7. Shamir ER et al (2014) Twist1-induced dissemination preserves epithelial identity and
requires E-cadherin. J Cell Biol 204:839–856
8. Cheung KJ et al (2016) Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell
clusters. Proc Natl Acad Sci U S A 113:
E854–E863
9. Aceto N et al (2014) Circulating tumor cell
clusters are oligoclonal precursors of breast
cancer metastasis. Cell 158:1110–1122
10. Cheung KJ, Ewald AJ (2016) A collective route
to metastasis: seeding by tumor cell clusters.
Science 352:167–169
11. Kro ¨ger C et al (2019) Acquisition of a hybrid
E/M state is essential for tumorigenicity of
basal breast cancer cells. Proc Natl Acad Sci U
S A 116:7353–7362
12. Thiery JP, Chopin D (1999) Epithelial cell
plasticity in development and tumor progression. Cancer Metastasis Rev 18(1):31–42
13. Beerling E et al (2016) Plasticity between epithelial and mesenchymal states unlinks EMT
from metastasis-enhancing stem cell capacity.
Cell Rep 14:2281–2288
14. Friedl P, Wolf K (2010) Plasticity of cell migration: a multiscale tuning model. J Cell Biol
188:11–19
15. Montell DJ et al (2012) Group choreography:
mechanisms orchestrating the collective
movement of border cells. Nat Rev Mol Cell
Biol 13:631–645
16. Montell DJ (2008) Morphogenetic cell movements: diversity from modular mechanical
properties. Science 322:1502–1505
17. Hannezo E et al (2014) Theory of epithelial
sheet morphology in three dimensions. Proc
Natl Acad Sci U S A 111:27–32
18. DiMilla PA et al (1991) Mathematical model
for the effects of adhesion and mechanics on
cell migration speed [published erratum
appears in Biophys J 1991 Oct;60(4):983].
Biophys J 60(1):15–37
19. Yamazaki D et al (2009) Involvement of Rac
and Rho signaling in cancer cell motility in 3D
substrates. Oncogene 28:1570–1583
20. Pankova ´ K et al (2010) The molecular mechanisms of transition between mesenchymal and
amoeboid invasiveness in tumor cells. Cell
Mol Life Sci 67:63–71
21. Mishra AK et al (2019) Coordination of protrusion dynamics within and between collectively migrating border cells by myosin
II. Mol Biol Cell 30(19):2490–2502. https://
doi.org/10.1091/mbc.E19-02-0124
22. L€ ammermann T, Sixt M (2009) Mechanical
modes of “amoeboid” cell migration. Curr
Opin Cell Biol 21:636–644
23. Murrell M et al (2015) Forcing cells into shape:
the mechanics of actomyosin contractility. Nat
Rev Mol Cell Biol 16:486–498
18
Denise J. Montell
requires E-cadherin. J Cell Biol 204:839–856
8. Cheung KJ et al (2016) Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell
clusters. Proc Natl Acad Sci U S A 113:
E854–E863
9. Aceto N et al (2014) Circulating tumor cell
clusters are oligoclonal precursors of breast
cancer metastasis. Cell 158:1110–1122
10. Cheung KJ, Ewald AJ (2016) A collective route
to metastasis: seeding by tumor cell clusters.
Science 352:167–169
11. Kro ¨ger C et al (2019) Acquisition of a hybrid
E/M state is essential for tumorigenicity of
basal breast cancer cells. Proc Natl Acad Sci U
S A 116:7353–7362
12. Thiery JP, Chopin D (1999) Epithelial cell
plasticity in development and tumor progression. Cancer Metastasis Rev 18(1):31–42
13. Beerling E et al (2016) Plasticity between epithelial and mesenchymal states unlinks EMT
from metastasis-enhancing stem cell capacity.
Cell Rep 14:2281–2288
14. Friedl P, Wolf K (2010) Plasticity of cell migration: a multiscale tuning model. J Cell Biol
188:11–19
15. Montell DJ et al (2012) Group choreography:
mechanisms orchestrating the collective
movement of border cells. Nat Rev Mol Cell
Biol 13:631–645
16. Montell DJ (2008) Morphogenetic cell movements: diversity from modular mechanical
properties. Science 322:1502–1505
17. Hannezo E et al (2014) Theory of epithelial
sheet morphology in three dimensions. Proc
Natl Acad Sci U S A 111:27–32
18. DiMilla PA et al (1991) Mathematical model
for the effects of adhesion and mechanics on
cell migration speed [published erratum
appears in Biophys J 1991 Oct;60(4):983].
Biophys J 60(1):15–37
19. Yamazaki D et al (2009) Involvement of Rac
and Rho signaling in cancer cell motility in 3D
substrates. Oncogene 28:1570–1583
20. Pankova ´ K et al (2010) The molecular mechanisms of transition between mesenchymal and
amoeboid invasiveness in tumor cells. Cell
Mol Life Sci 67:63–71
21. Mishra AK et al (2019) Coordination of protrusion dynamics within and between collectively migrating border cells by myosin
II. Mol Biol Cell 30(19):2490–2502. https://
doi.org/10.1091/mbc.E19-02-0124
22. L€ ammermann T, Sixt M (2009) Mechanical
modes of “amoeboid” cell migration. Curr
Opin Cell Biol 21:636–644
23. Murrell M et al (2015) Forcing cells into shape:
the mechanics of actomyosin contractility. Nat
Rev Mol Cell Biol 16:486–498
18
Denise J. Montell