11 Hormone Aptamers in Endocrine-Related Diseases
345
13. Akki SU, Werth CJ, Silverman SK (2015) Selective aptamers for detection of estradiol and
ethynylestradiol in natural waters. Environ Sci Technol 49(16):9905–9913. https://doi.org/
10.1021/acs.est.5b02401
14. Vanschoenbeek K, Vanbrabant J, Hosseinkhani B, Vermeeren V, Michiels L (2015) Aptamers
targeting different functional groups of 17β-estradiol. J Steroid Biochem Mol Biol 147:10–16.
https://doi.org/10.1016/j.jsbmb.2014.10.013
15. Svobodová M, Skouridou V, Botero ML, Jauset-Rubio M, Schubert T, Bashammakh AS,
El-Shahawi MS, Alyoubi AO, O’Sullivan CK (2017) The characterization and validation of
17β-estradiol binding aptamers. J Steroid Biochem Mol Biol 167:14–22. https://doi.org/10.
1016/j.jsbmb.2016.09.018
16. Kim JY, Park JH, Kim MI, Lee HH, Kim HL, Jeong KS, Moon SO, Kang PW, Park KW, Lee
YH, Chun BW (2018) Identification of female-specific blood stains using a 17β-estradioltargeted aptamer-based sensor. Int J Legal Med 132(1):91–98. https://doi.org/10.1007/s00
414-017-1718-z
17. Huang H, Shi S, Gao X, Gao R, Zhu Y, Wu X, Zang R, Yao T (2016) A universal labelfree fluorescent aptasensor based on Ru complex and quantum dots for adenosine, dopamine
and 17β-estradiol detection. Biosens Bioelectron 79:198–204. https://doi.org/10.1016/j.bios.
2015.12.024
18. Yao L, Li Y, Cheng K, Pan D, Xu J, Chen W (2019) Determination of 17β-estradiol by
surface-enhanced Raman spectroscopy merged with hybridization chain reaction amplification on Au@Ag core-shell nanoparticles. Mikrochim Acta 186(2):52. https://doi.org/10.1007/
s00604-018-3114-x
19. Ming T, Wang Y, Luo J, Liu J, Sun S, Xing Y, Xiao G, Jin H, Cai X (2019) Folding paperbased aptasensor platform coated with novel nanoassemblies for instant and highly sensitive
detection of 17beta-Estradiol. ACS Sens 4(12):3186–3194. https://doi.org/10.1021/acssen
sors.9b01633
20. Contreras Jiménez G, Eissa S, Ng A, Alhadrami H, Zourob M, Siaj M (2015) Aptamer-based
label-free impedimetric biosensor for detection of progesterone. Anal Chem 87(2):1075–
1082. https://doi.org/10.1021/ac503639s
21. Alhadrami HA, Chinnappan R, Eissa S, Rahamn AA, Zourob M (2017) High affinity truncated
DNA aptamers for the development of fluorescence based progesterone biosensors. Anal
Biochem 525:78–84. https://doi.org/10.1016/j.ab.2017.02.014
22. Zeidan E, Shivaji R, Henrich VC, Sandros MG (2016) Nano-SPRi aptasensor for the detection
of progesterone in buffer. Sci Rep 6:26714
23. Lee BH, Nguyen VT, Gu MB (2017) Highly sensitive detection of 25-HydroxyvitaminD(3)
by using a target-induced displacement of aptamer. Biosens Bioelectron 88:174–180. https://
doi.org/10.1016/j.bios.2016.08.011
24. Martin JA, Chávez JL, Chushak Y, Chapleau RR, Hagen J, Kelley-Loughnane N (2014)
Tunable stringency aptamer selection and gold nanoparticle assay for detection of cortisol.
Anal Bioanal Chem 406(19):4637–4647. https://doi.org/10.1007/s00216-014-7883-8
25. Yoshida W, Mochizuki E, Takase M, Hasegawa H, Morita Y, Yamazaki H, Sode K, Ikebukuro
K (2009) Selection of DNA aptamers against insulin and construction of an aptameric enzyme
subunit for insulin sensing. Biosens Bioelectron 24(5):1116–1120. https://doi.org/10.1016/j.
bios.2008.06.016
26. Gerasimov JY, Schaefer CS, Yang W, Grout RL, Lai RY (2013) Development of an electrochemical insulin sensor based on the insulin-linked polymorphic region. Biosens Bioelectron
42:62–68. https://doi.org/10.1016/j.bios.2012.10.046
27. Flood PF, Tyler NJ, Read EK, Rodway MJ, Chedrese PJ (2005) Ovarian and placental production of progesterone and oestradiol during pregnancy in reindeer. Animal reproduction science
85(1–2):147–162. https://doi.org/10.1016/j.anireprosci.2004.03.001
28. Tai SS, Xu B, Welch MJ (2006) Development and evaluation of a candidate reference measurement procedure for the determination of progesterone in human serum using isotope-dilution
liquid chromatography/tandem mass spectrometry. Anal Chem 78(18):6628–6633. https://
doi.org/10.1021/ac060936b
345
13. Akki SU, Werth CJ, Silverman SK (2015) Selective aptamers for detection of estradiol and
ethynylestradiol in natural waters. Environ Sci Technol 49(16):9905–9913. https://doi.org/
10.1021/acs.est.5b02401
14. Vanschoenbeek K, Vanbrabant J, Hosseinkhani B, Vermeeren V, Michiels L (2015) Aptamers
targeting different functional groups of 17β-estradiol. J Steroid Biochem Mol Biol 147:10–16.
