MAP 3K2
Mitogen-activated protein kinase kinase kinase 2
MCF10A
Non-tumorigenic epithelial cell line
MCF7
Breast cancer cell line
MDA-MB-231
Human breast cancer cell line
MLL
Mixed-lineage leukemia
MOA
Mechanism of action
MV4–11 (MLL-AF4),
MOLM-13 (MLL-AF9),
and THP1 (MLL-AF9)
MLL-rearranged cell lines
MYND
Myeloid translocation protein-8, Nervy, and DEAF-1
PARP1
Poly(ADP-ribose)-polymerase 1
PC-3
Prostate cancer cell line
PCNA
Proliferating cell nuclear antigen
PK
Physical-chemical (properties)
PKMTs
Protein lysine methyltransferases
PML-NB
Promyelocytic leukemia protein nuclear bodies
PMTs
Protein methyltransferases
PPAR-γ
Peroxisome proliferator-activated receptor gamma
PPI
Protein-protein interaction
PRC2
Polycomb-repressive complex 2
PRMTs
Protein arginine methyltransferases
PWS
Prader-Willi syndrome
Rb
Retinoblastoma
RBBP5
Retinoblastoma-binding protein 5
RE-IIBP
Response element II-binding protein
RNMTs
RNA methyltransferases
SAH
S-adenosyl homocysteine
SAM
S-adenosyl-L-methionine
SAR
Structure-activity relationship
SCD
Sickle cell disease
SCLC
Small cell lung cancer
SET
Nuclear proto-oncogene
SETD2
SET domain containing 2 histone methyltransferase
SETD7
SET domain containing 7 histone methyltransferase
SETD8
SET domain containing 8 histone methyltransferase
SETDB1
SET domain bifurcated 1
SMYD
SET and MYND domain-containing
SUM159
Breast cancer cell line
SUV
Histone-lysine N-methyltransferase
SUZ12
Subunit polycomb-repressive complex 2
U2OS
Osteosarcoma cell line
U937
Histiocytic lymphoma cell line
VEGFR1
Vascular endothelial growth factor receptor 1
WDR5
WD repeat-containing protein 5
WT
Wild type
Lysine Methyltransferases and Their Inhibitors
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