Drug candidate
Condition treated
RVX000222/
RVX208
Cardiovascular disease
GSK525762/I-BET-762/iBET
Breast and prostate cancer
NUT midline carcinoma
ABBV-075
Breast cancer
Non-small cell lung cancer
OTX105/OTX015MK8628
NUT midline carcinoma
Triple negative breast cancer
Solid tumors
CPI-0610
Multiple myeloma
Leukemia
Myelofibrosis
BMS-986158
Advanced tumors
RO6870810
Acute myeloid leukemia
Ovarian and breast cancers
Solid tumors
GSK2820151
Solid tumors
CC-900010
Lymphomas
BAY 1238097
Neoplasms
ZEN003694
Metastatic castration-resistant
prostate cancer
INCB054329
Solid tumors and
hematologic malignancy
INCB057643
Solid tumors and
hematologic malignancy
Fig. 7 Bromodomain
inhibitors in clinical trials
and their respective targeted
disease states
Applied Biophysics for Bromodomain Drug Discovery
305