11
hsmc.gr/wp-content/uploads/2019/02/
issue_4_2018.pdf
26. Liossi A, Ntountaniotis D, Kellici T,
Chatziathanasiadou M, Megariotis G, Mania
M, Becker-Baldus J, Kriechbaum M, Krajnc
A, Christodoulou E, Glaubitz C, Rappolt
M, Amenitsch H, Mali G, Theodorou D,
Valsami G, Pitsikalis M, Iatrou H, Tzakos A,
Mavromoustakos T (2017) Exploring the
interactions of irbesartan and irbesartan–2hydroxypropyl- β-cyclodextrin complex with
model membranes. Biochim Biophys Acta
1859:1089–1098
27. Ntountaniotis D, Andreadelis I, Kellici TF,
Karageorgos V, Leonis G, Christodoulou
E, Kiriakidi S, Becker-Baldus J, Stylos EK,
Chatziathanasiadou MV, Chatzigiannis CM,
Damalas DE, Aksoydan B, Javornik U, Valsami
G, Glaubitz C, Durdagi S, Thomaidis NS,
Kolocouris A, Plavec J, Tzakos AG, Liapakis
G, Mavromoustakos T (2019) Host-guest
interactions between candesartan and its prodrug candesartan cilexetil in complex with
2-hydroxypropyl-β-cyclodextrin: on the biological potency for Angiotensin II. Mol Pharm
16(3):1255–1271
28. Kellici TF, Ntountaniotis D, Leonis G,
Chatziathanasiadou M, Chatzikonstantinou
AV, Becker-Baldus J, Glaubitz C, Tzakos AG,
Viras K, Chatzigeorgiou P, Tzimas S, Kefala E,
Valsami G, Archontaki H, Papadopoulos MG,
Mavromoustakos T (2015) Investigation of the
interactions of silibinin with 2- hydroxypropylβ-cyclodextrin through biophysical techniques
and computational methods. Mol Pharm
12(3):954–965
29. Kellici TF, Chatziathanasiadou MV, Diamantis
D, Chatzikonstantinou AV, Andreadelis I,
Christodoulou E, Valsami G, Mavromoustakos
T, Tzakos AG (2016) Mapping the interactions and bioactivity of quercetin–
(2-hydroxypropyl)-cyclodextrin complex. Int J
Pharm 511(1):303–311
30. Diamantis DA, Ramesova S, Chatzigiannis
C, Degano I, Gerogianni P, Karadima K,
Perikleous S, Rekkas D, Gerothanassis I, Galaris
D, Mavromoustakos T, Valsami G, Sokolova R,
Tzakos A (2018) Exploring the oxidation and
iron binding profile of a cyclodextrin encapsulated quercetin complex unveiled a controlled
complex dissociation through a chemical stimulus. BBA-General Subjects 1862:1913–1924
31. Papakyriakopoulou P, Manta K, Spaneas D,
Christodoulou E, Colombo G, Rekkas D,
Dallas P, Valsami G (2019) Ex vivo transport
study on quercetin-cyclodextrin inclusion complexes as candidates for nose-to-brain delivery.
AAPS PharmSci 360:3–6
32. Christodoulou
E,
Kechagia
IA,
Kostomitsopoulos N, Balafas E, Archontaki
E, Dokoumetzidis A, Valsami G (2015)
Pharmacokinetics of silibinin after peros
and intravenous administration to mice, as a
HP-β-CD lyophilized product. Int J Pharm
493:366–373
33. Tsaroucha A, Valsami G, Kostomitsopoulos
N, Lambropoulou M, Anagnostopoulos
C, Christodoulou E, Falidas E, Betsou A,
Kakazanis Z, Pitiakoudis M, Simopoulos C
(2018) Silibinin effect on Fas/FasL, HMGB1,
and CD45 expressions in a rat model subjected
to liver ischemia-reperfusion injury. J Invest
Surg 31:491–502
34. Kyriakopoulos G, Tsaroucha A, Valsami
G, Lambropoulou M, Kostomitsopoulos
N,
Christodoulou
E,
Kakazanis
Z,
Anagnostopoulos C, Tsalikidis C, Simopoulos
C (2018) Histological assessment and tissue
expression of TNF-α and M30 in the kidney
of an experimental rat model after hepatic ischemia/reperfusion and silibinin administration.
