l
The mechanism involved in biosynthesis and regulation of possible metabolites having insecticidal properties is an essential role
in nematode–bacteria [104].
l
They possess a broad spectrum of bioactivities of agricultural
and medicinal interest, like antibiotic, antimycotic, antiviral,
insecticidal, nematicidal, antiulcer, and antineoplastic.
l
The antibiotic action is effective toward microorganisms of the
Gram-positive Micrococcus, Staphylococcus, and Bacillus; the
Gram-negative Escherichia, Shigella, Enterobacter, Serratia, Proteus, Erwinia, Flavobacterium, and Pseudomonas; and the yeasts
Candida and Saccharomyces [105].
l
Antimycotic activity is effective in a number of fungi including
Botrytis cinerea, Fusarium oxysporum, Fusarium solani, Mucor
piriformis, Pythium coloratum, Pythium ultimum, Penicillium
spp., Rhizoctonia solani, Trichoderma pseudokoningii, and Verticillium dahliae.
l
Xenocoumacin doses given orally to rats show potent activity
toward stress-induced ulcers [102].
l
The
compound
protein
CyA
is
responsible
for
cytotoxicity [106].
Fig. 1 (continued)
Bacterial Metabolites
23