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131. Yu Q, Shi J, Mudiyanselage A, Wu R, Zhao B,
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RNA-based sensors for intracellular imaging
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(5):707–710.
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c8cc08796b
132. DasGupta S, Shelke SA, Li NS, Piccirilli JA
(2015) Spinach RNA aptamer detects lead
(II) with high selectivity. Chem Commun
(Camb) 51(43):9034–9037. https://doi.
org/10.1039/c5cc01526j
133. Savage JC, Shinde P, Bachinger HP, Davare
MA, Shinde U (2019) A ribose modification
of Spinach aptamer accelerates lead(ii) cation
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55(42):5882–5885.
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1039/c9cc01697j
134. Verma I, Devi M, Sharma D, Nandi R, Pal SK
(2019) Liquid crystal based detection of Pb
(II) ions using Spinach RNA as recognition
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35(24):7816–7823.
https://doi.org/10.1021/acs.langmuir.
8b04018
135. Panchapakesan SSS, Ferguson ML, Hayden
EJ, Chen X, Hoskins AA, Unrau PJ (2017)
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(10):1592–1599. https://doi.org/10.1261/
rna.062166.117
102
Michael Ryckelynck
Ad O, Yeo J, Hammond MC (2016) Hybrid
promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3
0 ,3
0 -cGAMP). Proc
Natl Acad Sci U S A 113(7):1790–1795.
https://doi.org/10.1073/pnas.
1515287113
124. Inuzuka S, Matsumura S, Ikawa Y (2016)
Optimization of RNA-based c-di-GMP fluorescent sensors through tuning their structural modules. J Biosci Bioeng 122
(2):183–187. https://doi.org/10.1016/j.
jbiosc.2016.01.011
125. Wang C, Sinn M, Stifel J, Heiler AC,
Sommershof A, Hartig JS (2017) Synthesis
of all possible canonical (3
0 -5
0 -linked) cyclic
dinucleotides and evaluation of riboswitch
interactions and immune-stimulatory effects.
J Am Chem Soc 139(45):16154–16160.
https://doi.org/10.1021/jacs.7b06141
126. Autour A, Bouhedda F, Cubi R, Ryckelynck
M (2019) Optimization of fluorogenic
RNA-based biosensors using droplet-based
microfluidic ultrahigh-throughput screening.
Methods 161:46–53. https://doi.org/10.
1016/j.ymeth.2019.03.015
127. Hallberg ZF, Su Y, Kitto RZ, Hammond MC
(2017) Engineering and In Vivo Applications
of Riboswitches. Annu Rev Biochem
86:515–539.
https://doi.org/10.1146/
annurev-biochem-060815-014628
128. Karunanayake Mudiyanselage A, Wu R, LeonDuque MA, Ren K, You M (2019) “Secondgeneration” fluorogenic RNA-based sensors.
Methods 161:24–34. https://doi.org/10.
1016/j.ymeth.2019.01.008
129. Sun Z, Nguyen T, McAuliffe K, You M
(2019) Intracellular imaging with genetically
encoded RNA-based molecular sensors.
Nanomaterials (Basel) 9(2). https://doi.
org/10.3390/nano9020233
130. Abatemarco J, Sarhan MF, Wagner JM, Lin
JL, Liu L, Hassouneh W, Yuan SF, Alper HS,
Abate AR (2017) RNA-aptamers-in-droplets
(RAPID) high-throughput screening for
secretory phenotypes. Nat Commun 8
(1):332. https://doi.org/10.1038/s41467017-00425-7
131. Yu Q, Shi J, Mudiyanselage A, Wu R, Zhao B,
Zhou M, You M (2019) Genetically encoded
RNA-based sensors for intracellular imaging
of silver ions. Chem Commun (Camb) 55
(5):707–710.
https://doi.org/10.1039/
c8cc08796b
132. DasGupta S, Shelke SA, Li NS, Piccirilli JA
(2015) Spinach RNA aptamer detects lead
(II) with high selectivity. Chem Commun
(Camb) 51(43):9034–9037. https://doi.
org/10.1039/c5cc01526j
133. Savage JC, Shinde P, Bachinger HP, Davare
MA, Shinde U (2019) A ribose modification
of Spinach aptamer accelerates lead(ii) cation
association in vitro. Chem Commun (Camb)
55(42):5882–5885.
https://doi.org/10.
1039/c9cc01697j
134. Verma I, Devi M, Sharma D, Nandi R, Pal SK
(2019) Liquid crystal based detection of Pb
(II) ions using Spinach RNA as recognition
probe.
Langmuir
35(24):7816–7823.
https://doi.org/10.1021/acs.langmuir.
8b04018
135. Panchapakesan SSS, Ferguson ML, Hayden
EJ, Chen X, Hoskins AA, Unrau PJ (2017)
Ribonucleoprotein purification and characterization using RNA Mango. RNA 23
(10):1592–1599. https://doi.org/10.1261/
rna.062166.117
102
Michael Ryckelynck