228
spectrometer, with DLS, at a detection angle of 90° and at
25 °C.
4. Analyze the measurements by the CONTIN method.
The physicochemical properties of DPPC liposomes with incorporated thermoresponsive amphiphilic block copolymer PNIPAM-bPLA 1 in different molar ratios after preparation, as well as after
heating, are presented in Fig. 3.
3.9 Physicochemical
Properties of the
Thermoresponsive
Chimeric Liposomes
0.0
200.0
400.0
600.0
800.0
1000.0
1200.0
DPPC
9:0.02
9:0.05
9:0.1
D
h (nm)
Molar Ratio
Size
0.000
0.200
0.400
0.600
0.800
1.000
DPPC
9:0.02
9:0.05
9:0.1
PDI
Molar Ratio
Thermoresponsive Liposomes
Agglomeration
T
Polydispersity
A
B
C
Fig. 3 Physicochemical properties, regarding (A) size and (B) polydispersity, of DPPC:PNIPAM-b-PLA 1 chimeric
liposomes after preparation (blue bars) and after heating at 45 °C (red bars) and (C) proposed mechanism of
the thermoresponsive behavior of chimeric liposomes
Nikolaos Naziris et al.
spectrometer, with DLS, at a detection angle of 90° and at
25 °C.
4. Analyze the measurements by the CONTIN method.
The physicochemical properties of DPPC liposomes with incorporated thermoresponsive amphiphilic block copolymer PNIPAM-bPLA 1 in different molar ratios after preparation, as well as after
heating, are presented in Fig. 3.
3.9 Physicochemical
Properties of the
Thermoresponsive
Chimeric Liposomes
0.0
200.0
400.0
600.0
800.0
1000.0
1200.0
DPPC
9:0.02
9:0.05
9:0.1
D
h (nm)
Molar Ratio
Size
0.000
0.200
0.400
0.600
0.800
1.000
DPPC
9:0.02
9:0.05
9:0.1
PDI
Molar Ratio
Thermoresponsive Liposomes
Agglomeration
T
Polydispersity
A
B
C
Fig. 3 Physicochemical properties, regarding (A) size and (B) polydispersity, of DPPC:PNIPAM-b-PLA 1 chimeric
liposomes after preparation (blue bars) and after heating at 45 °C (red bars) and (C) proposed mechanism of
the thermoresponsive behavior of chimeric liposomes
Nikolaos Naziris et al.