3 Aptamer-Based Point of Care Testing Schemes
73
20. Wang F, Gopinath SCB, Lakshmipriya T (2019) Aptamer-antibody complementation on
multiwalled carbon nanotube-gold transduced dielectrode surfaces to detect pandemic swine
influenza virus. Int J Nanomedicine 14:8469–8481. https://doi.org/10.2147/IJN.S219976
21. Zhao B, Wu P, Zhang H, Cai C (2015) Designing activatable aptamer probes for simultaneous
detection of multiple tumor-related proteins in living cancer cells. Biosens Bioelectron 68:763–
770. https://doi.org/10.1016/j.bios.2015.02.004
22. Wang K, Fan D, Liu Y, Wang E (2015) Highly sensitive and specific colorimetric detection of
cancer cells via dual-aptamer target binding strategy. Biosens Bioelectron 73:1–6. https://doi.
org/10.1016/j.bios.2015.05.044
23. Wang CH, Wu JJ, Bin LG (2019) Screening of highly-specific aptamers and their applications
in paper-based microfluidic chips for rapid diagnosis of multiple bacteria. Sens Actuat B Chem
284:395–402. https://doi.org/10.1016/j.snb.2018.12.112
24. Kim SH, Lee J, Lee BH et al (2019) Specific detection of avian influenza H5N2 whole virus
particles on lateral flow strips using a pair of sandwich-type aptamers. Biosens Bioelectron
134:123–129. https://doi.org/10.1016/j.bios.2019.03.061
25. Lin B, Yu Y, Cao Y et al (2018) Point-of-care testing for streptomycin based on aptamer
recognizing and digital image colorimetry by smartphone. Biosens Bioelectron 100:482–489.
https://doi.org/10.1016/j.bios.2017.09.028
26. Lee S, O’Dell D, Hohenstein J et al (2016) NutriPhone: a mobile platform for low-cost pointof-care quantification of Vitamin B 12 concentrations. Sci Rep 6:28237. https://doi.org/10.
1038/srep28237
27. Zhu H, Sencan I, Wong J et al (2013) Cost-effective and rapid blood analysis on a cell-phone.
Lab Chip 13:1282–1288. https://doi.org/10.1039/c3lc41408f
28. Zhang Y, Ma CB, Yang M et al (2019) Point-of-care testing of various analytes by means of
a one-step competitive displacement reaction and pregnancy test strips. Sens Actuat B Chem
288:163–170. https://doi.org/10.1016/j.snb.2019.02.091
29. Tang MSL, Shiu SCC, Godonoga M et al (2018) An aptamer-enabled DNA nanobox for protein
sensing. Nanomed Nanotechnol Biol Med 14:1161–1168. https://doi.org/10.1016/j.nano.2018.
01.018
30. Godonoga M, Lin TY, Oshima A et al (2016) A DNA aptamer recognising a malaria protein
biomarker can function as part of a DNA origami assembly. Sci Rep 6. https://doi.org/10.1038/
srep21266
31. Jin B, Yang Y, He R et al (2018) Lateral flow aptamer assay integrated smartphone-based
portable device for simultaneous detection of multiple targets using upconversion nanoparticles.
Sens Actuat B Chem 276:48–56. https://doi.org/10.1016/j.snb.2018.08.074
32. Xing X, Liu X, Zhou Y et al (2016) Graphene oxide enhanced specificity at aptamer and its
application to multiplexed enzymatic activity sensing. RSC Adv 6:11815–11821. https://doi.
org/10.1039/c5ra25481g
33. Luo F, Zheng L, Chen S et al (2012) An aptamer-based fluorescence biosensor for multiplex
detection using unmodified gold nanoparticles. Chem Commun 48:6387–6389. https://doi.org/
10.1039/c2cc32667a
34. Raeisossadati MJ, Danesh NM, Borna F et al (2016) Lateral flow based immunobiosensors for
detection of food contaminants. Biosens Bioelectron 86:235–246
35. Dhiman A, Kalra P, Bansal V, Bruno JG, Sharma TK (2017) Aptamer-based point-of-care
diagnostic platforms. Sens Actuat B: Chem 246:535–553. https://doi.org/10.1016/j.snb.2017.
