4 Aptamer-Based Drug Delivery Systems
109
52. Zhao C, Liu Z (2014) Application of gold nanoparticles in cancer therapy. Zhongguo Yi Xue
Ke Xue Yuan Xue Bao 36(3):324–329
53. Ruttala HB, Ramasamy T, Poudel BK, Ruttala RRT, Jin SG, Choi HG, Ku SK, Yong CS, Kim
JO (2020) Multi-responsive albumin-lonidamine conjugated hybridized gold nanoparticle
as a combined photothermal-chemotherapy for synergistic tumor ablation. Acta Biomater
101:531–543
54. Niu W, Chen X, Tan W, Veige AS (2016) N-heterocyclic carbene-gold(I) complexes conjugated to a leukemia-specific DNA aptamer for targeted drug delivery. Angewandte Chemie
Int Edit 55(31):8889–8893
55. Wang X-W, Gao W, Fan H, Ding D, Lai X-F, Zou Y-X, Chen L, Chen Z, Tan W (2016)
Simultaneous tracking of drug molecules and carriers using aptamer-functionalized fluorescent superstable gold nanorod-carbon nanocapsules during thermo-chemotherapy. Nanoscale
8(15):7942–7948
56. Yang Y, Zhao W, Tan W, Lai Z, Fang D, Jiang L, Zuo C, Yang N, Lai Y (2019) An efficient celltargeting drug delivery system based on aptamer-modified mesoporous silica nanoparticles.
Nano Res Lett 14(1):390
57. Vandghanooni S, Barar J, Eskandani M, Omidi Y (2020) Aptamer-conjugated mesoporous
silica nanoparticles for simultaneous imaging and therapy of cancer. TrAC Trends Anal Chem
123:115759
58. Xie X, Li F, Zhang H, Lu Y, Lian S, Lin H, Gao Y, Jia L (2016) EpCAM aptamer-functionalized
mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery. Eur J
Pharmaceut Sci 83:28–35
59. Wang Y, Wang L, Guo L, Yan M, Feng L, Dong S, Hao J (2019) Photo-responsive magnetic
mesoporous silica nanocomposites for magnetic targeted cancer therapy. New J Chem
43(12):4908–4918
60. Sun P, Leidner A, Weigel S, Weidler PG, Heissler S, Scharnweber T, Niemeyer CM (2019)
Biopebble containers: DNA-directed surface assembly of mesoporous silica nanoparticles for
cell studies. Small 15(20):e1900083
61. Zahiri M, Babaei M, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M (2020) Hybrid
nanoreservoirs based on dextran-capped dendritic mesoporous silica nanoparticles for CD133targeted drug delivery. J Cell Physiol 235(2):1036–1050
62. Baneshi M, Dadfarnia S, Shabani AMH, Sabbagh SK, Haghgoo S, Bardania H (2019) A novel
theranostic system of AS1411 aptamer-functionalized albumin nanoparticles loaded on iron
oxide and gold nanoparticles for doxorubicin delivery. Int J Pharmaceut 564:145–152
63. Kolovskaya OS, Zamay TN, Zamay GS, Babkin VA, Medvedeva EN, Neverova NA,
Kirichenko AK, Zamay SS, Lapin IN, Morozov EV, Sokolov AE, Narodov AA, Fedorov
DG, Tomilin FN, Zabluda VN, Alekhina Y, Lukyanenko KA, Glazyrin YE, Svetlichnyi VA,
Berezovski MV, Kichkailo AS (2020) Aptamer-conjugated superparamagnetic ferroarabinogalactan nanoparticles for targeted magnetodynamic therapy of cancer. Cancers 12(1):17
64. Wang Y, Yan J, Wen N, Xiong H, Cai S, He Q, Hu Y, Peng D, Liu Z, Liu Y (2020) Metal-organic
frameworks for stimuli-responsive drug delivery. Biomaterials 230:119619
65. Chen WH, Yu X, Cecconello A, Sohn YS, Nechushtai R, Willner I (2017) Stimuli-responsive
nucleic acid-functionalized metal-organic framework nanoparticles using pH- and metal-iondependent DNAzymes as locks. Chem Sci 8(8):5769–5780
66. Chen WH, Karmi O, Willner B, Nechushtai R, Willner I (2019) Thrombin aptamer-modified
metal-organic framework nanoparticles: functional nanostructures for sensing thrombin and
the triggered controlled release of anti-blood clotting drugs. Sens (Basel) 19(23):5260
67. Liu Z, Chen S, Liu B, Wu J, Zhou Y, He L, Ding J, Liu J (2014) Intracellular detection of
ATP using an aptamer beacon covalently linked to graphene oxide resisting nonspecific probe
displacement. Anal Chem 86(24):12229–12235
68. Mo R, Jiang T, Sun W, Gu Z (2015) ATP-responsive DNA-graphene hybrid nanoaggregates
for anticancer drug delivery. Biomaterials 50:67–74
69. Du P, Yan J, Long S, Xiong H, Wen N, Cai S, Wang Y, Peng D, Liu Z, Liu Y (2020) Tumor
microenvironment and NIR laser dual-responsive release of berberine 9-O-pyrazole alkyl
109
52. Zhao C, Liu Z (2014) Application of gold nanoparticles in cancer therapy. Zhongguo Yi Xue
Ke Xue Yuan Xue Bao 36(3):324–329
53. Ruttala HB, Ramasamy T, Poudel BK, Ruttala RRT, Jin SG, Choi HG, Ku SK, Yong CS, Kim
JO (2020) Multi-responsive albumin-lonidamine conjugated hybridized gold nanoparticle
as a combined photothermal-chemotherapy for synergistic tumor ablation. Acta Biomater
101:531–543
54. Niu W, Chen X, Tan W, Veige AS (2016) N-heterocyclic carbene-gold(I) complexes conjugated to a leukemia-specific DNA aptamer for targeted drug delivery. Angewandte Chemie
Int Edit 55(31):8889–8893
55. Wang X-W, Gao W, Fan H, Ding D, Lai X-F, Zou Y-X, Chen L, Chen Z, Tan W (2016)
Simultaneous tracking of drug molecules and carriers using aptamer-functionalized fluorescent superstable gold nanorod-carbon nanocapsules during thermo-chemotherapy. Nanoscale
8(15):7942–7948
56. Yang Y, Zhao W, Tan W, Lai Z, Fang D, Jiang L, Zuo C, Yang N, Lai Y (2019) An efficient celltargeting drug delivery system based on aptamer-modified mesoporous silica nanoparticles.
