120
B. Liu et al.
(a)
(b)
Fig. 5.2 An experimental set-up a real, and b schematic comprising a PC and electrodes that were
connected to the portable potentiostat. Reprinted by permission from Springer Nature: Ref. [18],
copyright 2019
Heart failure (HF) threatens the health of millions of people. Monitoring the
circulatory levels of a relatively new biomarker, N-terminal prohormone of B-type
natriuretic peptide (NT-proBNP), is a meaningful way for the early risk evaluation
of HF. Sinha et al. [19] developed an ingeniously designed, pneumatically-driven,
automatic integrated microfluidic platform equipped with micropumps, micromixers,
and microvalves for the simultaneous detection of NT-proBNP (Fig. 5.3). Six clinical
samples could be analyzed within as short as 25 min through the aptamer-based
sandwich assay. This method may serve as a promising tool for early diagnosis of
HF, and the integrated microfluidic chip can be extended for the detection of other
B. Liu et al.
(a)
(b)
Fig. 5.2 An experimental set-up a real, and b schematic comprising a PC and electrodes that were
connected to the portable potentiostat. Reprinted by permission from Springer Nature: Ref. [18],
copyright 2019
Heart failure (HF) threatens the health of millions of people. Monitoring the
circulatory levels of a relatively new biomarker, N-terminal prohormone of B-type
natriuretic peptide (NT-proBNP), is a meaningful way for the early risk evaluation
of HF. Sinha et al. [19] developed an ingeniously designed, pneumatically-driven,
automatic integrated microfluidic platform equipped with micropumps, micromixers,
and microvalves for the simultaneous detection of NT-proBNP (Fig. 5.3). Six clinical
samples could be analyzed within as short as 25 min through the aptamer-based
sandwich assay. This method may serve as a promising tool for early diagnosis of
HF, and the integrated microfluidic chip can be extended for the detection of other