112
Z. Liu and Y. Liu
107. Norouzi M, Nazari B, Miller DW (2016) Injectable hydrogel-based drug delivery systems for
local cancer therapy. Drug Discovery Today 21(11):1835–1849
108. Xue H, Ding F, Zhang J, Guo Y, Gao X, Feng J, Zhu X, Zhang C (2019) DNA tetrahedron-based
nanogels for siRNA delivery and gene silencing. Chem Commun (Camb) 55(29):4222–4225
109. Yang F, Cheng Y, Zhang Y, Wei W, Dong H, Lu H, Zhang X (2020) Bioinspired framework
nucleic acid capture sensitively and rapidly resolving microRNAs biomarkers in living cells.
Anal Chem 92(6):4411–4418
110. Liu Q, Wang D, Xu Z, Huang C, Zhang C, He B, Mao C, Wang G, Qian H (2019)
Targeted delivery of Rab26 siRNA with precisely tailored DNA prism for lung cancer therapy.
Chembiochem Eur J Chem Biol 20(9):1139–1144
111. Hu Y, Wang Y, Yan J, Wen N, Xiong H, Cai S, He Q, Peng D, Liu Z, Liu Y (2020)
Dynamic DNA assemblies in biomedical applications. Adv Sci. https://doi.org/10.1002/advs.
202000557
112. Wu C, Han D, Chen T, Peng L, Zhu G, You M, Qiu L, Sefah K, Zhang X, Tan W (2013)
Building a multifunctional aptamer-based DNA nanoassembly for targeted cancer therapy. J
Am Chem Soc 135(49):18644–18650
113. Zhang H, Ma Y, Xie Y, An Y, Huang Y, Zhu Z, Yang CJ (2015) A controllable aptamer-based
self-assembled DNA dendrimer for high affinity targeting, bioimaging and drug delivery.
Scient Rep 5:10099
114. Li N, Wang XY, Xiang MH, Liu JW, Yu RQ, Jiang JH (2019) Programmable self-assembly of
protein-scaffolded DNA nanohydrogels for tumor-targeted imaging and therapy. Anal Chem
91(4):2610–2614
115. Sun S, Cheraga N, Jiang HN, Xiao QR, Gao PC, Wang Y, Wei YY, Wang XW, Jiang Y
(2020) Bioinspired DNA nanocockleburs for targeted delivery of doxorubicin. Colloids Surf
B Biointer 186:110733
116. Wei H, Zhao Z, Wang Y, Zou J, Lin Q, Duan Y (2019) One-step self-assembly of multifunctional DNA nanohydrogels: an enhanced and harmless strategy for guiding combined
antitumor therapy. ACS Appl Mater Inter 11(50):46479–46489
117. Wang J, Wang H, Wang H, He S, Li R, Deng Z, Liu X, Wang F (2019) Nonviolent self-catabolic
DNAzyme nanosponges for smart anticancer drug delivery. ACS Nano 13(5):5852–5863
118. Zhang K, Liu J, Song Q, Yang X, Wang D, Liu W, Shi J, Zhang Z (2019) DNA nanosponge
for adsorption and clearance of intracellular miR-21 and enhanced antitumor chemotherapy.
ACS Appl Mater Inter 11(50):46604–46613
119. Ding L, Li J, Wu C, Yan F, Li X, Zhang S (2020) A self-assembled RNA-triple helix hydrogel
drug delivery system targeting triple-negative breast cancer. J Mater Chem B 8(16):3527–3533
120. Jie G, Gao X, Ge J, Li C (2019) Multifunctional DNA nanocage with CdTe quantum dots
for fluorescence detection of human 8-oxoG DNA glycosylase 1 and doxorubicin delivery to
cancer cells. Mikrochim Acta 186(2):85
121. Ma W, Zhang Y, Zhang Y, Shao X, Xie X, Mao C, Cui W, Li Q, Shi J, Li J, Fan C, Lin Y
(2019) An intelligent DNA nanorobot with in vitro enhanced protein lysosomal degradation
of HER2. Nano Lett 19(7):4505–4517
122. Tung J, Tew LS, Hsu YM, Khung YL (2017) A novel 4-arm DNA/RNA nanoconstruct triggering rapid apoptosis of triple negative breast cancer cells within 24 hours. Scient Rep
7(1):793
123. Yao F, An Y, Li X, Li Z, Duan J, Yang XD (2020) Targeted therapy of colon cancer by aptamerguided holliday junctions loaded with doxorubicin. Int J Nanomedicine 15:2119–2129
124. Yin H, Xiong G, Guo S, Xu C, Xu R, Guo P, Shu D (2019) Delivery of anti-miRNA for triplenegative breast cancer therapy using RNA nanoparticles targeting stem cell marker CD133.
Mol Ther 27(7):1252–1261
125. Lin HC, Li WT, Madanayake TW, Tao C, Niu Q, Yan SQ, Gao BA, Ping Z (2020) Aptamerguided upconversion nanoplatform for targeted drug delivery and near-infrared light-triggered
photodynamic therapy. J Biomater Appl 34(6):875–888
126. Zhou C, Chen T, Wu C, Zhu G, Qiu L, Cui C, Hou W, Tan W (2015) Aptamer CaCO 3
nanostructures: a facile, pH-responsive, specific platform for targeted anticancer theranostics.
