Supramolecular Assembly Constructed
from Multi-charged Cyclodextrin-Induced
Aggregation
21
Pei-Yu Li, Yong Chen, and Yu Liu
Contents
21.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573
21.2 Supramolecular Assembly Constructed from Polyanionic Cyclodextrin-Induced
Aggregation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574
21.3 Supramolecular Assembly Constructed from Polycationic Cyclodextrin-Induced
Aggregation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581
21.4 Conclusions and Outlook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585
21.1 Introduction
Cyclodextrins are a family of cyclic oligosaccharides containing 6-8 D-glucose
units linked by α-1,4-glucose bonds, referred to as α-, β-, and γ-cyclodextrin,
respectively. As generated from the enzymatic degradation, cyclodextrins are
water-soluble, nontoxic, and commercially available at a low cost. More importantly, as the second generation of supramolecular macrocycles, cyclodextrins
could bind various neutral or negatively charged shape-compatible guest molecules by the hydrophobic cavity. This fascinating property made cyclodextrin a
good candidate in molecular recognition, sensing, drug carriers, biomimetic catalysts, and so on [1–3].
P.-Y. Li · Y. Chen · Y. Liu (*)
College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University,
Tianjin, China
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin),
Tianjin, China
e-mail: 747279263@qq.com; chenyong@nankai.edu.cn; yuliu@nankai.edu.cn
© Springer Nature Singapore Pte Ltd. 2020
Y. Liu et al. (eds.), Handbook of Macrocyclic Supramolecular Assembly,
https://doi.org/10.1007/978-981-15-2686-2_23
573
from Multi-charged Cyclodextrin-Induced
Aggregation
21
Pei-Yu Li, Yong Chen, and Yu Liu
Contents
21.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573
21.2 Supramolecular Assembly Constructed from Polyanionic Cyclodextrin-Induced
Aggregation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574
21.3 Supramolecular Assembly Constructed from Polycationic Cyclodextrin-Induced
Aggregation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581
21.4 Conclusions and Outlook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585
21.1 Introduction
Cyclodextrins are a family of cyclic oligosaccharides containing 6-8 D-glucose
units linked by α-1,4-glucose bonds, referred to as α-, β-, and γ-cyclodextrin,
respectively. As generated from the enzymatic degradation, cyclodextrins are
water-soluble, nontoxic, and commercially available at a low cost. More importantly, as the second generation of supramolecular macrocycles, cyclodextrins
could bind various neutral or negatively charged shape-compatible guest molecules by the hydrophobic cavity. This fascinating property made cyclodextrin a
good candidate in molecular recognition, sensing, drug carriers, biomimetic catalysts, and so on [1–3].
P.-Y. Li · Y. Chen · Y. Liu (*)
College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University,
Tianjin, China
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin),
Tianjin, China
e-mail: 747279263@qq.com; chenyong@nankai.edu.cn; yuliu@nankai.edu.cn
© Springer Nature Singapore Pte Ltd. 2020
Y. Liu et al. (eds.), Handbook of Macrocyclic Supramolecular Assembly,
https://doi.org/10.1007/978-981-15-2686-2_23
573