7 Aptamers for Personalized Therapeutics
203
64. Wang K, Wu D, Chen Z, Zhang X, Yang X, Yang CJ, Lan X (2016) Inhibition of the
superantigenic activities of Staphylococcal enterotoxin A by an aptamer antagonist. Toxicon
119:21–27
65. Lahousse M, Park H-C, Lee S-C, Ha N-R, Jung I-P, Schlesinger SR, Shackelford K, Yoon
M-Y, Kim S-K (2018) Inhibition of anthrax lethal factor by ssDNA aptamers. Arch Biochem
Biophys 646:16–23
66. Chang T-W, Blank M, Janardhanan P, Singh BR, Mello C, Blind M, Cai S (2010) In vitro
selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin. Biochem
Biophys Res Commun 396(4):854–860
67. Chuang Y-M, Belchis DA, Karakousis PC (2013) The polyphosphate kinase gene ppk2 is
required for Mycobacterium tuberculosis inorganic polyphosphate regulation and virulence.
MBio 4(3):e00039-e113
68. Shum KT, Lui ELH, Wong SCK, Yeung P, Sam L, Wang Y, Watt RM, Tanner JA
(2011) Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase
2. Biochemistry 50(15):3261–3271
69. Thongtan T, Wikan N, Wintachai P, Rattanarungsan C, Srisomsap C, Cheepsunthorn P, Smith
DR (2012) Characterization of putative Japanese encephalitis virus receptor molecules on
microglial cells. J Med Virol 84(4):615–623
70. Hovanessian AG (2006) Midkine, a cytokine that inhibits HIV infection by binding to the cell
surface expressed nucleolin. Cell Res 16(2):174–181
71. Balinsky CA, Schmeisser H, Ganesan S, Singh K, Pierson TC, Zoon KC (2013) Nucleolin
interacts with the dengue virus capsid protein and plays a role in formation of infectious virus
particles. J Virol 87(24):13094–13106
72. Skehel JJ, Wiley DC (2000) Receptor binding and membrane fusion in virus entry: the
influenza hemagglutinin. Annu Rev Biochem 69(1):531–569
73. Eckert DM, Kim PS (2001) Mechanisms of viral membrane fusion and its inhibition. Annu
Rev Biochem 70(1):777–810
74. Kwon H-M, Lee KH, Han BW, Han MR, Kim DH, Kim D-E (2014) An RNA aptamer that
specifically binds to the glycosylated hemagglutinin of avian influenza virus and suppresses
viral infection in cells. PLoS ONE 9(5):e97574
75. Choi SK, Lee C, Lee KS, Choe S-Y, Mo IP, Seong RH, Hong S, Jeon SH (2011) DNA aptamers
against the receptor binding region of hemagglutinin prevent avian influenza viral infection.
Mol Cells 32(6):527–533
76. Carf´ ı A, Willis SH, Whitbeck JC, Krummenacher C, Cohen GH, Eisenberg RJ, Wiley DC
(2001) Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol Cell
8(1):169–179
77. Gopinath SC, Hayashi K, Kumar PK (2012) Aptamer that binds to the gD protein of herpes
simplex virus 1 and efficiently inhibits viral entry. J Virol 86(12):6732–6744
78. Yadavalli T, Agelidis A, Jaishankar D, Mangano K, Thakkar N, Penmetcha K, Shukla D (2017)
Targeting herpes simplex virus-1 gD by a DNA aptamer can be an effective new strategy to
curb viral infection. Mol Ther Nucl Acids 9:365–378
79. Yoon S, Rossi JJ (2018) Aptamers: uptake mechanisms and intracellular applications. Adv
Drug Deliv Rev 134:22–35
80. Jung JI, Han SR, Lee S-W (2018) Development of RNA aptamer that inhibits methyltransferase activity of dengue virus. Biotech Lett 40(2):315–324
81. Han SR, Lee S-W (2017) Inhibition of Japanese encephalitis virus (JEV) replication by specific
RNA aptamer against JEV methyltransferase. Biochem Biophys Res Commun 483(1):687–
693
82. Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, Lemm J, Colonno RJ (2000) De novo
initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C
virus. J Virol 74(2):851–863
83. Cheney IW, Naim S, Lai VC, Dempsey S, Bellows D, Walker MP, Shim JH, Horscroft N,
Hong Z, Zhong W (2002) Mutations in NS5B polymerase of hepatitis C virus: impacts on
in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture.
