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E, Surendran P, Oliver-Williams C, Kamat MA, Prins BP, Wilcox SK, Zimmerman ES, Chi A,
Bansal N, Spain SL, Wood AM, Morrell NW, Bradley JR, Janjic N, Roberts DJ, Ouwehand WH,
Todd JA, Soranzo N, Suhre K, Paul DS, Fox CS, Plenge RM, Danesh J, Runz H, Butterworth
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13. Joshi A, Mayr M (2018) In aptamers they trust: caveats of the somascan biomarker discovery
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An aptasensor for the detection of mycobacterium tuberculosis secreted immunogenic protein
Mpt64 in clinical samples towards tuberculosis detection. Sci Rep 9:11
19. Sinha A, Gopinathan P, Chung YD, Shiesh SC, Lee GB (2019) Simultaneous detection of
multiple nt-probnp clinical samples utilizing an aptamer-based sandwich assay on an integrated
microfluidic system. Lab Chip 19(9):1676–1685
20. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2017) May 4,
Identifier: NCT03140709. Non-Invasive, Highly Specific Detection of Oxytocin in Biological
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21. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2019) Apr
16, Identifier: NCT03915002. Integrated Approaches for Identifying Molecular Targets in Liver
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22. Schwartz JJ, Thompson JD, Bajaj VS (2018) Aptamer-based sensors, implantable devices and
detection system. United States Patent 10028659
23. Schwartz JJ, Bajaj VS, Thompson JD (2018) Aptamer-based in vivo diagnostic system. United
States Patent 9874554
24. Schwartz JJ, Bajaj VS, Thompson JD (2018) Aptamer-based analyte detection system and
sensor. United States Patent 10034625
25. Schwartz JJ, Thompson JD, Bajaj VS (2016) Aptamer-based sensors, implantable devices and
detection system. United States Patent 20160278638
26. Hall DR, Allen D, Rosenbrock C, Hendricks D, Nguyen A, Butala SJM, Niederhauser T,
Pearman T, Fox J (2018) Medical toilet with aptamer sensors to analyze urine. United States
Patent 20180321218
27. Yu Q, Zhao Q, Wang S, Zhao S, Zhang S, Yin YG, Dong YY (2020) Development of a lateral
flow aptamer assay strip for facile identification of theranostic exosomes isolated from human
lung carcinoma cells. Anal Biochem 594:7
28. Kim J, Park W, Kim D, Lee ES, Lee DH, Jeong S, Park JM, Na K (2019) Tumor-specific
aptamer-conjugated polymeric photosensitizer for effective endo-laparoscopic photodynamic
therapy. Adv Funct Mater 29(23):11
29. Bloembergen S, Mclennan IJ, Jones N, Wagner R, Ganesh S, Aareet K, Elsayed AR, Liu J
(2012) Aptamer bioconjugate drug delivery device. United States Patent 20120141551
B. Liu et al.
12. Sun BB, Maranville JC, Peters JE, Stacey D, Staley JR, Blackshaw J, Burgess S, Jiang T, Paige
E, Surendran P, Oliver-Williams C, Kamat MA, Prins BP, Wilcox SK, Zimmerman ES, Chi A,
Bansal N, Spain SL, Wood AM, Morrell NW, Bradley JR, Janjic N, Roberts DJ, Ouwehand WH,
Todd JA, Soranzo N, Suhre K, Paul DS, Fox CS, Plenge RM, Danesh J, Runz H, Butterworth
AS (2018) Genomic atlas of the human plasma proteome. Nature 558(7708):73
13. Joshi A, Mayr M (2018) In aptamers they trust: caveats of the somascan biomarker discovery
platform from somalogic. Circulation 138(22):2482–2485
14. Marketwired (2015) Somalogic announces agreement to place somascan(Tm) proteomics assay
at manitoba centre for proteomics and systems biology. yahoo. https://finance.yahoo.com/news/
somalogic-announces-agreement-place-somascan-160000527.html. Accessed 25 April 2020
15. SomaLogic (2020) Patents−Somalogic. SomaLogic. https://somalogic.com/technology/pat
ents/. Accessed 25 April 2020
16. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2018) Aug
24, Identifier: NCT03646708. Response Assessment in SB CD; [cited 2020 Apr 25, 4 pages].
https://clinicaltrials.gov/ct2/show/NCT03646708
17. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2016) Jun
10, Identifier: NCT02957370. Molecular Biosensors for Detection of Bladder Cancer; [cited
2020 Apr 25, 4 pages]. https://clinicaltrials.gov/ct2/show/record/NCT02957370
18. Sypabekova M, Dukenbayev K, Tsepke A, Akisheva A, Oralbayev N, Kanayeva D (2019)
An aptasensor for the detection of mycobacterium tuberculosis secreted immunogenic protein
Mpt64 in clinical samples towards tuberculosis detection. Sci Rep 9:11
19. Sinha A, Gopinathan P, Chung YD, Shiesh SC, Lee GB (2019) Simultaneous detection of
multiple nt-probnp clinical samples utilizing an aptamer-based sandwich assay on an integrated
microfluidic system. Lab Chip 19(9):1676–1685
20. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2017) May 4,
Identifier: NCT03140709. Non-Invasive, Highly Specific Detection of Oxytocin in Biological
Fluids; [cited 2020 Apr 25, 4 pages]. https://clinicaltrials.gov/ct2/show/record/NCT03140709
21. ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US) (2019) Apr
16, Identifier: NCT03915002. Integrated Approaches for Identifying Molecular Targets in Liver
Disease (InLi); [cited 2020 Apr 25, 4 pages]. https://clinicaltrials.gov/ct2/show/NCT03915002
22. Schwartz JJ, Thompson JD, Bajaj VS (2018) Aptamer-based sensors, implantable devices and
detection system. United States Patent 10028659
23. Schwartz JJ, Bajaj VS, Thompson JD (2018) Aptamer-based in vivo diagnostic system. United
States Patent 9874554
24. Schwartz JJ, Bajaj VS, Thompson JD (2018) Aptamer-based analyte detection system and
sensor. United States Patent 10034625
25. Schwartz JJ, Thompson JD, Bajaj VS (2016) Aptamer-based sensors, implantable devices and
detection system. United States Patent 20160278638
26. Hall DR, Allen D, Rosenbrock C, Hendricks D, Nguyen A, Butala SJM, Niederhauser T,
Pearman T, Fox J (2018) Medical toilet with aptamer sensors to analyze urine. United States
Patent 20180321218
27. Yu Q, Zhao Q, Wang S, Zhao S, Zhang S, Yin YG, Dong YY (2020) Development of a lateral
flow aptamer assay strip for facile identification of theranostic exosomes isolated from human
lung carcinoma cells. Anal Biochem 594:7
28. Kim J, Park W, Kim D, Lee ES, Lee DH, Jeong S, Park JM, Na K (2019) Tumor-specific
aptamer-conjugated polymeric photosensitizer for effective endo-laparoscopic photodynamic
therapy. Adv Funct Mater 29(23):11
29. Bloembergen S, Mclennan IJ, Jones N, Wagner R, Ganesh S, Aareet K, Elsayed AR, Liu J
(2012) Aptamer bioconjugate drug delivery device. United States Patent 20120141551