Contents
1 Introduction of Aptamer, SELEX, and Different SELEX
Variants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1
Liling Hao and Huajie Gu
2 Aptamer-Based Probes for Molecular Imaging . . . . . . . . . . . . . . . . . . . 31
Dengfeng Li, Yesi Shi, and Gang Liu
3 Aptamer-Based Point of Care Testing Schemes . . . . . . . . . . . . . . . . . . . 53
Ghulam Murtaza, Aysha Sarfraz Rizvi, and Feng Qu
4 Aptamer-Based Drug Delivery Systems . . . . . . . . . . . . . . . . . . . . . . . . . . 77
Zhenbao Liu and Yanfei Liu
5 Aptamer-Based Medical Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Boshi Liu, Haixia Wang, and Di Zhang
6 Aptamers for Targeted Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
Ge Yang and Yuanyu Huang
7 Aptamers for Personalized Therapeutics . . . . . . . . . . . . . . . . . . . . . . . . 179
Muhammad Irfan, Rizwan Ullah Khan, and Feng Qu
8 Aptamers for the Diagnosis of Infectious Diseases . . . . . . . . . . . . . . . . 207
Ting Zhang, Yunhao Lu, Sha Deng, and Ruijie Deng
9 Aptamers for the Diagnosis of Malign Tumors . . . . . . . . . . . . . . . . . . . 239
Qiyan Lv, Huifang Cui, and Xiaojie Song
10 Aptamers for Thrombotic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279
Weibin Li, Shenghang Zhang, Meng Zhao, and Xiaopeng Lan
11 Hormone Aptamers in Endocrine-Related Diseases . . . . . . . . . . . . . . . 319
Yan Cheng and Hongyan Jin
12 Aptamers for the Diagnosis and Therapy of Neurodegenerative
Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351
Jing Qu and Jianliang Zhang
xi