54
Griffiths H, Mistry P, Herbert K, Lunec J (1998) Molecular and cellular effects of ultraviolet light-induced genotoxicity. Crit Rev Clin Lab Sci 35(3):189–237. https://doi.
org/10.1080/10408369891234192
Iannacone M, Green A (2014) Towards skin cancer prevention and early detection: evolution
of skin cancer awareness campaigns in Australia. Melanoma Manag 1(1):75–84. https://doi.
org/10.2217/mmt.14.6
Ikehata H, Ono T (2011) The mechanisms of UV mutagenesis. J Radiat Res 52(2):115–125.
https://doi.org/10.1269/jrr.10175
Ismail F, Ikram M, Purdie K, Harwood C, Leigh I, Storey A (2011) Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and
malignant keratinocyte skin lesions. PLoS One 6(7):e21271. https://doi.org/10.1371/journal.
pone.0021271
Jackson S, Bartek J (2009) The DNA-damage response in human biology and disease. Nature
461(7267):1071–1078. https://doi.org/10.1038/nature08467
Kim I, He Y (2014) Ultraviolet radiation-induced non-melanoma skin cancer: regulation of
DNA damage repair and inflammation. Genes Dis 1(2):188–198. https://doi.org/10.1016/j.
gendis.2014.08.005
Kirsch D (2015) Biomarkers for predicting radiation response. Semin Radiat Oncol 25(4):225–
226. https://doi.org/10.1016/j.semradonc.2015.05.011
Mitchell D (2018) Canada moves to ban indoor tanning in kids under 18. Emax Health, White
Plains
Moan J, Dahlback A (1992) The relationship between skin cancers, solar radiation and ozone
depletion. Br J Cancer 65(6):916–921. https://doi.org/10.1038/bjc.1992.192
Narayanan D, Saladi R, Fox J (2010) Review: ultraviolet radiation and skin cancer. Int J Dermatol
49(9):978–986. https://doi.org/10.1111/j.1365-4632.2010.04474.x
Nikolaishvilli-Feinberg N, Cohen S, Midkiff B, Zhou Y, Olorvida M, Ibrahim J et al
(2013) Development of DNA damage response signaling biomarkers using automated, quantitative image analysis. J Histochem Cytochem 62(3):185–196. https://doi.
org/10.1369/0022155413516469
Norval M, Lucas R, Cullen A, de Gruijl F, Longstreth J, Takizawa Y, van der Leun J (2011) The
human health effects of ozone depletion and interactions with climate change. Photochem
Photobiol Sci 10(2):199. https://doi.org/10.1039/c0pp90044c
Ohnaka T (1993) Health effects of ultraviolet radiation. Ann Physiol Anthropol 12(1):1–10. https://
doi.org/10.2114/ahs1983.12.1
Pray L (2008) Discovery of DNA structure and function: Watson and Crick. Nat Educ 1:1
Roy S (2017) Impact of UV radiation on genome stability and human health. In: Ultraviolet light
in human health, diseases and environment. Springer, Cham, pp 207–219
Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M (2011) Double-strand break repairindependent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell
145(4):529–542. https://doi.org/10.1016/j.cell.2011.03.041
Speroni J, Federico M, Mansilla S, Soria G, Gottifredi V (2012) Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA. Proc Natl Acad Sci
109(19):7344–7349. https://doi.org/10.1073/pnas.1116345109
Spivak G (2015) Nucleotide excision repair in humans. DNA Repair 36:13–18. https://doi.
org/10.1016/j.dnarep.2015.09.003
Stark J (2009) Tanning salons are fading fast. THE AGE. theage.com.au
UNEP (1998) Ozone layer-climate change interactions. Influence on UV levels and UV related
effects. Environmental effects of ozone depletion: 1998 assessment
UNEP/WG 160 (1987) Fifth meeting of the Working Group for Scientific and Technical
Co-operation for MED POL
Vallerga M, Mansilla S, Federico M, Bertolin A, Gottifredi V (2015) Rad51 recombinase prevents
Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent
DNA after UV radiation. Proc Natl Acad Sci 112(48):E6624–E6633. https://doi.org/10.1073/
pnas.1508543112
M. B. Federico
Griffiths H, Mistry P, Herbert K, Lunec J (1998) Molecular and cellular effects of ultraviolet light-induced genotoxicity. Crit Rev Clin Lab Sci 35(3):189–237. https://doi.