Chem Asian J 10(1):166–171
Z. Liu and Y. Liu
107. Norouzi M, Nazari B, Miller DW (2016) Injectable hydrogel-based drug delivery systems for
local cancer therapy. Drug Discovery Today 21(11):1835–1849
108. Xue H, Ding F, Zhang J, Guo Y, Gao X, Feng J, Zhu X, Zhang C (2019) DNA tetrahedron-based
nanogels for siRNA delivery and gene silencing. Chem Commun (Camb) 55(29):4222–4225
109. Yang F, Cheng Y, Zhang Y, Wei W, Dong H, Lu H, Zhang X (2020) Bioinspired framework
nucleic acid capture sensitively and rapidly resolving microRNAs biomarkers in living cells.
Anal Chem 92(6):4411–4418
110. Liu Q, Wang D, Xu Z, Huang C, Zhang C, He B, Mao C, Wang G, Qian H (2019)
Targeted delivery of Rab26 siRNA with precisely tailored DNA prism for lung cancer therapy.
Chembiochem Eur J Chem Biol 20(9):1139–1144
111. Hu Y, Wang Y, Yan J, Wen N, Xiong H, Cai S, He Q, Peng D, Liu Z, Liu Y (2020)
Dynamic DNA assemblies in biomedical applications. Adv Sci. https://doi.org/10.1002/advs.
202000557
112. Wu C, Han D, Chen T, Peng L, Zhu G, You M, Qiu L, Sefah K, Zhang X, Tan W (2013)
Building a multifunctional aptamer-based DNA nanoassembly for targeted cancer therapy. J
Am Chem Soc 135(49):18644–18650
113. Zhang H, Ma Y, Xie Y, An Y, Huang Y, Zhu Z, Yang CJ (2015) A controllable aptamer-based
self-assembled DNA dendrimer for high affinity targeting, bioimaging and drug delivery.
Scient Rep 5:10099
114. Li N, Wang XY, Xiang MH, Liu JW, Yu RQ, Jiang JH (2019) Programmable self-assembly of
protein-scaffolded DNA nanohydrogels for tumor-targeted imaging and therapy. Anal Chem
91(4):2610–2614
115. Sun S, Cheraga N, Jiang HN, Xiao QR, Gao PC, Wang Y, Wei YY, Wang XW, Jiang Y
(2020) Bioinspired DNA nanocockleburs for targeted delivery of doxorubicin. Colloids Surf
B Biointer 186:110733
116. Wei H, Zhao Z, Wang Y, Zou J, Lin Q, Duan Y (2019) One-step self-assembly of multifunctional DNA nanohydrogels: an enhanced and harmless strategy for guiding combined
antitumor therapy. ACS Appl Mater Inter 11(50):46479–46489
117. Wang J, Wang H, Wang H, He S, Li R, Deng Z, Liu X, Wang F (2019) Nonviolent self-catabolic
DNAzyme nanosponges for smart anticancer drug delivery. ACS Nano 13(5):5852–5863
118. Zhang K, Liu J, Song Q, Yang X, Wang D, Liu W, Shi J, Zhang Z (2019) DNA nanosponge
for adsorption and clearance of intracellular miR-21 and enhanced antitumor chemotherapy.
ACS Appl Mater Inter 11(50):46604–46613
119. Ding L, Li J, Wu C, Yan F, Li X, Zhang S (2020) A self-assembled RNA-triple helix hydrogel
drug delivery system targeting triple-negative breast cancer. J Mater Chem B 8(16):3527–3533
120. Jie G, Gao X, Ge J, Li C (2019) Multifunctional DNA nanocage with CdTe quantum dots
for fluorescence detection of human 8-oxoG DNA glycosylase 1 and doxorubicin delivery to
cancer cells. Mikrochim Acta 186(2):85
121. Ma W, Zhang Y, Zhang Y, Shao X, Xie X, Mao C, Cui W, Li Q, Shi J, Li J, Fan C, Lin Y
(2019) An intelligent DNA nanorobot with in vitro enhanced protein lysosomal degradation
of HER2. Nano Lett 19(7):4505–4517
122. Tung J, Tew LS, Hsu YM, Khung YL (2017) A novel 4-arm DNA/RNA nanoconstruct triggering rapid apoptosis of triple negative breast cancer cells within 24 hours. Scient Rep
7(1):793
123. Yao F, An Y, Li X, Li Z, Duan J, Yang XD (2020) Targeted therapy of colon cancer by aptamerguided holliday junctions loaded with doxorubicin. Int J Nanomedicine 15:2119–2129
124. Yin H, Xiong G, Guo S, Xu C, Xu R, Guo P, Shu D (2019) Delivery of anti-miRNA for triplenegative breast cancer therapy using RNA nanoparticles targeting stem cell marker CD133.
Mol Ther 27(7):1252–1261
125. Lin HC, Li WT, Madanayake TW, Tao C, Niu Q, Yan SQ, Gao BA, Ping Z (2020) Aptamerguided upconversion nanoplatform for targeted drug delivery and near-infrared light-triggered
photodynamic therapy. J Biomater Appl 34(6):875–888
126. Zhou C, Chen T, Wu C, Zhu G, Qiu L, Cui C, Hou W, Tan W (2015) Aptamer CaCO 3
nanostructures: a facile, pH-responsive, specific platform for targeted anticancer theranostics.
Chem Asian J 10(1):166–171