52
L. Quadro and E. K. Spiegler
Kim YK, Zuccaro MV, Costabile BK, Rodas R, Quadro L (2015) Tissue- and sex-specific effects of
beta-carotene 15,15 oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing
mice. Arch Biochem Biophys 572:11–18
Kochhar DM (1976) Transplacental passage of label after administration of (3H) retinoic acid
(vitamin A acid) to pregnant mice. Teratology 1976(14):53–63
Kopec RE, Riedl KM, Harrison EH, Curley RWJr, Hruszkewycz DP Clinton SK, Schwartz SJ (2010)
Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma. J
Agric Food Chem 58:3290–3296
Kraft JC, Kochhar DM, Scott WJ, Nau H (1987) Low teratogenicity of 13-cis-retinoic acid
(isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis:
comparison to the all-trans isomer. Toxicol Appl Pharmacol 87:474–482
Kushtagi P, Arvapally S (2009) Maternal mid-pregnancy serum triglyceride levels and neonatal
birth weight. Int J Gynaecol Obstet 106:258–259
Lee SA, Jiang H, Trent CM, Yuen JJ, Narayanasamy S, Curley RW Jr, Harrison EH, Goldberg
IJ, Maurer MS, Blaner WS (2014) Cardiac dysfunction in beta-carotene-15,15 -dioxygenasedeficient mice is associated with altered retinoid and lipid metabolism. Am J Physiol Heart Circ
Physiol 301:H1675–H1684
Levak-Frank S, Radner H, Walsh A, Stollberger R, Knipping G, Hoefler G, Sattler W, Weinstock
PH, Breslow JL, Zechner R (1995) Muscle-specific overexpression of lipoprotein lipase causes
a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic
mice. J Clin Invest 96:976–986
Liu KH, Baumbach GA, Gillevet PM, Godkin JD (1990) Purification and characterization of bovine
placental retinol-binding protein. Endocrinology 127:2696–2704
Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J (2013) Genetics and diet
regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem 288:9017–
9027
Love AM, Vickers TH (1976) Placental agenesis, embryonal hydraemia, embryolethality and acute
hypervitaminosis A in rats. Br J Exp Pathol 57:525–541
Madsen EM, Lindegaard ML, Andersen CB, Damm P, Nielsen LB (2004) Human placenta secretes
apolipoprotein B-100-containing lipoproteins. J Biol Chem 279:55271–55276
Mason KE (1935) Foetal death, prolonged gestation and difficult parturition in the rat as result of
vitamin A. Am J Anat 57:303–349
McCollum EV, Davis M (1913) The necessity of certain lipins in the diet during growth. J Biol
Chem 15:167–175
Merkel M, Eckel RH, Goldberg IJ (2002) Lipoprotein lipase: genetics, lipid uptake, and regulation.
J Lipid Res 43:1997–2006
Mitchell GE, Rattray PV, Hutton JB (1975) Vitamin A alcohol and vitamin A palmitate transfer
from ewes to lambs. Int J Vitam Nutr Res 45:299–304
Moore T (1971) Vitamin A transfer from mother to offspring in mice and rats. Int J Vitam Nutr Res
41:301–306
Morriss GM (1973) An electron microscopic study of the effects of hypervitaminosis A on the
maternal-embryonic relationship of the rat at 8 days of pregnancy. J Reprod Fertil 33:451–456
Nadeau V, Charron J (2014) Essential role of the ERK/MAPK pathway in blood-placental barrier
formation. Development 141:2825–2837
Noy N (2016) Vitamin A transport and cell signaling by the retinol-binding protein receptor STRA6.
