12 Aptamers for the Diagnosis and Therapy …
367
Table 12.4
Aptamer sequences against HD biomarkers
Targets Source Aptamer sequences (5
-3
)
References
mHTT DNA
GGGGGGGGGGGGGGGGGGGG
[105]
mHTT RNA
GGGAGAGAGAGACAGUCUGCAGUUAAGGCUCCGCACAGACAAACAUACAAGCCCCAAGCAACGUCAACUCCAGAA [103, 106]
mHTT DNA
AGGGGTGGGGAGGGGTGGGGA
AGGGGTGGGGAGGGGAGGGGA
GGGAGGGAGGGAGGGAGGGAGGGAGGGAGGGAGGGA
TGGGGAGGGGAGGGGCGGGGT
[104]