https://doi.org/10.1016/j.jsbmb.2014.10.013
15. Svobodová M, Skouridou V, Botero ML, Jauset-Rubio M, Schubert T, Bashammakh AS,
El-Shahawi MS, Alyoubi AO, O’Sullivan CK (2017) The characterization and validation of
17β-estradiol binding aptamers. J Steroid Biochem Mol Biol 167:14–22. https://doi.org/10.
1016/j.jsbmb.2016.09.018
16. Kim JY, Park JH, Kim MI, Lee HH, Kim HL, Jeong KS, Moon SO, Kang PW, Park KW, Lee
YH, Chun BW (2018) Identification of female-specific blood stains using a 17β-estradioltargeted aptamer-based sensor. Int J Legal Med 132(1):91–98. https://doi.org/10.1007/s00
414-017-1718-z
17. Huang H, Shi S, Gao X, Gao R, Zhu Y, Wu X, Zang R, Yao T (2016) A universal labelfree fluorescent aptasensor based on Ru complex and quantum dots for adenosine, dopamine
and 17β-estradiol detection. Biosens Bioelectron 79:198–204. https://doi.org/10.1016/j.bios.
2015.12.024
18. Yao L, Li Y, Cheng K, Pan D, Xu J, Chen W (2019) Determination of 17β-estradiol by
surface-enhanced Raman spectroscopy merged with hybridization chain reaction amplification on Au@Ag core-shell nanoparticles. Mikrochim Acta 186(2):52. https://doi.org/10.1007/
s00604-018-3114-x
19. Ming T, Wang Y, Luo J, Liu J, Sun S, Xing Y, Xiao G, Jin H, Cai X (2019) Folding paperbased aptasensor platform coated with novel nanoassemblies for instant and highly sensitive
detection of 17beta-Estradiol. ACS Sens 4(12):3186–3194. https://doi.org/10.1021/acssen
sors.9b01633
20. Contreras Jiménez G, Eissa S, Ng A, Alhadrami H, Zourob M, Siaj M (2015) Aptamer-based
label-free impedimetric biosensor for detection of progesterone. Anal Chem 87(2):1075–
1082. https://doi.org/10.1021/ac503639s
21. Alhadrami HA, Chinnappan R, Eissa S, Rahamn AA, Zourob M (2017) High affinity truncated
DNA aptamers for the development of fluorescence based progesterone biosensors. Anal
Biochem 525:78–84. https://doi.org/10.1016/j.ab.2017.02.014
22. Zeidan E, Shivaji R, Henrich VC, Sandros MG (2016) Nano-SPRi aptasensor for the detection
of progesterone in buffer. Sci Rep 6:26714
23. Lee BH, Nguyen VT, Gu MB (2017) Highly sensitive detection of 25-HydroxyvitaminD(3)
by using a target-induced displacement of aptamer. Biosens Bioelectron 88:174–180. https://
doi.org/10.1016/j.bios.2016.08.011
24. Martin JA, Chávez JL, Chushak Y, Chapleau RR, Hagen J, Kelley-Loughnane N (2014)
Tunable stringency aptamer selection and gold nanoparticle assay for detection of cortisol.
Anal Bioanal Chem 406(19):4637–4647. https://doi.org/10.1007/s00216-014-7883-8
25. Yoshida W, Mochizuki E, Takase M, Hasegawa H, Morita Y, Yamazaki H, Sode K, Ikebukuro
K (2009) Selection of DNA aptamers against insulin and construction of an aptameric enzyme
subunit for insulin sensing. Biosens Bioelectron 24(5):1116–1120. https://doi.org/10.1016/j.
bios.2008.06.016
26. Gerasimov JY, Schaefer CS, Yang W, Grout RL, Lai RY (2013) Development of an electrochemical insulin sensor based on the insulin-linked polymorphic region. Biosens Bioelectron
42:62–68. https://doi.org/10.1016/j.bios.2012.10.046
27. Flood PF, Tyler NJ, Read EK, Rodway MJ, Chedrese PJ (2005) Ovarian and placental production of progesterone and oestradiol during pregnancy in reindeer. Animal reproduction science
85(1–2):147–162. https://doi.org/10.1016/j.anireprosci.2004.03.001
28. Tai SS, Xu B, Welch MJ (2006) Development and evaluation of a candidate reference measurement procedure for the determination of progesterone in human serum using isotope-dilution
liquid chromatography/tandem mass spectrometry. Anal Chem 78(18):6628–6633. https://
doi.org/10.1021/ac060936b