8 Fetal Alcohol Spectrum Disorder: Embryogenesis Under …
219
Jones KL, Smith DW (1973) Recognition of the fetal alcohol syndrome in early infancy. The Lancet
302:999–1001
Jones KL, Smith DW, Ulleland CN, Streissguth P (1973) Pattern of malformation in offspring of
chronic alcoholic mothers. The Lancet 1:1267–1271
Joya X, Garcia-Algar O, Salat-Batlle J, Pujades C, Vall O (2015) Advances in the development of
novel antioxidant therapies as an approach for fetal alcohol syndrome prevention. Birth Defects
Res Part A Clin Mol Teratol 103:163–177
Jun S-R, Wassenaar TM, Wanchai V, Patumcharoenpol P, Nookaew I, Ussery DW (2017) Suggested
mechanisms for Zika virus causing microcephaly: what do the genomes tell us? BMC Bioinform
18:471
Kalisch-Smith JI, Moritz KM (2018) Detrimental effects of alcohol exposure around conception:
putative mechanisms. Biochem Cell Biol (Biochim et Biol Cell) 96:107–116
Kane CJM, Drew PD (2016) Inflammatory responses to alcohol in the CNS: nuclear receptors as
potential therapeutics for alcohol-induced neuropathologies. J Leukoc Biol 100:951–959
Kedishvili NY (2013) Enzymology of retinoic acid biosynthesis and degradation. J Lipid Res
54:1744–1760
Kedishvili NY, Gough WH, Davis WI, Parsons S, Li TK, Bosron WF (1998) Effect of cellular
retinol-binding protein on retinol oxidation by human class IV retinol/alcohol dehydrogenase
and inhibition by ethanol. Biochem Biophys Res Commun 249:191–196
Kennerknecht I, Sorgo W, Oberhoffer R, Teller WM, Mattfeldt T, Negri G, Vogel W (1993) Familial
occurrence of agonadism and multiple internal malformations in phenotypically normal girls with
46, XY and 46, XX karyotypes, respectively: a new autosomal recessive syndrome. Am J Med
Genet 47:1166–1170
Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ (2002a) Moderate alcohol intake
during pregnancy and the risk of stillbirth and death in the first year of life. Am J Epidemiol
155:305–312
Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ (2002b) Moderate alcohol intake in
pregnancy and the risk of spontaneous abortion. Alcohol Alcohol (Oxford, Oxfordshire) 37:87–92
Kikonyogo A, Abriola DP, Dryjanski M, Pietruszko R (1999) Mechanism of inhibition of aldehyde
dehydrogenase by citral, a retinoid antagonist. Eur J Biochem/FEBS 262:704–712
Koide T, Downes M, Chandraratna RA, Blumberg B, Umesono K (2001) Active repression of RAR
signaling is required for head formation. Genes Dev 15:2111–2121
Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D
et al (2012) Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology,
mechanism of action, substrate specificity, and clinical application. Pharmacol Rev 64:520–539
Koren G, Nulman I, Chudley AE, Loocke C (2003) Fetal alcohol spectrum disorder. Can Med Assoc
J 169:1181–1185
Kot-Leibovich H, Fainsod A (2009) Ethanol induces embryonic malformations by competing for
retinaldehyde dehydrogenase activity during vertebrate gastrulation. Dis Model Mech 2:295–305
Kraft JC, Schuh T, Juchau M, Kimelman D (1994) The retinoid X receptor ligand, 9-cis-retinoic acid,
is a potential regulator of early Xenopus development. Proc Natl Acad Sci USA 91:3067–3071
Kraft JC, Kimelman D, Juchau MR (1995) Xenopus laevis: a model system for the study of embryonic retinoid metabolism. I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols
to their corresponding acid forms. Drug Metab Dispos: Biol Fate Chem 23:72–82
Krivospitskaya O, Elmabsout AA, Sundman E, Söderström LA, Ovchinnikova O, Gidlöf AC,
Scherbak N et al (2012) A CYP26B1 polymorphism enhances retinoic acid catabolism and may
aggravate atherosclerosis. Mol Med 18:712–718
Kumar S, Sandell LL, Trainor PA, Koentgen F, Duester G (2012) Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models. Biochem Biophys Acta
1821:198–205
Kumar A, Singh HN, Pareek V, Raza K, Dantham S, Kumar P, Mochan S et al (2016) A possible mechanism of zika virus associated microcephaly: imperative role of retinoic acid response
element (RARE) consensus sequence repeats in the viral genome. Front Hum Neurosci 10:403