Virology 297(2):298–306
203
64. Wang K, Wu D, Chen Z, Zhang X, Yang X, Yang CJ, Lan X (2016) Inhibition of the
superantigenic activities of Staphylococcal enterotoxin A by an aptamer antagonist. Toxicon
119:21–27
65. Lahousse M, Park H-C, Lee S-C, Ha N-R, Jung I-P, Schlesinger SR, Shackelford K, Yoon
M-Y, Kim S-K (2018) Inhibition of anthrax lethal factor by ssDNA aptamers. Arch Biochem
Biophys 646:16–23
66. Chang T-W, Blank M, Janardhanan P, Singh BR, Mello C, Blind M, Cai S (2010) In vitro
selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin. Biochem
Biophys Res Commun 396(4):854–860
67. Chuang Y-M, Belchis DA, Karakousis PC (2013) The polyphosphate kinase gene ppk2 is
required for Mycobacterium tuberculosis inorganic polyphosphate regulation and virulence.
MBio 4(3):e00039-e113
68. Shum KT, Lui ELH, Wong SCK, Yeung P, Sam L, Wang Y, Watt RM, Tanner JA
(2011) Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase
2. Biochemistry 50(15):3261–3271
69. Thongtan T, Wikan N, Wintachai P, Rattanarungsan C, Srisomsap C, Cheepsunthorn P, Smith
DR (2012) Characterization of putative Japanese encephalitis virus receptor molecules on
microglial cells. J Med Virol 84(4):615–623
70. Hovanessian AG (2006) Midkine, a cytokine that inhibits HIV infection by binding to the cell
surface expressed nucleolin. Cell Res 16(2):174–181
71. Balinsky CA, Schmeisser H, Ganesan S, Singh K, Pierson TC, Zoon KC (2013) Nucleolin
interacts with the dengue virus capsid protein and plays a role in formation of infectious virus
particles. J Virol 87(24):13094–13106
72. Skehel JJ, Wiley DC (2000) Receptor binding and membrane fusion in virus entry: the
influenza hemagglutinin. Annu Rev Biochem 69(1):531–569
73. Eckert DM, Kim PS (2001) Mechanisms of viral membrane fusion and its inhibition. Annu
Rev Biochem 70(1):777–810
74. Kwon H-M, Lee KH, Han BW, Han MR, Kim DH, Kim D-E (2014) An RNA aptamer that
specifically binds to the glycosylated hemagglutinin of avian influenza virus and suppresses
viral infection in cells. PLoS ONE 9(5):e97574
75. Choi SK, Lee C, Lee KS, Choe S-Y, Mo IP, Seong RH, Hong S, Jeon SH (2011) DNA aptamers
against the receptor binding region of hemagglutinin prevent avian influenza viral infection.
Mol Cells 32(6):527–533
76. Carf´ ı A, Willis SH, Whitbeck JC, Krummenacher C, Cohen GH, Eisenberg RJ, Wiley DC
(2001) Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol Cell
8(1):169–179
77. Gopinath SC, Hayashi K, Kumar PK (2012) Aptamer that binds to the gD protein of herpes
simplex virus 1 and efficiently inhibits viral entry. J Virol 86(12):6732–6744
78. Yadavalli T, Agelidis A, Jaishankar D, Mangano K, Thakkar N, Penmetcha K, Shukla D (2017)
Targeting herpes simplex virus-1 gD by a DNA aptamer can be an effective new strategy to
curb viral infection. Mol Ther Nucl Acids 9:365–378
79. Yoon S, Rossi JJ (2018) Aptamers: uptake mechanisms and intracellular applications. Adv
Drug Deliv Rev 134:22–35
80. Jung JI, Han SR, Lee S-W (2018) Development of RNA aptamer that inhibits methyltransferase activity of dengue virus. Biotech Lett 40(2):315–324
81. Han SR, Lee S-W (2017) Inhibition of Japanese encephalitis virus (JEV) replication by specific
RNA aptamer against JEV methyltransferase. Biochem Biophys Res Commun 483(1):687–
693
82. Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, Lemm J, Colonno RJ (2000) De novo
initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C
virus. J Virol 74(2):851–863
83. Cheney IW, Naim S, Lai VC, Dempsey S, Bellows D, Walker MP, Shim JH, Horscroft N,
Hong Z, Zhong W (2002) Mutations in NS5B polymerase of hepatitis C virus: impacts on
in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture.
Virology 297(2):298–306