non-steroidal anti-inflammatory drugs: an approach to reduce gastrointestinal toxicity. Chem Biol Drug Des 84(1):1–23
31. Behera SK, Kim HW, Oh JE, Park HS (2011) Occurrence and removal of antibiotics, hormones
and several other pharmaceuticals in wastewater treatment plants of the largest industrial city of
Korea. Sci Total Environ 409(20):4351–4360
32. Lindqvist N, Tuhkanen T, Kronberg L (2005) Occurrence of acidic pharmaceuticals in raw and
treated sewages and in receiving waters. Water Res 39(11):2219–2228
33. Larsson N, Petersson E, Rylander M, Jönsson JA (2009) Continuous flow hollow fiber liquidphase microextraction and monitoring of NSAID pharmaceuticals in a sewage treatment plant
effluent. Anal Methods 1(1):59–67
34. Koutsouba V, Heberer T, Fuhrmann B, Schmidt-Baumler K, Tsipi D, Hiskia A (2003) Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass
spectrometry. Chemosphere 51(2):69–75
35. Mlunguza NY, Ncube S, Nokwethemba Mahlambi P, Chimuka L, Madikizela LM (2019)
Adsorbents and removal strategies of non-steroidal anti-inflammatory drugs from contaminated
water bodies. J Environ Chem Eng 7(3):103142
36. Qurie M et al (2014) Stability and removal of naproxen and its metabolite by advanced
membrane wastewater treatment plant and micelle-clay complex. Clean (Weinh) 42(5):594–600
Use of Membrane for Removal of Nonsteroidal Anti-inflammatory Drugs
275
and their fate and removal during wastewater treatment. Sci Total Environ 473–474:619–641
18. Salgado R, Marques R, Noronha JP, Mexia JT, Carvalho G, Oehmen A, Reis MA (2011)
Assessing the diurnal variability of pharmaceutical and personal care products in a full-scale
activated sludge plant. Environ Pollut 159(10):2359–2367
19. Farré M et al (2008) First interlaboratory exercise on non-steroidal anti-inflammatory drugs
analysis in environmental samples. Talanta 76(3):580–590
20. Petrovic M et al (2009) Fate and removal of pharmaceuticals and illicit drugs in conventional
and membrane bioreactor wastewater treatment plants and by riverbank filtration. Philos Trans
R Soc A 367(1904):3979–4003
21. Nishi I, Kawakami T, Onodera S (2015) Monitoring the concentrations of nonsteroidal antiinflammatory drugs and cyclooxygenase-inhibiting activities in the surface waters of the Tone
Canal and Edo River basin. J Environ Sci Health Part A Toxic Hazard Subst Environ Eng 50
(11):1108–1115
22. Lolić A, Paíga P, Santos LHMLM, Ramos S, Correia M, Delerue-Matos C (2015) Assessment
of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of
Portugal: Occurrence and environmental risk. Sci Total Environ 508:240–250
23. Pomiès M, Choubert JM, Wisniewski C, Coquery M (2013) Modelling of micropollutant
removal in biological wastewater treatments: a review. Sci Total Environ 443:733–748
24. Schröder HF, Tambosi JL, Sena RF, Moreira RFPM, José HJ, Pinnekamp J (2012) The removal
and degradation of pharmaceutical compounds during membrane bioreactor treatment. Water
Sci Technol 65(5):833–839
25. Kruglova A et al (2016) Comparative study of emerging micropollutants removal by aerobic
activated sludge of large laboratory-scale membrane bioreactors and sequencing batch reactors
under low-temperature conditions. Bioresour Technol 214:81–88
26. Feng L, van Hullebusch ED, Rodrigo MA, Esposito G, Oturan MA (2013) Removal of residual
anti-inflammatory and analgesic pharmaceuticals from aqueous systems by electrochemical
advanced oxidation processes. A review. Chem Eng J 228:944–964
27. Vieno N, Tuhkanen T, Kronberg L (2007) Elimination of pharmaceuticals in sewage treatment
plants in Finland. Water Res 41(5):1001–1012
28. Cuerda-Correa EM, Domínguez-Vargas JR, Olivares-Marín FJ, de Heredia JB (2010) On the
use of carbon blacks as potential low-cost adsorbents for the removal of non-steroidal antiinflammatory drugs from river water. J Hazard Mater 177(1–3):1046–1053
29. Gundogdu-Hizliates C, Alyuruk H, Gocmenturk M, Ergun Y, Cavas L (2014) Synthesis of new
ibuprofen derivatives with their in silico and in vitro cyclooxygenase-2 inhibitions. Bioorg
Chem 52:8–15
30. Narsinghani T, Sharma R (2014) Lead optimization on conventional non-steroidal anti-inflammatory drugs: an approach to reduce gastrointestinal toxicity. Chem Biol Drug Des 84(1):1–23
31. Behera SK, Kim HW, Oh JE, Park HS (2011) Occurrence and removal of antibiotics, hormones
and several other pharmaceuticals in wastewater treatment plants of the largest industrial city of
Korea. Sci Total Environ 409(20):4351–4360
32. Lindqvist N, Tuhkanen T, Kronberg L (2005) Occurrence of acidic pharmaceuticals in raw and
treated sewages and in receiving waters. Water Res 39(11):2219–2228
33. Larsson N, Petersson E, Rylander M, Jönsson JA (2009) Continuous flow hollow fiber liquidphase microextraction and monitoring of NSAID pharmaceuticals in a sewage treatment plant
effluent. Anal Methods 1(1):59–67
34. Koutsouba V, Heberer T, Fuhrmann B, Schmidt-Baumler K, Tsipi D, Hiskia A (2003) Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass
spectrometry. Chemosphere 51(2):69–75
35. Mlunguza NY, Ncube S, Nokwethemba Mahlambi P, Chimuka L, Madikizela LM (2019)
Adsorbents and removal strategies of non-steroidal anti-inflammatory drugs from contaminated
water bodies. J Environ Chem Eng 7(3):103142
36. Qurie M et al (2014) Stability and removal of naproxen and its metabolite by advanced
membrane wastewater treatment plant and micelle-clay complex. Clean (Weinh) 42(5):594–600
Use of Membrane for Removal of Nonsteroidal Anti-inflammatory Drugs
275