Subcell Biochem 81:77–93
O’Byrne SM, Blaner WS (2013) Retinol and retinyl esters: biochemistry and physiology. J Lipid
Res 54:1731–1743
Okuda Y (1960) Histochemical studies on the metabolism of fat and vitamin A of placenta. Tohoku
J Exp Med 72:290–300
Palczewski G, Widjaja-Adhi MA, Amengual J, Golczak M, von Lintig J (2016) Genetic dissection
in a mouse model reveals interactions between carotenoids and lipid metabolism. J Lipid Res
57:1684–1695
L. Quadro and E. K. Spiegler
Kim YK, Zuccaro MV, Costabile BK, Rodas R, Quadro L (2015) Tissue- and sex-specific effects of
beta-carotene 15,15 oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing
mice. Arch Biochem Biophys 572:11–18
Kochhar DM (1976) Transplacental passage of label after administration of (3H) retinoic acid
(vitamin A acid) to pregnant mice. Teratology 1976(14):53–63
Kopec RE, Riedl KM, Harrison EH, Curley RWJr, Hruszkewycz DP Clinton SK, Schwartz SJ (2010)
Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma. J
Agric Food Chem 58:3290–3296
Kraft JC, Kochhar DM, Scott WJ, Nau H (1987) Low teratogenicity of 13-cis-retinoic acid
(isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis:
comparison to the all-trans isomer. Toxicol Appl Pharmacol 87:474–482
Kushtagi P, Arvapally S (2009) Maternal mid-pregnancy serum triglyceride levels and neonatal
birth weight. Int J Gynaecol Obstet 106:258–259
Lee SA, Jiang H, Trent CM, Yuen JJ, Narayanasamy S, Curley RW Jr, Harrison EH, Goldberg
IJ, Maurer MS, Blaner WS (2014) Cardiac dysfunction in beta-carotene-15,15 -dioxygenasedeficient mice is associated with altered retinoid and lipid metabolism. Am J Physiol Heart Circ
Physiol 301:H1675–H1684
Levak-Frank S, Radner H, Walsh A, Stollberger R, Knipping G, Hoefler G, Sattler W, Weinstock
PH, Breslow JL, Zechner R (1995) Muscle-specific overexpression of lipoprotein lipase causes
a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic
mice. J Clin Invest 96:976–986
Liu KH, Baumbach GA, Gillevet PM, Godkin JD (1990) Purification and characterization of bovine
placental retinol-binding protein. Endocrinology 127:2696–2704
Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J (2013) Genetics and diet
regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem 288:9017–
9027
Love AM, Vickers TH (1976) Placental agenesis, embryonal hydraemia, embryolethality and acute
hypervitaminosis A in rats. Br J Exp Pathol 57:525–541
Madsen EM, Lindegaard ML, Andersen CB, Damm P, Nielsen LB (2004) Human placenta secretes
apolipoprotein B-100-containing lipoproteins. J Biol Chem 279:55271–55276
Mason KE (1935) Foetal death, prolonged gestation and difficult parturition in the rat as result of
vitamin A. Am J Anat 57:303–349
McCollum EV, Davis M (1913) The necessity of certain lipins in the diet during growth. J Biol
Chem 15:167–175
Merkel M, Eckel RH, Goldberg IJ (2002) Lipoprotein lipase: genetics, lipid uptake, and regulation.
J Lipid Res 43:1997–2006
Mitchell GE, Rattray PV, Hutton JB (1975) Vitamin A alcohol and vitamin A palmitate transfer
from ewes to lambs. Int J Vitam Nutr Res 45:299–304
Moore T (1971) Vitamin A transfer from mother to offspring in mice and rats. Int J Vitam Nutr Res
41:301–306
Morriss GM (1973) An electron microscopic study of the effects of hypervitaminosis A on the
maternal-embryonic relationship of the rat at 8 days of pregnancy. J Reprod Fertil 33:451–456
Nadeau V, Charron J (2014) Essential role of the ERK/MAPK pathway in blood-placental barrier
formation. Development 141:2825–2837
Noy N (2016) Vitamin A transport and cell signaling by the retinol-binding protein receptor STRA6.
Subcell Biochem 81:77–93
O’Byrne SM, Blaner WS (2013) Retinol and retinyl esters: biochemistry and physiology. J Lipid
Res 54:1731–1743
Okuda Y (1960) Histochemical studies on the metabolism of fat and vitamin A of placenta. Tohoku
J Exp Med 72:290–300
Palczewski G, Widjaja-Adhi MA, Amengual J, Golczak M, von Lintig J (2016) Genetic dissection
in a mouse model reveals interactions between carotenoids and lipid metabolism. J Lipid Res
57:1684–1695