588
A. Vinothkanna and S. Sekar
Table 24.1 Patents on the diagnosis of human metabolic disorders/syndromes using PBPs as
fluorophores
Disease/diagnostic parameters
Patents-source/country and number
(A) Diagnosis of fitness or general ailments
Assessing nutritional and health status
IN 20187047753
Obesity and related disorders by adiponectin
receptor
IN 4981/DELNP/2008
Detection of increase in the level of human
tumor necrosis factor (TNF) -α indicating
disease
US 8414894
Disease related to genetic alterations
US 5665540
Multiple pathologies by toll-like receptors
IN 201617043688
Detection of sensitivity to pain (algesia)
IN 6327/CHENP/2012, IN
6328/CHENP/2012, IN 7203/CHENP/2012
Detection of pain generators
US 9757476, US 10098970
Skeletal muscle injury
US 8748104
Hereditary angioedema type III
(skin swelling on limbs, face, arms, etc.)
IN 4249/CHENP/2006
Mountain sickness
CN105385777 (E), CN105296631 (E),
CN105296630 (E), CN105219872 (E)
(B) Cardiac ailments
Cardiac arrhythmia
IN 4322/DELNP/2009
Diastolic heart failure
IN 421/DELNP/2009
Acute myocardial infarction
CN106950381 (E), CN101271108 (E)
Acute coronary syndrome
CN103163295 (E), CN103376313 (E), IN
1278/KOLNP/2009, CN102062735 (E)
Cardio vascular disease/cardiac failure
CN101825627 (E), IN 201741004864,
IN 201838007033, IN 2807/CHENP/2008
Absolute blood flow
KR 1020177012463
(C) Brain and other central nervous system-related ailments/assessments
Alzheimer’s disease
(β-peptide formation & cognitive impairment)
US 6770448, CN10246164 (E), CN107238711
(E), IN 1174/MUMNP/2012, IN
148/KOLNP/2010, IN 595/MUMNP/2012, IN
6811/CHENP/2013
Amyloid associated diseases
(Due to Type II Diabetes mellitus, Alzheimer’s
disease, prions, etc.)
IN 380/CHENP/2006
Schizophrenia (mental disorder)
CN108387743 (E), IN 227/MUMNP/2011
Multiple neurodegenerative disorders
IN 201717043447, IN 201717043449
Diagnosis of fragile X mental retardation 1
protein causing Autism
US 2014127724
Nerve imaging
US 8361775, JP2014111614 (E)
(continued)
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