219
Jones KL, Smith DW (1973) Recognition of the fetal alcohol syndrome in early infancy. The Lancet
302:999–1001
Jones KL, Smith DW, Ulleland CN, Streissguth P (1973) Pattern of malformation in offspring of
chronic alcoholic mothers. The Lancet 1:1267–1271
Joya X, Garcia-Algar O, Salat-Batlle J, Pujades C, Vall O (2015) Advances in the development of
novel antioxidant therapies as an approach for fetal alcohol syndrome prevention. Birth Defects
Res Part A Clin Mol Teratol 103:163–177
Jun S-R, Wassenaar TM, Wanchai V, Patumcharoenpol P, Nookaew I, Ussery DW (2017) Suggested
mechanisms for Zika virus causing microcephaly: what do the genomes tell us? BMC Bioinform
18:471
Kalisch-Smith JI, Moritz KM (2018) Detrimental effects of alcohol exposure around conception:
putative mechanisms. Biochem Cell Biol (Biochim et Biol Cell) 96:107–116
Kane CJM, Drew PD (2016) Inflammatory responses to alcohol in the CNS: nuclear receptors as
potential therapeutics for alcohol-induced neuropathologies. J Leukoc Biol 100:951–959
Kedishvili NY (2013) Enzymology of retinoic acid biosynthesis and degradation. J Lipid Res
54:1744–1760
Kedishvili NY, Gough WH, Davis WI, Parsons S, Li TK, Bosron WF (1998) Effect of cellular
retinol-binding protein on retinol oxidation by human class IV retinol/alcohol dehydrogenase
and inhibition by ethanol. Biochem Biophys Res Commun 249:191–196
Kennerknecht I, Sorgo W, Oberhoffer R, Teller WM, Mattfeldt T, Negri G, Vogel W (1993) Familial
occurrence of agonadism and multiple internal malformations in phenotypically normal girls with
46, XY and 46, XX karyotypes, respectively: a new autosomal recessive syndrome. Am J Med
Genet 47:1166–1170
Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ (2002a) Moderate alcohol intake
during pregnancy and the risk of stillbirth and death in the first year of life. Am J Epidemiol
155:305–312
Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ (2002b) Moderate alcohol intake in
pregnancy and the risk of spontaneous abortion. Alcohol Alcohol (Oxford, Oxfordshire) 37:87–92
Kikonyogo A, Abriola DP, Dryjanski M, Pietruszko R (1999) Mechanism of inhibition of aldehyde
dehydrogenase by citral, a retinoid antagonist. Eur J Biochem/FEBS 262:704–712
Koide T, Downes M, Chandraratna RA, Blumberg B, Umesono K (2001) Active repression of RAR
signaling is required for head formation. Genes Dev 15:2111–2121
Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D
et al (2012) Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology,
mechanism of action, substrate specificity, and clinical application. Pharmacol Rev 64:520–539
Koren G, Nulman I, Chudley AE, Loocke C (2003) Fetal alcohol spectrum disorder. Can Med Assoc
J 169:1181–1185
Kot-Leibovich H, Fainsod A (2009) Ethanol induces embryonic malformations by competing for
retinaldehyde dehydrogenase activity during vertebrate gastrulation. Dis Model Mech 2:295–305
Kraft JC, Schuh T, Juchau M, Kimelman D (1994) The retinoid X receptor ligand, 9-cis-retinoic acid,
is a potential regulator of early Xenopus development. Proc Natl Acad Sci USA 91:3067–3071
Kraft JC, Kimelman D, Juchau MR (1995) Xenopus laevis: a model system for the study of embryonic retinoid metabolism. I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols
to their corresponding acid forms. Drug Metab Dispos: Biol Fate Chem 23:72–82
Krivospitskaya O, Elmabsout AA, Sundman E, Söderström LA, Ovchinnikova O, Gidlöf AC,
Scherbak N et al (2012) A CYP26B1 polymorphism enhances retinoic acid catabolism and may
aggravate atherosclerosis. Mol Med 18:712–718
Kumar S, Sandell LL, Trainor PA, Koentgen F, Duester G (2012) Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models. Biochem Biophys Acta
1821:198–205
Kumar A, Singh HN, Pareek V, Raza K, Dantham S, Kumar P, Mochan S et al (2016) A possible mechanism of zika virus associated microcephaly: imperative role of retinoic acid response
element (RARE) consensus sequence repeats in the viral genome. Front Hum Neurosci 10:403