J Investig Surg 31:201–209
Neutralization and Freeze-Drying Technique to Prepare Drug: CD Complexes
hsmc.gr/wp-content/uploads/2019/02/
issue_4_2018.pdf
26. Liossi A, Ntountaniotis D, Kellici T,
Chatziathanasiadou M, Megariotis G, Mania
M, Becker-Baldus J, Kriechbaum M, Krajnc
A, Christodoulou E, Glaubitz C, Rappolt
M, Amenitsch H, Mali G, Theodorou D,
Valsami G, Pitsikalis M, Iatrou H, Tzakos A,
Mavromoustakos T (2017) Exploring the
interactions of irbesartan and irbesartan–2hydroxypropyl- β-cyclodextrin complex with
model membranes. Biochim Biophys Acta
1859:1089–1098
27. Ntountaniotis D, Andreadelis I, Kellici TF,
Karageorgos V, Leonis G, Christodoulou
E, Kiriakidi S, Becker-Baldus J, Stylos EK,
Chatziathanasiadou MV, Chatzigiannis CM,
Damalas DE, Aksoydan B, Javornik U, Valsami
G, Glaubitz C, Durdagi S, Thomaidis NS,
Kolocouris A, Plavec J, Tzakos AG, Liapakis
G, Mavromoustakos T (2019) Host-guest
interactions between candesartan and its prodrug candesartan cilexetil in complex with
2-hydroxypropyl-β-cyclodextrin: on the biological potency for Angiotensin II. Mol Pharm
16(3):1255–1271
28. Kellici TF, Ntountaniotis D, Leonis G,
Chatziathanasiadou M, Chatzikonstantinou
AV, Becker-Baldus J, Glaubitz C, Tzakos AG,
Viras K, Chatzigeorgiou P, Tzimas S, Kefala E,
Valsami G, Archontaki H, Papadopoulos MG,
Mavromoustakos T (2015) Investigation of the
interactions of silibinin with 2- hydroxypropylβ-cyclodextrin through biophysical techniques
and computational methods. Mol Pharm
12(3):954–965
29. Kellici TF, Chatziathanasiadou MV, Diamantis
D, Chatzikonstantinou AV, Andreadelis I,
Christodoulou E, Valsami G, Mavromoustakos
T, Tzakos AG (2016) Mapping the interactions and bioactivity of quercetin–
(2-hydroxypropyl)-cyclodextrin complex. Int J
Pharm 511(1):303–311
30. Diamantis DA, Ramesova S, Chatzigiannis
C, Degano I, Gerogianni P, Karadima K,
Perikleous S, Rekkas D, Gerothanassis I, Galaris
D, Mavromoustakos T, Valsami G, Sokolova R,
Tzakos A (2018) Exploring the oxidation and
iron binding profile of a cyclodextrin encapsulated quercetin complex unveiled a controlled
complex dissociation through a chemical stimulus. BBA-General Subjects 1862:1913–1924
31. Papakyriakopoulou P, Manta K, Spaneas D,
Christodoulou E, Colombo G, Rekkas D,
Dallas P, Valsami G (2019) Ex vivo transport
study on quercetin-cyclodextrin inclusion complexes as candidates for nose-to-brain delivery.
AAPS PharmSci 360:3–6
32. Christodoulou
E,
Kechagia
IA,
Kostomitsopoulos N, Balafas E, Archontaki
E, Dokoumetzidis A, Valsami G (2015)
Pharmacokinetics of silibinin after peros
and intravenous administration to mice, as a
HP-β-CD lyophilized product. Int J Pharm
493:366–373
33. Tsaroucha A, Valsami G, Kostomitsopoulos
N, Lambropoulou M, Anagnostopoulos
C, Christodoulou E, Falidas E, Betsou A,
Kakazanis Z, Pitiakoudis M, Simopoulos C
(2018) Silibinin effect on Fas/FasL, HMGB1,
and CD45 expressions in a rat model subjected
to liver ischemia-reperfusion injury. J Invest
Surg 31:491–502
34. Kyriakopoulos G, Tsaroucha A, Valsami
G, Lambropoulou M, Kostomitsopoulos
N,
Christodoulou
E,
Kakazanis
Z,
Anagnostopoulos C, Tsalikidis C, Simopoulos
C (2018) Histological assessment and tissue
expression of TNF-α and M30 in the kidney
of an experimental rat model after hepatic ischemia/reperfusion and silibinin administration.
J Investig Surg 31:201–209
Neutralization and Freeze-Drying Technique to Prepare Drug: CD Complexes