02.060
36. Bahadır EB, Sezgintürk MK (2016) Lateral flow assays: principles, designs and labels. TrAC—
Trends Anal Chem 82:286–306
37. Dalirirad S, Steckl AJ (2019) Aptamer-based lateral flow assay for point of care cortisol
detection in sweat. Sens Actuat B Chem 283:79–86. https://doi.org/10.1016/j.snb.2018.11.161
38. Liu G, Mao X, Phillips JA et al (2009) Aptamer−nanoparticle strip biosensor for sensitive
detection of cancer cells. Anal Chem 81:10013–10018. https://doi.org/10.1021/ac901889s
39. Mukama O, Wu W, Wu J et al (2020) A highly sensitive and specific lateral flow aptasensor for
the detection of human osteopontin. Talanta 210. https://doi.org/10.1016/j.talanta.2019.120624
73
20. Wang F, Gopinath SCB, Lakshmipriya T (2019) Aptamer-antibody complementation on
multiwalled carbon nanotube-gold transduced dielectrode surfaces to detect pandemic swine
influenza virus. Int J Nanomedicine 14:8469–8481. https://doi.org/10.2147/IJN.S219976
21. Zhao B, Wu P, Zhang H, Cai C (2015) Designing activatable aptamer probes for simultaneous
detection of multiple tumor-related proteins in living cancer cells. Biosens Bioelectron 68:763–
770. https://doi.org/10.1016/j.bios.2015.02.004
22. Wang K, Fan D, Liu Y, Wang E (2015) Highly sensitive and specific colorimetric detection of
cancer cells via dual-aptamer target binding strategy. Biosens Bioelectron 73:1–6. https://doi.
org/10.1016/j.bios.2015.05.044
23. Wang CH, Wu JJ, Bin LG (2019) Screening of highly-specific aptamers and their applications
in paper-based microfluidic chips for rapid diagnosis of multiple bacteria. Sens Actuat B Chem
284:395–402. https://doi.org/10.1016/j.snb.2018.12.112
24. Kim SH, Lee J, Lee BH et al (2019) Specific detection of avian influenza H5N2 whole virus
particles on lateral flow strips using a pair of sandwich-type aptamers. Biosens Bioelectron
134:123–129. https://doi.org/10.1016/j.bios.2019.03.061
25. Lin B, Yu Y, Cao Y et al (2018) Point-of-care testing for streptomycin based on aptamer
recognizing and digital image colorimetry by smartphone. Biosens Bioelectron 100:482–489.
https://doi.org/10.1016/j.bios.2017.09.028
26. Lee S, O’Dell D, Hohenstein J et al (2016) NutriPhone: a mobile platform for low-cost pointof-care quantification of Vitamin B 12 concentrations. Sci Rep 6:28237. https://doi.org/10.
1038/srep28237
27. Zhu H, Sencan I, Wong J et al (2013) Cost-effective and rapid blood analysis on a cell-phone.
Lab Chip 13:1282–1288. https://doi.org/10.1039/c3lc41408f
28. Zhang Y, Ma CB, Yang M et al (2019) Point-of-care testing of various analytes by means of
a one-step competitive displacement reaction and pregnancy test strips. Sens Actuat B Chem
288:163–170. https://doi.org/10.1016/j.snb.2019.02.091
29. Tang MSL, Shiu SCC, Godonoga M et al (2018) An aptamer-enabled DNA nanobox for protein
sensing. Nanomed Nanotechnol Biol Med 14:1161–1168. https://doi.org/10.1016/j.nano.2018.
01.018
30. Godonoga M, Lin TY, Oshima A et al (2016) A DNA aptamer recognising a malaria protein
biomarker can function as part of a DNA origami assembly. Sci Rep 6. https://doi.org/10.1038/
srep21266
31. Jin B, Yang Y, He R et al (2018) Lateral flow aptamer assay integrated smartphone-based
portable device for simultaneous detection of multiple targets using upconversion nanoparticles.
Sens Actuat B Chem 276:48–56. https://doi.org/10.1016/j.snb.2018.08.074
32. Xing X, Liu X, Zhou Y et al (2016) Graphene oxide enhanced specificity at aptamer and its
application to multiplexed enzymatic activity sensing. RSC Adv 6:11815–11821. https://doi.
org/10.1039/c5ra25481g
33. Luo F, Zheng L, Chen S et al (2012) An aptamer-based fluorescence biosensor for multiplex
detection using unmodified gold nanoparticles. Chem Commun 48:6387–6389. https://doi.org/
10.1039/c2cc32667a
34. Raeisossadati MJ, Danesh NM, Borna F et al (2016) Lateral flow based immunobiosensors for
detection of food contaminants. Biosens Bioelectron 86:235–246
35. Dhiman A, Kalra P, Bansal V, Bruno JG, Sharma TK (2017) Aptamer-based point-of-care
diagnostic platforms. Sens Actuat B: Chem 246:535–553. https://doi.org/10.1016/j.snb.2017.
02.060
36. Bahadır EB, Sezgintürk MK (2016) Lateral flow assays: principles, designs and labels. TrAC—
Trends Anal Chem 82:286–306
37. Dalirirad S, Steckl AJ (2019) Aptamer-based lateral flow assay for point of care cortisol
detection in sweat. Sens Actuat B Chem 283:79–86. https://doi.org/10.1016/j.snb.2018.11.161
38. Liu G, Mao X, Phillips JA et al (2009) Aptamer−nanoparticle strip biosensor for sensitive
detection of cancer cells. Anal Chem 81:10013–10018. https://doi.org/10.1021/ac901889s
39. Mukama O, Wu W, Wu J et al (2020) A highly sensitive and specific lateral flow aptasensor for
the detection of human osteopontin. Talanta 210. https://doi.org/10.1016/j.talanta.2019.120624