org/10.1080/10408369891234192
Iannacone M, Green A (2014) Towards skin cancer prevention and early detection: evolution
of skin cancer awareness campaigns in Australia. Melanoma Manag 1(1):75–84. https://doi.
org/10.2217/mmt.14.6
Ikehata H, Ono T (2011) The mechanisms of UV mutagenesis. J Radiat Res 52(2):115–125.
https://doi.org/10.1269/jrr.10175
Ismail F, Ikram M, Purdie K, Harwood C, Leigh I, Storey A (2011) Cutaneous squamous cell carcinoma (SCC) and the DNA damage response: pATM expression patterns in pre-malignant and
malignant keratinocyte skin lesions. PLoS One 6(7):e21271. https://doi.org/10.1371/journal.
pone.0021271
Jackson S, Bartek J (2009) The DNA-damage response in human biology and disease. Nature
461(7267):1071–1078. https://doi.org/10.1038/nature08467
Kim I, He Y (2014) Ultraviolet radiation-induced non-melanoma skin cancer: regulation of
DNA damage repair and inflammation. Genes Dis 1(2):188–198. https://doi.org/10.1016/j.
gendis.2014.08.005
Kirsch D (2015) Biomarkers for predicting radiation response. Semin Radiat Oncol 25(4):225–
226. https://doi.org/10.1016/j.semradonc.2015.05.011
Mitchell D (2018) Canada moves to ban indoor tanning in kids under 18. Emax Health, White
Plains
Moan J, Dahlback A (1992) The relationship between skin cancers, solar radiation and ozone
depletion. Br J Cancer 65(6):916–921. https://doi.org/10.1038/bjc.1992.192
Narayanan D, Saladi R, Fox J (2010) Review: ultraviolet radiation and skin cancer. Int J Dermatol
49(9):978–986. https://doi.org/10.1111/j.1365-4632.2010.04474.x
Nikolaishvilli-Feinberg N, Cohen S, Midkiff B, Zhou Y, Olorvida M, Ibrahim J et al
(2013) Development of DNA damage response signaling biomarkers using automated, quantitative image analysis. J Histochem Cytochem 62(3):185–196. https://doi.
org/10.1369/0022155413516469
Norval M, Lucas R, Cullen A, de Gruijl F, Longstreth J, Takizawa Y, van der Leun J (2011) The
human health effects of ozone depletion and interactions with climate change. Photochem
Photobiol Sci 10(2):199. https://doi.org/10.1039/c0pp90044c
Ohnaka T (1993) Health effects of ultraviolet radiation. Ann Physiol Anthropol 12(1):1–10. https://
doi.org/10.2114/ahs1983.12.1
Pray L (2008) Discovery of DNA structure and function: Watson and Crick. Nat Educ 1:1
Roy S (2017) Impact of UV radiation on genome stability and human health. In: Ultraviolet light
in human health, diseases and environment. Springer, Cham, pp 207–219
Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M (2011) Double-strand break repairindependent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell
145(4):529–542. https://doi.org/10.1016/j.cell.2011.03.041
Speroni J, Federico M, Mansilla S, Soria G, Gottifredi V (2012) Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA. Proc Natl Acad Sci
109(19):7344–7349. https://doi.org/10.1073/pnas.1116345109
Spivak G (2015) Nucleotide excision repair in humans. DNA Repair 36:13–18. https://doi.
org/10.1016/j.dnarep.2015.09.003
Stark J (2009) Tanning salons are fading fast. THE AGE. theage.com.au
UNEP (1998) Ozone layer-climate change interactions. Influence on UV levels and UV related
effects. Environmental effects of ozone depletion: 1998 assessment
UNEP/WG 160 (1987) Fifth meeting of the Working Group for Scientific and Technical
Co-operation for MED POL
Vallerga M, Mansilla S, Federico M, Bertolin A, Gottifredi V (2015) Rad51 recombinase prevents
Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent
DNA after UV radiation. Proc Natl Acad Sci 112(48):E6624–E6633. https://doi.org/10.1073/
pnas.1508543112
M. B. Federico