Nano Res Lett 14(1):390
57. Vandghanooni S, Barar J, Eskandani M, Omidi Y (2020) Aptamer-conjugated mesoporous
silica nanoparticles for simultaneous imaging and therapy of cancer. TrAC Trends Anal Chem
123:115759
58. Xie X, Li F, Zhang H, Lu Y, Lian S, Lin H, Gao Y, Jia L (2016) EpCAM aptamer-functionalized
mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery. Eur J
Pharmaceut Sci 83:28–35
59. Wang Y, Wang L, Guo L, Yan M, Feng L, Dong S, Hao J (2019) Photo-responsive magnetic
mesoporous silica nanocomposites for magnetic targeted cancer therapy. New J Chem
43(12):4908–4918
60. Sun P, Leidner A, Weigel S, Weidler PG, Heissler S, Scharnweber T, Niemeyer CM (2019)
Biopebble containers: DNA-directed surface assembly of mesoporous silica nanoparticles for
cell studies. Small 15(20):e1900083
61. Zahiri M, Babaei M, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M (2020) Hybrid
nanoreservoirs based on dextran-capped dendritic mesoporous silica nanoparticles for CD133targeted drug delivery. J Cell Physiol 235(2):1036–1050
62. Baneshi M, Dadfarnia S, Shabani AMH, Sabbagh SK, Haghgoo S, Bardania H (2019) A novel
theranostic system of AS1411 aptamer-functionalized albumin nanoparticles loaded on iron
oxide and gold nanoparticles for doxorubicin delivery. Int J Pharmaceut 564:145–152
63. Kolovskaya OS, Zamay TN, Zamay GS, Babkin VA, Medvedeva EN, Neverova NA,
Kirichenko AK, Zamay SS, Lapin IN, Morozov EV, Sokolov AE, Narodov AA, Fedorov
DG, Tomilin FN, Zabluda VN, Alekhina Y, Lukyanenko KA, Glazyrin YE, Svetlichnyi VA,
Berezovski MV, Kichkailo AS (2020) Aptamer-conjugated superparamagnetic ferroarabinogalactan nanoparticles for targeted magnetodynamic therapy of cancer. Cancers 12(1):17
64. Wang Y, Yan J, Wen N, Xiong H, Cai S, He Q, Hu Y, Peng D, Liu Z, Liu Y (2020) Metal-organic
frameworks for stimuli-responsive drug delivery. Biomaterials 230:119619
65. Chen WH, Yu X, Cecconello A, Sohn YS, Nechushtai R, Willner I (2017) Stimuli-responsive
nucleic acid-functionalized metal-organic framework nanoparticles using pH- and metal-iondependent DNAzymes as locks. Chem Sci 8(8):5769–5780
66. Chen WH, Karmi O, Willner B, Nechushtai R, Willner I (2019) Thrombin aptamer-modified
metal-organic framework nanoparticles: functional nanostructures for sensing thrombin and
the triggered controlled release of anti-blood clotting drugs. Sens (Basel) 19(23):5260
67. Liu Z, Chen S, Liu B, Wu J, Zhou Y, He L, Ding J, Liu J (2014) Intracellular detection of
ATP using an aptamer beacon covalently linked to graphene oxide resisting nonspecific probe
displacement. Anal Chem 86(24):12229–12235
68. Mo R, Jiang T, Sun W, Gu Z (2015) ATP-responsive DNA-graphene hybrid nanoaggregates
for anticancer drug delivery. Biomaterials 50:67–74
69. Du P, Yan J, Long S, Xiong H, Wen N, Cai S, Wang Y, Peng D, Liu Z, Liu Y (2020) Tumor
microenvironment and NIR laser dual-responsive release of berberine 9-O-pyrazole alkyl